Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis

2010 ◽  
Vol 30 (9) ◽  
pp. 601-606 ◽  
Author(s):  
Reza Farid ◽  
Zahra Rezaieyazdi ◽  
Zahra Mirfeizi ◽  
Mohamad Reza Hatef ◽  
Mahyar Mirheidari ◽  
...  
2019 ◽  
Vol 7 (4) ◽  
pp. 536-542 ◽  
Author(s):  
Nerdy Nerdy ◽  
Kiking Ritarwan

BACKGROUND: The Passion Fruit (Passiflora sp.) that grows in the Indonesian region generally has three varieties, namely purple passion fruit (Passiflora edulis Sims.), red passion fruit (Passiflora ligularis Juss.), and yellow passion fruit (Passiflora verrucifera Lindl.). The passion fruit peel is an economic waste that has not been utilised optimally, but has many efficacious phytochemical contents. AIM: The objectives of this research are to examine scientifically hepatoprotective activity (with paracetamol-induced hepatotoxic) and nephroprotective activity (with gentamicin-induced nephrotoxic) from three varieties of the passion fruit (purple passion fruit peel extract, red passion fruit peel extract and yellow passion fruit peel extract) in the albino rat (Rattus norvegicus). METHODS: Three varieties of passion fruit peels were extracted by maceration method. The experimental animals used were the albino rat (Rattus norvegicus). Hepatoprotective activity was done by the liver biochemical (alanine transaminase and aspartate transaminase) analysis with paracetamol (hepatotoxic compound) induced after 10 days of treatment with extract. Nephroprotective activity was done by the kidney biochemical (urea and creatinine) analysis with gentamicin (nephrotoxic compound) induced after 10 days of treatment with extract. RESULTS: The hepatoprotective activity for positive control was similar to the 250 mg of purple passion fruit peel extract per kg of body weight, 250 mg of red passion fruit peel extract per kg of body weight, and 500 mg of yellow passion fruit peel extract per kg of body weight. The nephroprotective activity for positive control (50 mg of silymarin per kg of body weight) was similar to the 250 mg of purple passion fruit peel extract per kg of body weight, 500 mg of red passion fruit peel extract per kg of body weight, and 500 mg of yellow passion fruit peel extract per kg of body weight. CONCLUSIONS: The extracts were shown hepatoprotective activity and nephroprotective activity with a dose-dependent activity. The hepatoprotective activity and nephroprotective activity of purple passion fruit peel extract were the best compared to red passion fruit peel extract and yellow passion fruit peel extract.


2008 ◽  
Vol 121 (2) ◽  
pp. S221-S221
Author(s):  
R FARID ◽  
S ZIBADI ◽  
H RAFATPANAH ◽  
F JABBARI ◽  
R GHASEMI ◽  
...  

2008 ◽  
Vol 28 (3) ◽  
pp. 166-171 ◽  
Author(s):  
Ronald Ross Watson ◽  
Sherma Zibadi ◽  
Houshang Rafatpanah ◽  
Farahzad Jabbari ◽  
Ramin Ghasemi ◽  
...  

2013 ◽  
Vol 18 (3) ◽  
pp. 183-190 ◽  
Author(s):  
I. Naga Raju ◽  
K. Kodandarami Reddy ◽  
C. Krishna Kumari ◽  
E. Bhaskar Reddy ◽  
S. Dattatreya Rao ◽  
...  

The clinical efficacy of purple passion fruit peel extract (a flavonoid-rich dietary supplement) in reducing cardiovascular risk factors in adult type 2 diabetic subjects was investigated in a randomized, double-blind, placebo-controlled trial. Forty-one subjects were randomly assigned to receive a daily dose of purple passion fruit (220 mg) or a matched placebo for 16 weeks. Body mass index, blood pressure, fasting and postprandial blood glucose, glycated hemoglobin, and lipid profile were determined at baseline and at monthly intervals. A significant reduction in systolic blood pressure and fasting blood glucose was observed following administration of purple passion fruit ( P < .05). Purple passion fruit was well tolerated, and no adverse events were reported. These data suggest that purple passion fruit supplementation for 16 weeks in type 2 diabetics results in a significant reduction in systolic blood pressure and fasting blood glucose, indicating that purple passion fruit is safe and well tolerated by diabetics.


2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Sherma Zibadi ◽  
Pooya Moslemzadeh Tehrani ◽  
Satoru Moriguchi ◽  
Yinrong Lu ◽  
Lai Yeap Foo ◽  
...  

2019 ◽  
Vol 2 (1) ◽  
pp. 07-12
Author(s):  
Sony Eka Nugraha ◽  
Suryadi Achmad ◽  
Erly Sitompul

North Sumatera is one of the central areas of purple passion fruit production in Indonesia. Processing passion fruit into beverage products (passion fruit juice) produces peel  has not been utilized. The use of passion fruit skin needs to be studied so that it can be useful as a raw material for antibacterial drug preparations. The aim of this study was to determine the phytochemical constituent screening  and antibacterial activity of ethyl acetate fraction of purple passion fruit peel against Staphylococcus aureus and Escherichia coli. Simplicia and ethyl acetate fraction were determinated  its phytochemical properties.  The extraction process by percolation method using ethanol  96% and continue to fractionation process by liquid liquid extraction method using n-hexane and ethyl acetate. The antibacterial activity were tested  against Staphylococcus aureus and Escherichia coli using agar diffusion method with paper discs. The result showed  that  the simplicia characteristic of passion fruit peel  were water content of  8.64%, water soluble extract of  31.69%, ethanol soluble extract of 13.02%, ash total of 7.89%, and insoluble ash in acid of 0.816%. The phytochemical screening simplicia and ethyl acetate fraction showed the presence of flavonoids, glycosides, saponins and tannins. The antibacterial activity test showed that the ethyl acetate fraction has an effective inhibition at the concentration of 100 mg/ml against Staphylococcus aureus and Escherichia coli, it showed dose dependent manner. The ethyl acetate fraction of passion fruit peel (Passiflora edulis Sims) has an antibacterial activity  on Staphylococcus aureus and Escherichia coli


2018 ◽  
Vol 1 (2) ◽  
pp. 29-34
Author(s):  
Sony Eka Nugraha ◽  
Suryadi Achmad ◽  
Erly Sitompul

Abstract.North Sumatera is the central production of  purple passion fruit  in Indonesia. Passion fruit was  processing into beverage product that produced passion fruit peel waste. The passion fruit peel has potential effect as a sources of medicine which is need to be examined such as its antibacterial effect. The purpose of this study was to determine the characterization of simplicia, phytochemical screening  and antibacterial activity of ethanol extract of purple passion fruit peel against Staphylococcus aureus and Escherichia coli. The simplicia powder was examined its characteristic include water content, water soluble extract, ethanol soluble extract, total ash and acid insoluble ash assay. The extraction was process by percolation method using ethanol  96% , then tested antibacterial activity against Staphylococcus aureus and Escherichia coli using agar diffusion method with paper discs.The result showed  that  the simplicia characteristic of passion fruit peel  were water content of  8.64%, water soluble extract of  31.69%, ethanol soluble extract of 13.02%, ash total of 7.89%, and insoluble ash in acid of 0.816%. The phytochemical screening simplicia and ethanol extract showed the presence of flavonoid, glycoside, saponin, tannin and steroid/triterpenoid.The antibacterial activity test showed that the ethanol extract has an effective inhibition at the  concentration of 300 mg/ml against Staphylococcus aureus and Escherichia coli, it showed dose dependent manner.   Keywords: Passiflora edulis Sims, antibacterial, passion fruit peel, Staphylococcus aureus and Escherichia coli        


2015 ◽  
Vol 4 (4) ◽  
pp. 32-38
Author(s):  
Hari Surya Purnama ◽  
Herbert ◽  
Rondang Tambun

The purpose of this study was to determine the optimum of combustion time and temperature of ash production from purple passion fruit peel (Parcilora idollis Sims f edulis Deg.). The experiment was begun to dry passion fruit peel, then combustion to obtaine the ash from passion fruit peel. The combustion was done by muffle furnace which time variables were from 1, 2, 3, 4, 5 hours and burning temperature variables were from 400 oC, 500 oC, 600 oC, 700 oC. The potassium that contained in ash have been extracted by distilled water with volume comparison was 1 : 10 for 24 hours. Observed responses were ash content, normality, pH, conductivity and potassium oxide content (% K2O). The best result of ash was in 5 hours with temperature 500 oC. The ash was analyzed by using AAS Atomic Absorption Spectroscopy, and 39,95 % of potassium oxide (K2O) content was obtained as maximum result.


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