Impact of small fractions of abnormal erythrocytes on blood rheology

The integrated response of the human proteome to re-entry g-loads following long-term space missions was studied in 13 male cosmonauts at the age of 44 ± 6 years. Examination at the landing site discovered local petechial hemorrhages into soft tissues of the back and lower legs. The paper presents a new approach to evaluation of petechia and soft tissue hemorrhages in cosmonauts on return to Earth. Proteomic analysis was performed with the use of LC-MS. Bioinformation analysis was made using Perseus, PubMed, Uniprot and ANDSystem software. Nine out of 19 significantly different (p < 0.05) proteins were related to vascular injuries directly. We described proteins with a primarily protecting effect against endothelial cells apoptosis and augmentation of vascular permeability, proteins that are responsible for blood rheology and proteins antagonistic to the main triggers of ischeamia-reperfusion injuries of the lungs, liver and other parenchymal organs.

Download Full-text

Blood rheology in acute anterior ischemic optic neuropathy

Clinical Hemorheology and Microcirculation ◽

10.3233/ch-1991-11608 ◽

1991 ◽

Vol 11 (6) ◽

pp. 623-634 ◽

Cited By ~ 1

Author(s):

B. Bertram ◽

A. Hoberg ◽

O. Arend ◽

S. Wolf ◽

F. Jung ◽

...

Keyword(s):

Optic Neuropathy ◽

Blood Rheology ◽

Anterior Ischemic Optic Neuropathy ◽

Ischemic Optic Neuropathy

Download Full-text

Mathematical Models for Some Aspects of Blood Microcirculation

Symmetry ◽

10.3390/sym13061020 ◽

2021 ◽

Vol 13 (6) ◽

pp. 1020

Author(s):

Angiolo Farina ◽

Antonio Fasano ◽

Fabio Rosso

Keyword(s):

Blood Flow ◽

Mathematical Models ◽

Red Blood Cells ◽

Blood Cells ◽

Blood Rheology ◽

Small Class ◽

Small Vessels ◽

Blood Microcirculation ◽

Peculiar Behavior

Blood rheology is a challenging subject owing to the fact that blood is a mixture of a fluid (plasma) and of cells, among which red blood cells make about 50% of the total volume. It is precisely this circumstance that originates the peculiar behavior of blood flow in small vessels (i.e., roughly speaking, vessel with a diameter less than half a millimeter). In this class we find arteriolas, venules, and capillaries. The phenomena taking place in microcirculation are very important in supporting life. Everybody knows the importance of blood filtration in kidneys, but other phenomena, of not less importance, are known only to a small class of physicians. Overviewing such subjects reveals the fascinating complexity of microcirculation.

Download Full-text

Microparticle blood analogue suspension matching blood rheology

Soft Matter ◽

10.1039/d1sm00106j ◽

2021 ◽

Author(s):

Joao Carneiro ◽

Rui Lima ◽

Joao Campos ◽

Joao Miranda

Keyword(s):

Blood Rheology ◽

Safety Issues

The handling of blood in vitro is demanding because of ethical, economical and safety issues. Although several Newtonian and non-Newtonian blood analogues are found in the literature, few studies use...

Download Full-text