Faculty Opinions recommendation of Long-term use of supplemental multivitamins, vitamin C, vitamin E, and folate does not reduce the risk of lung cancer.

2008 ◽  
Author(s):  
Patrick Nana-Sinkam
Keyword(s):  
Lung Cancer ◽  
Vitamin E ◽  
Vitamin C

scholarly journals Long-Term Use of Supplemental Multivitamins, Vitamin C, Vitamin E, and Folate Does Not Reduce the Risk of Lung Cancer

2008 ◽  
Vol 177 (5) ◽  
pp. 524-530 ◽  
Author(s):  
Christopher G. Slatore ◽  
Alyson J. Littman ◽  
David H. Au ◽  
Jessie A. Satia ◽  
Emily White
Keyword(s):  
Lung Cancer ◽  
Vitamin E ◽  
Vitamin C

scholarly journals ROLE OF VITAMIN C AND VITAMIN E ON HYPERTENSION

2019 ◽  
pp. 95-98 ◽  
Author(s):  
SANTHOSHAKUMARI TMJ ◽  
MATHIVANAN J ◽  
JEYALAKSHMI J
Keyword(s):  
Vitamin E ◽  
Vitamin C ◽  
Oral Vitamin ◽  
Test Analysis ◽  
Oral Supplementation ◽  
Clinical Events ◽  
Significant Difference ◽  
Group 2 ◽  
Vitamin E Supplementation

Objective: Both Vitamin C and Vitamin E supplementation were associated with reduction in blood pressure (BP) in observational studies, although, results of clinical trials are inconsistent. The objective of our study is to conduct a clinical trial to observe the effects of oral supplementation of Vitamin C and Vitamin E on BP. Methods: About 60 non-teaching staffs of our college with systolic BP more than 130 mmHg and diastolic BP more than 90 mmHg were taken as subjects and divided into two groups. Initial BP and BP after oral Vitamin C, 500 mg/day for a period of 12weeks to Group 1 and initial BP and BP after oral Vitamin E, 200 IU/day, for a period of 12 weeks to Group 2 were recorded. Results: Statistical analysis was done by paired t-test, analysis of variance (ANOVA), and least significant difference (LSD) tests. *p<0.05 was considered statistically significant. Systolic 2 and diastolic 2 – after 3 months of supplementation showed 0.161 and 0.161 which is not significant. ANOVA and LSD tests show no significant results. Conclusion: Long-term trials on the effects of Vitamin C and Vitamin E supplementation on BP and clinical events are needed.

scholarly journals Efficacy of Vitamin C and Vitamin E as an add on therapy in diabetic foot ulcer and red blood cell morphology as a biomarker of oxidative stress: a randomized, open label, comparative pilot study

2018 ◽  
Vol 7 (3) ◽  
pp. 548
Author(s):  
Vasanthi B. ◽  
Ainsy Goldlin T. J.
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Vitamin E ◽  
Vitamin C ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Control Group ◽  
Study Group

Background: Diabetes mellitus is a major cause of increased morbidity and mortality in developing countries. Foot ulcer is one of the long term complications of diabetes. Oxidative stress plays a major role in pathogenesis of diabetes mellitus and its long term complications. Impaired wound healing in diabetic individuals is due to ischemia and hypoxia occurring as a consequence of oxidative stress. Vitamin C and E have antioxidant property. This study aims to assess their efficacy in healing of diabetic ulcer. Objective of the study was to evaluate the efficacy of Vitamin C and E in healing diabetic foot ulcer.Methods: 60 adult patients with diabetic foot ulcer were randomized to test and control groups (30 in each). Treatment period was 12 weeks + 4 weeks follow up per patient. After obtaining written informed consent, patients in test group received Vitamin C (500mg BD) and Vitamin E (400mg BD) for 12 weeks along with standard treatment for diabetes and antibiotics for foot ulcer.Results: At the end of 12 weeks, increase in healing of foot ulcer assessed by percent reduction of ulcer area in study group 72.50% than control group 39.67% (p<0.001) was observed. There was a significant reduction of fasting blood glucose, Oxidative stress induced damage to RBCs and BP in the study group compared to control group. No serious adverse effects occurred.Conclusions: Vitamin C and E reverse oxidative stress induced morphological changes in RBCs, improve anemia and increase blood flow to ulcer area. Hence they are highly effective in healing diabetic foot ulcer along with standard therapy. 

scholarly journals VITAMIN-ANTIOXIDANT HOMEOSTASIS DATA IN PATIENTS WITH LONG-TERM CONSEQUENCES AFTER MILD TRAUMATIC BRAIN INJURY

2020 ◽  
Vol 46 (3) ◽  
pp. 15
Author(s):  
Y. V. Lekomtseva
Keyword(s):  
Traumatic Brain Injury ◽  
Vitamin E ◽  
Brain Injury ◽  
Vitamin C ◽  
Mild Traumatic Brain Injury ◽  
Brain Injuries ◽  
Serum Vitamin ◽  
Secondary Brain Injury ◽  
Long Term Consequences

Introduction. Mild traumatic brain injury (mTBI) was reported to be the most frequent among other types of brain injuries and is the main reason for the disability in mid-life and middleaged people. It’s known that antioxidants can reduce oxidative stress, so, to prevent secondary brain injury modulating maintaining of long-term consequences after mTBI. Purpose of the study. This work was to study the serum vitamin E, C and A levels in the patients with long-term consequences after mTBI to explore their potential pathogenetic influence. Materials and methods. Sixty-seven patients with long-term consequences after mTBI were investigated with the mean age of 43,61 ± 8,24 years (18 women, 26,86% and 49 men, 73,14%) where the vitamin E, C and A contents were measured in sera by spectrophotometer method using standard protocols and reagents (Sigma, USA).  Results. In this work, it was found descending serum levels of all investigated vitaminantioxidants in almost all patients with longterm consequences after mTBI where the content of vitamins A (M ± s: 1,63 ± 1,56 mkM/l) and E (25,41 ± 0,93 mkM/l) had a tendency to decreasing without significant differences compare to controls. It was found the statistically significant decreased of vitamin C levels in the serum samples of our investigated patients when compared to controls (p < 0,05, t = 4,59, 95% CI 98,81 to 55,68) where in the main patient group, the medians of total vitamin C level was 30,57 ± 5,38 mkM/l vs 36,91 ± 5,22 mkM/l in controls. It was shown that the patients with long-term consequences after mild contusion in anamnesis (64,18%) had the prominent changes in the vitamin C content. Conclusion. The maintaining of long-term consequences of mTBI was accompanied by the vitamin-antioxidant dyshomeostasis such as decreasing of vitamin C serum level associated with a tendency to decreasing of vitamins A and E levels that may play the certain role in the pathogenesis. All these data are needed to be accounted into the consideration during the treatment of this patient category. Keywords: long-term consequences of mild traumatic brain injury, vitamin-antioxidant homeostasis.

scholarly journals Influence of vitamins C and E on the quality of cryopreserved semen Prochilodus brevis (Prochilodontidae, Teleostei)

2017 ◽  
Vol 38 (4Supl1) ◽  
pp. 2669
Author(s):  
Priscila Silva de Almeida-Monteiro ◽  
Mayara Setúbal Oliveira Araújo ◽  
Romulo Roberto Ribeiro Pinheiro ◽  
Júlia Trugilio Lopes ◽  
Yasmim Maia Ferreira ◽  
...  
Keyword(s):  
Vitamin E ◽  
Vitamin C ◽  
Deleterious Effect ◽  
Membrane Integrity ◽  
Sperm Cells ◽  
Second Stage ◽  
Sperm Membrane ◽  
Two Stages

Seminal cryopreservation allows the long-term conservation of gametes of various species, including endangered species, such as Prochilodus brevis. However, the application of this biotechnology can cause damage to sperm cells, reducing seminal quality. Thus, we have sought substances that minimize the damage caused by this process, such as antioxidants. Thus, this study aimed to evaluate the association between two cryoprotectants and two vitamins, in different concentrations, on the quality of cryopreserved semen of P. brevis. For cryopreservation, the experiment was performed in two stages. In the first stage, the semen of 10 animals was submitted to six different freezing means, coming from the combination of 5% glucose, two cryoprotectants (Dimethyl sulfoxide [DMSO] or Methyl glycol) and two vitamins (C or E to 0.0001 mg) for cryopreservation. In the second stage, semen samples of eight animals were diluted in 5% glucose and the best cryoprotectant found in the first stage, associated with three different concentrations of vitamins C or E (0.01, 0.001, and 0.0001 mg). In both steps, the in natura and post-thawed samples were submitted to kinetic analysis, morphology, and sperm membrane integrity. The cryopreserved semen with DMSO presented significantly higher results (p < 0.05) than that frozen with Methyl glycol, regardless of the vitamin used. The morphologically normal spermatozoa rate was higher (p < 0.05) in the vitamin-containing samples, however, vitamin E reduced sperm motility rates, independent of the cryoprotectant used. As for vitamin concentrations, higher motility rates were obtained when cryopreserved semen with 0.01 and 0.0001 mg of any of the vitamins. However, the higher concentration had a deleterious effect on the spermatic morphology of P. brevis. Therefore, the glucose associated with DMSO and the lower concentration of vitamin C provides good quality for the post-thawed semen of P. brevis.

Sign in / Sign up

Export Citation Format

Share Document