Gold nanoparticle-based nanobiosensor for biomedical application

2018 ◽  
Vol 44 ◽  
pp. S96
Author(s):  
S.J. Sim
2012 ◽  
Vol 23 (3) ◽  
pp. 399-408 ◽  
Author(s):  
Simon Guerrero ◽  
José Raul Herance ◽  
Santiago Rojas ◽  
Juan F. Mena ◽  
Juan Domingo Gispert ◽  
...  

2012 ◽  
Vol 529 ◽  
pp. 301-305
Author(s):  
Dong Yin Zhang ◽  
Jian Peng Xue ◽  
Jun Mei Tian ◽  
Jing Jin ◽  
Jie Cao ◽  
...  

Matriptase is a type II transmembrane serine protease highly expressed on the surface of tumor cells and participated in a range of human cancers including those of the breast, cervix, ovaries, prostate, colon and gastrointestinal tract. In this study, we developed a new matriptase detection probe with gold nanoparticles (AuNPs). A fluorescence dye was attached to AuNP surface through the bridge of peptide substrate (GRQSRAC). The fluorescence was quenched due to the fluorescence resonance energy transfer (FRET) between AuNP and the fluorescence dye. The fluorescence recovery properties were confirmed by dithiothreitol in vitro. The result of in vitro cell research indicates that the gold nanoparticle probe is sensitive and specificitive for the detection of matriptase expression in early tumor and has great potential in biomedical application.


RSC Advances ◽  
2014 ◽  
Vol 4 (53) ◽  
pp. 27811-27819 ◽  
Author(s):  
Kenji Kono ◽  
Keishi Takeda ◽  
Xiaojie Li ◽  
Eiji Yuba ◽  
Atsushi Harada ◽  
...  

Stimuli-sensitive dendrimers of a new type were developed through dual functionalization of polyamidoamine (PAMAM) dendrimers with temperature-sensitive surface modification using propoxy diethylene glycol (PDEG) and Au nanoparticle (AuNP) loading.


2020 ◽  
Vol E103.C (2) ◽  
pp. 62-65
Author(s):  
Yoshinao MIZUGAKI ◽  
Makoto MORIBAYASHI ◽  
Tomoki YAGAI ◽  
Masataka MORIYA ◽  
Hiroshi SHIMADA ◽  
...  

2000 ◽  
Vol 28 (3-4) ◽  
pp. 481-485 ◽  
Author(s):  
Alessandro Mantini ◽  
Corrado Di Natale ◽  
Antonella Macagnano ◽  
Roberto Paolesse ◽  
Alessandro Finazzi-Agro ◽  
...  

2020 ◽  
Vol 3 (3) ◽  
Author(s):  
Hemalatha D ◽  
Saraswath S

In material science, green method for synthesis of nanomaterials is feasible, cheaper and eco-friendly protocol. To accomplish this phenomenon, present study was aimed to synthesize Copper oxide nanoparticles using leaf extract of Aloevera with two different precursors CuCl2.2H2O (Cupric chloride) and CuSo4.5H2O (Cupric sulfate). The extraction of Aloevera is employed as reducing and stabilizing agent for this synthesis.Copper oxide Nanoparticles is effective use of biomedical application due to their antibacterial function. The synthesized Copper oxide nanoparticles were characterized by X-Ray Diffraction Spectroscopy (XRD), Energy Dispersive Spectroscopy (EDX), FourierTransform Infrared Spectroscopy (FT- IR) and Scanning Electron Microscope(SEM). XRD studies reveal the crystallographic nature of Copper oxide nanoparticles. Furthermore the Copper oxide nanoparticles have good Antibacterial activity against both gram negative (E.Coli, Klebsiella pneumonia) and gram positive (Bacillus cereus, Staphylococcus aureus)bacteria.


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