Improvement of lymphocyte resistance against H2O2-induced DNA damage in Sprague–Dawley rats after eight weeks of a wild blueberry (Vaccinium angustifolium)-enriched diet

Author(s):  
Cristian Del Bo’ ◽  
Daniela Martini ◽  
Stefano Vendrame ◽  
Patrizia Riso ◽  
Salvatore Ciappellano ◽  
...  
2009 ◽  
Vol 111 (1) ◽  
pp. 64-71 ◽  
Author(s):  
Xinzhu Pu ◽  
Lisa M. Kamendulis ◽  
James E. Klaunig

Andrologia ◽  
2014 ◽  
Vol 47 (5) ◽  
pp. 568-578 ◽  
Author(s):  
B. Vijaya Bharathi ◽  
G. Jaya Prakash ◽  
K. M. Krishna ◽  
C. H. Ravi Krishna ◽  
T. Sivanarayana ◽  
...  

1984 ◽  
Vol 3 (2) ◽  
pp. 207-216
Author(s):  
Douglas E. Brash ◽  
Cheng M. Su ◽  
Hani A. Nabi ◽  
Kathleen S. Reuter ◽  
Judith Ortman ◽  
...  

Quantitative dose response measurements of diethylnitrosamine-and dibenzylnitrosamine-induced DNA single-strand breaks plus alkali-labile bonds (SSB + ALB) (single-strand breaks, apurinic/apyrimidinic sites, and phosphotriesters) were performed on samples of 100,000 nuclei from Sprague-Dawley rats. Twenty-four hours after diethylnitrosamine injection, there were no SSB + ALB in brain (nontarget), SSB + ALB in kidney (target), and SSB + ALB in liver (target only after partial hepatectomy, tumor promoters, or chronic administration). Seven days after diethylnitrosamine injection, liver SSB + ALB had declined. The noncarcinogenic diethylnitrosamine analog, dibenzylnitrosamine, induced no SSB + ALB at 6 hours or 7 days postinjection. Induction of DNA damage, therefore, correlates well with target organ specificity of tumorigenesis when specificity is broadened to include those organs that exhibit tumors only when DNA damage is followed by additional treatments.


2017 ◽  
Vol 274 ◽  
pp. 8-19 ◽  
Author(s):  
Jayaraman Krishnaraj ◽  
Jaganathan Kowshik ◽  
Robin Sebastian ◽  
Sathees C. Raghavan ◽  
Siddavaram Nagini

2013 ◽  
Vol 38 (6) ◽  
pp. 937-946 ◽  
Author(s):  
Ilseob Shim ◽  
Gyun-Baek Seo ◽  
Eunha Oh ◽  
Mimi Lee ◽  
Jung-Taek Kwon ◽  
...  

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