Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: Its prevention by melatonin, Vitamin E, and Vitamin C

2006 ◽  
Vol 392 (1-2) ◽  
pp. 1-4 ◽  
Author(s):  
Francisco Martínez-Cruz ◽  
Carmen Osuna ◽  
Juan M. Guerrero
Keyword(s):  
Vitamin E ◽  
Vitamin C ◽  
Rat Brain ◽  
Mitochondrial Damage ◽  
Rat Brain And Liver

scholarly journals REM SLEEP DEPRIVATION-INDUCED OXIDATIVE STRESS AND ITS ATTENUATION BY TEPHROSIA PURPUREA (L.,) IN DISCRETE REGIONS OF RAT BRAIN

2018 ◽  
Vol 11 (5) ◽  
pp. 308
Author(s):  
Prakash Selvaraj ◽  
Annadurai Shanmuganathan ◽  
Saravanan Selvaraj ◽  
Babukumar Mani ◽  
Sakthivel Govindaraj ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Vitamin E ◽  
Vitamin C ◽  
Sleep Deprivation ◽  
Rat Brain ◽  
Rem Sleep ◽  
Rem Sleep Deprivation ◽  
Tephrosia Purpurea ◽  
Wide Range ◽  
Induced Changes

Objective: The aim of this study is to assess the antioxidant activity of Tephrosia purpurea (TP) in 72 h REM sleep deprivation (RSD). Nowadays, plants are used as therapeutic agents in the wide range of clinical applications. The present investigation is focused on the antioxidant activity of the ethanolic extract of TP on 72 h RSD induced changes in discrete regions of rat brain.Methods: In this study, the plant (leaf) sample collected and ethanolic extraction were done using Soxhlet apparatus. Five groups of Wistar strain male albino rats were used in this study. Each group comprises 6 rats and multiple platform models used for RSD. The values were statistically analyzed using one-way analysis of variance followed by Tukey’s post hoc test for multiple comparison methods. The significance level was kept at p<0.05. The 72 h RSD-induced changes in discrete regions were investigated and verified by measuring the activity of superoxide dismutase (SOD), lipid peroxidation (LPO), catalase (CAT), glutathione peroxidase (GPx), levels of reduced glutathione (GSH), Vitamin C, and Vitamin E in different regions of the rat brain, and plasma corticosterone level.Results: This study confirmed that the leaf extract of TP effectively normalized the increased corticosterone, LPO, SOD, CAT, GPx, and decreased GSH, Vitamin C, and Vitamin E levels as a result of 72 h RSD exposure.Conclusion: The plant examined and possessed remarkable antioxidant activity; hence, the isolation of compounds from this plant leaves may develop a novel and natural phytomedicine for stress-induced diseases.

Alteration of Δ-6 desaturase by vitamin E in rat brain and liver

1992 ◽  
Vol 145 (1) ◽  
pp. 19-22 ◽  
Author(s):  
S. Despret ◽  
L. Dinh ◽  
M. Clément ◽  
J.M. Bourre
Keyword(s):  
Vitamin E ◽  
Rat Brain ◽  
Rat Brain And Liver

scholarly journals Enzymic synthesis of ether types of choline and ethanolamine phosphoglycerides by microsomal fractions from rat brain and liver

1977 ◽  
Vol 18 (1) ◽  
pp. 53-58
Author(s):  
A Radominska-Pyrek ◽  
J Strosznajder ◽  
Z Dabrowiecki ◽  
G Goracci ◽  
T Chojnacki ◽  
...  
Keyword(s):  
Rat Brain ◽  
Enzymic Synthesis ◽  
Ethanolamine Phosphoglycerides ◽  
Rat Brain And Liver
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