Testing the effects of transcranial direct current stimulation (tDCS) on the face inversion effect and the N170 event-related potentials (ERPs) component

2020 ◽  
Vol 143 ◽  
pp. 107470
Author(s):  
Ciro Civile ◽  
Emika Waguri ◽  
Samantha Quaglia ◽  
Brad Wooster ◽  
Adam Curtis ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Event Related Potentials ◽  
Inversion Effect ◽  
Face Inversion Effect ◽  
Direct Current Stimulation ◽  
Face Inversion ◽  
The Face ◽  
Related Potentials

scholarly journals Using transcranial Direct Current Stimulation (tDCS) to investigate why faces are and are not special

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ciro Civile ◽  
Samantha Quaglia ◽  
Emika Waguri ◽  
Maddy Ward ◽  
Rossy McLaren ◽  
...  
Keyword(s):  
Direct Current ◽  
Sham Group ◽  
Inversion Effect ◽  
Matching Task ◽  
Anodal Tdcs ◽  
Double Blind ◽  
Face Inversion Effect ◽  
Face Inversion ◽  
Subject Design ◽  
The Face

AbstractWe believe we are now in a position to answer the question, "Are faces special?" inasmuch as this applies to the face inversion effect (better performance for upright vs inverted faces). Using a double-blind, between-subject design, in two experiments (n = 96) we applied a specific tDCS procedure targeting the Fp3 area while participants performed a matching-task with faces (Experiment 1a) or checkerboards from a familiar prototype-defined category (Experiment 1b). Anodal tDCS eliminated the checkerboard inversion effect reliably obtained in the sham group, but only reduced it for faces (although the reduction was significant). Thus, there is a component to the face inversion effect that we are not affecting with a tDCS procedure that can eliminate the checkerboard inversion effect. We suggest that the reduction reflects the loss of an expertise-based component in the face inversion effect, and the residual is due to a face-specific component of that effect.

Modulating Effects of Transcranial Direct Current Stimulation on Event Related Potentials in a Motor Sequence Task

2014 ◽  
Vol 7 (2) ◽  
pp. e7
Author(s):  
Stephanie Rohrig ◽  
Devin Adair ◽  
Aleksandra Kaszowska ◽  
Pejman Sehatpour ◽  
Daniel C. Javitt
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Event Related Potentials ◽  
Motor Sequence ◽  
Direct Current Stimulation ◽  
Related Potentials

Transcranial Direct Current Stimulation Combined With Cognitive Training Induces Response Inhibition Facilitation Through Distinct Neural Responses According to the Stimulation Site: A Follow-up Event-Related Potentials Study

2020 ◽  
pp. 155005942095896
Author(s):  
Clémence Dousset ◽  
Anaïs Ingels ◽  
Elisa Schröder ◽  
Laura Angioletti ◽  
Michela Balconi ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Cognitive Rehabilitation ◽  
Response Times ◽  
Inferior Frontal Gyrus ◽  
Training Session ◽  
Event Related Potentials ◽  
Stimulation Site ◽  
Direct Current Stimulation ◽  
Related Potentials

Objective We investigated whether the mid-term impact (1 week posttraining) of a “combined cognitive rehabilitation (CRP)/transcranial direct current stimulation (tDCS) program” on the performance of a Go/No-go task was enhanced compared with isolated CRP and whether it varied according to the stimulation site (right inferior frontal gyrus [rIFG] vs right dorsolateral prefrontal cortex [rDLPFC]). Methods A total of 150 healthy participants were assigned to (1) an Inhibition Training (IT) group, (2) a group receiving active tDCS over the rIFG in combination with IT (IT + IF), (3) a group receiving active tDCS over the rDLPFC in combination with IT (IT + DL), (4) a group receiving IT with sham tDCS (ITsham), and (5) a No-Training (NT) group to control for test-retest effects. Each group undertook 3 sessions of a Go/No-go task concomitant with the recording of event-related potentials (T0, before training; T1, at the end of a 4-day training session [20 minutes each day]; T2, 1 week after T1). Results With the exception of the NT participants, all the groups exhibited improved performances at T2. The IT + DL group exhibited the best improvement profile, indexed by faster response times (RTs) (T0 > T1 = T2), with a reduced rate of errors at the posttraining sessions compared with both T0 and T1. This “inhibitory learning effect” was neurophysiologically indexed by shorter No-go N2d latencies and enhanced No-go P3d amplitudes. Conclusion CRP combined with active tDCS over the rDLPFC appears to be optimal for boosting long-term (one week) inhibitory skills as it induced specific and robust neural changes.

scholarly journals The effect of scrambling upright and inverted faces on the N170

2018 ◽  
Vol 71 (11) ◽  
pp. 2464-2476 ◽  
Author(s):  
Ciro Civile ◽  
Heike Elchlepp ◽  
Rossy McLaren ◽  
Carl Michael Galang ◽  
Aureliu Lavric ◽  
...  
Keyword(s):  
Present Experiment ◽  
Event Related Potentials ◽  
Inversion Effect ◽  
Upright Orientation ◽  
Face Inversion Effect ◽  
Configural Information ◽  
The Face ◽  
Related Potentials ◽  
Stimulus Features ◽  
The Impact

The face inversion effect refers to a decrement in performance when we try to recognise familiar faces turned upside down (inverted), compared with familiar faces presented in their usual (upright) orientation. Recently, we have demonstrated that the inversion effect can also be found with checkerboards drawn from prototype-defined categories when the participants have been trained with these categories, suggesting that factors such as expertise and the relationships between stimulus features may be important determinants of this effect. We also demonstrated that the typical inversion effect on the N170 seen with faces is found with checkerboards, suggesting that modulation of the N170 is a marker for disruption in the use of configural information. In the present experiment, we first demonstrate that our scrambling technique greatly reduces the inversion effect in faces. Following this, we used Event-Related Potentials ( ERPs) recorded while participants performed an Old/New recognition study on normal and scrambled faces presented in both upright and inverted orientations to investigate the impact of scrambling on the N170. We obtained the standard robust inversion effect for normal faces: The N170 was both larger and delayed for normal inverted faces as compared with normal upright faces, whereas a significantly reduced inversion effect was recorded for scrambled faces. These results show that the inversion effect on the N170 is greater for normal compared with scrambled faces, and we interpret the smaller effect for scrambled faces as being due to the reduction in expertise for those faces consequent on scrambling.

scholarly journals Case Report: Improving Verbal Retrieval Deficits With High Definition Transcranial Direct Current Stimulation Targeting the Pre-Supplementary Motor Area in a Patient With Chronic Traumatic Brain Injury

2021 ◽  
Vol 12 ◽  
Author(s):  
Hsueh-Sheng Chiang ◽  
Scott Shakal ◽  
Sven Vanneste ◽  
Michael Kraut ◽  
John Hart
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Supplementary Motor Area ◽  
Event Related Potentials ◽  
Motor Area ◽  
High Definition ◽  
Direct Current Stimulation ◽  
Related Potentials

We report a patient who has cognitive sequalae including verbal retrieval deficits after severe traumatic brain injury (TBI). The cortico-caudate-thalamic circuit involving the pre-Supplementary Motor Area (pre-SMA) has been proposed to underlie verbal retrieval functions. We hypothesized that High Definition-transcranial Direct Current Stimulation (HD-tDCS) targeting the pre-SMA would selectively modulate this circuit to remediate verbal retrieval deficits. After the patient underwent 10 sessions of 20 min of 1 mA HD-tDCS targeting the pre-SMA, we documented significant improvements for verbal fluency and naming, and for working memory and executive function tasks that involve the frontal lobes. The effects persisted for up to 14 weeks after completion of HD-tDCS treatment. We also demonstrated normalization of the event-related potentials suggesting modulation of the underlying neural circuit. Our study implicates that region-specific non-invasive brain stimulation, such as HD-tDCS, serves as a potential individualized therapeutic tool to treat cognitive deficits by inducing longer-lasting neuroplasticity even in the chronic phase of TBI.

scholarly journals Effects of Transcranial Direct Current Stimulation (tDCS) on Go/NoGo Performance Using Food and Non-Food Stimuli in Patients with Prader–Willi Syndrome

2021 ◽  
Vol 11 (2) ◽  
pp. 250
Author(s):  
Albert B. Poje ◽  
Ann Manzardo ◽  
Kathleen M. Gustafson ◽  
Ke Liao ◽  
Laura E. Martin ◽  
...  
Keyword(s):  
Direct Current ◽  
Behavioral Problems ◽  
Transcranial Direct Current Stimulation ◽  
Genetic Disorder ◽  
Event Related Potentials ◽  
Prader Willi Syndrome ◽  
Feeding Difficulties ◽  
Direct Current Stimulation ◽  
Positive Effects ◽  
Related Potentials

Prader–Willi syndrome (PWS) is a neurodevelopmental genetic disorder characterized by multiple system involvement with hypotonia, poor suck with feeding difficulties, growth and other hormone deficiencies, intellectual disability, and behavioral problems with childhood onset of hyperphagia resulting in obesity, if not externally controlled. Transcranial direct current stimulation (tDCS) has been increasingly shown to modulate cognitive and behavioral processes in children and adults, including food-intake behaviors in patients with PWS. This study further reports the positive effects of brief tDCS sessions on Go/NoGo task performance involving food and non-food stimuli images, alterations in N2 brain amplitude, and genetic subgroup differences (maternal disomy 15, UPD; 15q11-q13 deletion, DEL) before and after tDCS as assessed by event-related potentials (ERPs) in 10 adults with PWS. The results indicate a group effect on baseline NoGo N2 amplitude in PWS patients with DEL vs UPD (p =0.046) and a decrease in NoGo N2 amplitude following tDCS (p = 0.031). Our tDCS approach also demonstrated a trend towards decreased response time. Collectively, these results replicate and expand prior work highlighting neurophysiological differences in patients with PWS according to genetic subtype and demonstrate the feasibility in examining neuromodulatory effects of tDCS on information processing in this patient population to stimulate additional research and treatment.

scholarly journals The Influence of Pre-Supplementary Motor Area Targeted High-Definition Transcranial Direct Current Stimulation on Inhibitory Control

2020 ◽  
Author(s):  
Bambi L. DeLaRosa ◽  
Jeffrey S. Spence ◽  
Michael A. Motes ◽  
Wing To ◽  
Sven Vanneste ◽  
...  
Keyword(s):  
Inhibitory Control ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Supplementary Motor Area ◽  
Event Related Potentials ◽  
Motor Area ◽  
High Definition ◽  
Direct Current Stimulation ◽  
Related Potentials ◽  
Cathodal Stimulation

AbstractThe neural underpinnings of inhibitory control, an executive cognitive control function, has been a topic of interest for several decades due to both its clinical significance and the maturation of cognitive science disciplines. Behavioral, imaging, and electrophysiological studies suggest that the pre-supplementary motor area (preSMA) serves as a primary hub in a network of regions engaged in inhibition. High-definition transcranial direct current stimulation (HD-tDCS) allows us to modulate neural function to assess cortical contribution to cognitive functioning. The present study targeted HD-tDCS modulation of preSMA to affect inhibition. Participants were randomly assigned to receive 20 min of Sham, Anodal, or Cathodal stimulation prior to completing a semantically cued go/nogo task while electroencephalography (EEG) data were recorded. Both anodal and cathodal stimulation improved inhibitory performance as measured by faster reaction times and increased (greater negative) N2 event-related potentials (ERPs). In contrast, the Sham group did not show such changes. We did not find support for the anodal/cathodal dichotomy for HD neural stimulation. These findings constitute an early investigation into role of the preSMA in inhibitory control and in exploring application of HD-tDCS to the preSMA in order to improve inhibitory control.

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