Cognitive components in mice and humans: Combining genetics and touchscreens for medical translation

2013 ◽  
Vol 105 ◽  
pp. 13-19 ◽  
Author(s):  
Jess Nithianantharajah ◽  
Seth G.N. Grant
2019 ◽  
Vol 28 (4) ◽  
pp. 834-842
Author(s):  
Harini Vasudevan ◽  
Hari Prakash Palaniswamy ◽  
Ramaswamy Balakrishnan

Purpose The main purpose of the study is to explore the auditory selective attention abilities (using event-related potentials) and the neuronal oscillatory activity in the default mode network sites (using electroencephalogram [EEG]) in individuals with tinnitus. Method Auditory selective attention was measured using P300, and the resting state EEG was assessed using the default mode function analysis. Ten individuals with continuous and bothersome tinnitus along with 10 age- and gender-matched control participants underwent event-related potential testing and 5 min of EEG recording (at wakeful rest). Results Individuals with tinnitus were observed to have larger N1 and P3 amplitudes along with prolonged P3 latency. The default mode function analysis revealed no significant oscillatory differences between the groups. Conclusion The current study shows changes in both the early sensory and late cognitive components of auditory processing. The change in the P3 component is suggestive of selective auditory attention deficit, and the sensory component (N1) suggests an altered bottom-up processing in individuals with tinnitus.


2020 ◽  
Vol 51 (4) ◽  
pp. 1172-1186
Author(s):  
Carolina Beita-Ell ◽  
Michael P. Boyle

Purpose The purposes of this study were to examine the self-efficacy of school-based speech-language pathologists (SLPs) in conducting multidimensional treatment with children who stutter (CWS) and to identify correlates of self-efficacy in treating speech-related, social, emotional, and cognitive domains of stuttering. Method Three hundred twenty randomly selected school-based SLPs across the United States responded to an online survey that contained self-efficacy scales related to speech, social, emotional, and cognitive components of stuttering. These ratings were analyzed in relation to participants' beliefs about stuttering treatment and their comfort level in treating CWS, perceived success in therapy, and empathy levels, in addition to their academic and clinical training in fluency disorders as well as demographic information. Results Overall, SLPs reported moderate levels of self-efficacy on each self-efficacy scale and on a measure of total self-efficacy. Significant positive associations were observed between SLPs' self-efficacy perceptions and their comfort level in treating CWS, self-reported success in treatment, beliefs about the importance of multidimensional treatment, and self-reported empathy. There were some discrepancies between what SLPs believed was important to address in stuttering therapy and how they measured success in therapy. Conclusions Among school-based SLPs, self-efficacy for treating school-age CWS with a multidimensional approach appears stronger than previously reported; however, more progress in training and experience is needed for SLPs to feel highly self-efficacious in these areas. Continuing to improve clinician self-efficacy for stuttering treatment through improved academic training and increased clinical experiences should remain a high priority in order to enhance outcomes for CWS. Supplemental Material https://doi.org/10.23641/asha.12978194


2014 ◽  
Vol 45 (1) ◽  
pp. 15-30 ◽  
Author(s):  
Maya Machunsky ◽  
Thorsten Meiser

This research investigated whether relative ingroup prototypicality (i.e., the tendency to perceive one’s own ingroup as more prototypical of a superordinate category than the outgroup) can result from a prototype-based versus exemplar-based mental representation of social categories, rather than from ingroup membership per se as previously suggested by the ingroup projection model. Experiments 1 and 2 showed that a prototype-based group was perceived as more prototypical of a superordinate category than an exemplar-based group supporting the hypothesis that an intergroup context is not necessary for biased prototypicality judgments. Experiment 3 introduced an intergroup context in a minimal-group-like paradigm. The findings demonstrated that both the kind of cognitive representation and motivational processes contribute to biased prototypicality judgments in intergroup settings.


2002 ◽  
Vol 21 (2) ◽  
pp. 7-20 ◽  
Author(s):  
Peter M. Clarkson ◽  
Craig Emby ◽  
Vanessa W.-S. Watt

The outcome effect occurs where an evaluator, who has knowledge of the outcome of a judge's decision, assesses the quality of the judgment of that decision maker. If the evaluator has knowledge of a negative outcome, then that knowledge negatively influences his or her assessment of the ex ante judgment. For instance, jurors in a lawsuit brought against an auditor for alleged negligence are informed of an undetected fraud, even though an unqualified opinion was issued. This paper reports the results of an experiment in an applied audit judgment setting that examined methods of mitigating the outcome effect by means of instructions. The results showed that simply instructing or warning the evaluator about the potential biasing effects of outcome information was only weakly effective. However, instructions that stressed either (1) the cognitive nonnormativeness of the outcome effect or (2) the seriousness and gravity of the evaluation ameliorated the effect significantly. From a theoretical perspective, the results suggest that there may both motivational and cognitive components to the outcome effect. In all, the findings suggest awareness of the outcome effect and use of relatively nonintrusive instructions to evaluators may effectively counteract the potential for the outcome bias.


Author(s):  
Meng Ji ◽  
Kristine Sørensen ◽  
Pierrette Bouillon

Healthcare translation provides a useful and powerful intervention tool to facilitate the engagement with migrants with diverse language, cultural, and health literacy backgrounds. The development of culturally effective and patient-oriented healthcare translation resources has become increasingly pressing. In this chapter, the authors explore, firstly, patient-focused and culturally effective healthcare and medical translation methodologies by integrating insights from health literacy research and corpus-based textual readability evaluation and, secondly, user-oriented criteria which can be used in the development and evaluation of new medical interpreting technologies with a view to enhancing the usability among patients from refugee, migrant, or other socioeconomically disadvantaged populations.


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