Non-destructive imaging of fragments of historical beeswax seals using high-contrast X-ray micro-radiography and micro-tomography with large area photon-counting detector array

Micron ◽  
2016 ◽  
Vol 91 ◽  
pp. 22-28 ◽  
Author(s):  
Jakub Karch ◽  
Benjamin Bartl ◽  
Jan Dudak ◽  
Jan Zemlicka ◽  
Frantisek Krejci
Keyword(s):  
Photon Counting ◽  
Detector Array ◽  
High Contrast ◽  
Large Area ◽  
X Ray ◽  
Photon Counting Detector ◽  
Micro Tomography ◽  
Non Destructive

scholarly journals High resolution X-ray micro-CT imaging of fibrin scaffold using large area single photon counting detector

2018 ◽  
Vol 13 (12) ◽  
pp. C12006-C12006 ◽  
Author(s):  
D. Vavřík ◽  
D. Kytýř ◽  
S. Mühleder ◽  
M. Vopálenský ◽  
P. Beneš ◽  
...  
Keyword(s):  
High Resolution ◽  
Single Photon ◽  
Photon Counting ◽  
Ct Imaging ◽  
Micro Ct ◽  
Large Area ◽  
Single Photon Counting ◽  
X Ray ◽  
Photon Counting Detector ◽  
Fibrin Scaffold

scholarly journals Synchrotron radiation X-ray tomographic microscopy (SRXTM) of brachiopod shell interiors for taxonomy: Preliminary report

2010 ◽  
pp. 109-117 ◽  
Author(s):  
Neda Motchurova-Dekova ◽  
David Harper
Keyword(s):  
Synchrotron Radiation ◽  
Three Dimensional ◽  
X Rays ◽  
X Ray ◽  
Fine Grained ◽  
Internal Structures ◽  
Efficient Alternative ◽  
Micro Tomography ◽  
Light Beams ◽  
Non Destructive

Synchrotron radiation X-ray tomographic microscopy (SRXTM) is a non-destructive technique for the investigation and visualization of the internal features of solid opaque objects, which allows reconstruction of a complete three-dimensional image of internal structures by recording of the differences in the effects on the passage of waves of energy reacting with those structures. Contrary to X-rays, produced in a conventional X-ray tube, the intense synchrotron light beams are sharply focused like a laser beam. We report encouraging results from the use of SRXTM for purely taxonomic purposes in brachiopods: an attempt to find a non-destructive and more efficient alternative to serial sectioning and several other methods of dissection together with the non-destructive method of X-ray computerised micro-tomography. Two brachiopod samples were investigated using SRXTM. In ?Rhynchonella? flustracea it was possible to visualise the 3D shape of the crura and dental plates. In Terebratulina imbricata it was possible to reveal the form of the brachidium. It is encouraging that we have obtained such promising results using SRXTM with our very first two fortuitous samples, which had respectively fine-grained limestone and marl as infilling sediment, in contrast to the discouraging results communicated to us by some colleagues who have tested specimens with such infillings using X-ray micro-tomography. In future the holotypes, rare museum specimens or delicate Recent material may be preferentially subjected to this mode of analysis.

Evaluation and comparison of a CdTe based photon counting detector with an energy integrating detector for X-ray phase sensitive imaging of breast cancer

2021 ◽  
pp. 1-13
Author(s):  
Muhammad U. Ghani ◽  
Farid H. Omoumi ◽  
Xizeng Wu ◽  
Laurie L. Fajardo ◽  
Bin Zheng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Spatial Resolution ◽  
Standard Dose ◽  
Photon Counting ◽  
High Energy ◽  
Edge Enhancement ◽  
X Ray ◽  
Photon Counting Detector ◽  
Phase Sensitive ◽  
Observer Studies

PURPOSE: To compare imaging performance of a cadmium telluride (CdTe) based photon counting detector (PCD) with a CMOS based energy integrating detector (EID) for potential phase sensitive imaging of breast cancer. METHODS: A high energy inline phase sensitive imaging prototype consisting of a microfocus X-ray source with geometric magnification of 2 was employed. The pixel pitch of the PCD was 55μm, while 50μm for EID. The spatial resolution was quantitatively and qualitatively assessed through modulation transfer function (MTF) and bar pattern images. The edge enhancement visibility was assessed by measuring edge enhancement index (EEI) using the acrylic edge acquired images. A contrast detail (CD) phantom was utilized to compare detectability of simulated tumors, while an American College of Radiology (ACR) accredited phantom for mammography was used to compare detection of simulated calcification clusters. A custom-built phantom was employed to compare detection of fibrous structures. The PCD images were acquired at equal, and 30% less mean glandular dose (MGD) levels as of EID images. Observer studies along with contrast to noise ratio (CNR) and signal to noise ratio (SNR) analyses were performed for comparison of two detection systems. RESULTS: MTF curves and bar pattern images revealed an improvement of about 40% in the cutoff resolution with the PCD. The excellent spatial resolution offered by PCD system complemented superior detection of the diffraction fringes at boundaries of the acrylic edge and resulted in an EEI value of 3.64 as compared to 1.44 produced with EID image. At MGD levels (standard dose), observer studies along with CNR and SNR analyses revealed a substantial improvement of PCD acquired images in detection of simulated tumors, calcification clusters, and fibrous structures. At 30% less MGD, PCD images preserved image quality to yield equivalent (slightly better) detection as compared to the standard dose EID images. CONCLUSION: CdTe-based PCDs are technically feasible to image breast abnormalities (low/high contrast structures) at low radiation dose levels using the high energy inline phase sensitive imaging technique.

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