Erbium: Yttrium-Aluminum-Garnet Laser Application in Stapedotomy

2005 ◽  
Vol 133 (6) ◽  
pp. 923-928 ◽  
Author(s):  
Jacopo Galli ◽  
Claudio Parrilla ◽  
Antonella Fiorita ◽  
Maria Raffaella Marchese ◽  
Gaetano Paludetti
Keyword(s):  
Inner Ear ◽  
Yttrium Aluminum Garnet ◽  
Er:Yag Laser ◽  
Bone Conduction ◽  
Stapes Surgery ◽  
Clinical Safety ◽  
Erbium Laser ◽  
Significant Difference ◽  
Yttrium Aluminum ◽  
Student’S T

OBJECTIVE: To assess clinical safety and efficacy of the erbium: yttrium-aluminum-garnet (Er:YAG) laser in the stapes surgery; to define and optimize parameters that render the procedure safe for the inner ear. STUDY DESIGN: Retrospective study. MATERIAL AND METHODS: A microscope-integrated Er: YAG laser stapedotomy was performed on 29 patients and a conventional stapedotomy on 41 patients. An early (within 1 to 3 days after stapes surgery) and late (at least 6 weeks) pure-tone bone-conduction threshold audiogram was obtained. RESULTS: No statistically significant differences were found by Student's t test over all measured frequencies between pre- and postoperative bone-conduction thresholds in each group. There was no statistically significant difference for all frequencies between early (3 days) and late postoperative mean bone-conduction thresholds. CONCLUSIONS: The results of our preliminary clinical study showed that erbium laser poses no risk to inner ear function. However, the lack of standardization obliges further investigation to establish safe clinical parameters of the Er:YAG laser. EBM RATING: B-3

scholarly journals Using erbium-doped yttrium aluminum garnet laser irradiation in different energy output levels versus ultrasonic in removal of root canal filling materials in endodontic retreatment

2017 ◽  
Vol 11 (03) ◽  
pp. 281-286 ◽  
Author(s):  
Mehmet Omer Gorduysus ◽  
Hanin Al-Rubai ◽  
Basheer Salman ◽  
Deena Al Saady ◽  
Hiba Al-Dagistani ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Root Canal ◽  
Yttrium Aluminum Garnet ◽  
Er:Yag Laser ◽  
Gutta Percha ◽  
Group I ◽  
Significant Difference ◽  
Erbium Doped ◽  
Yttrium Aluminum ◽  
Endodontic Retreatment

ABSTRACT Objectives: The objective of this study was to evaluate the efficacy of erbium-doped yttrium aluminum garnet (Er:YAG) laser irradiation in different energy outputs versus ultrasonic in gutta-percha removal during the endodontic retreatment. Materials and Methods: A total of 21 extracted human lower premolars were divided into three groups (n = 7). Following the standardized preparation of the root canals with Wave One Rotary system and obturation with gutta-percha: Group I was treated with ultrasonic, Group II by Er:YAG laser with 40 mJ/Pulse, and Group III by Er:YAG laser with 50 mJ/Pulse for the removal of gutta-percha from the canals. Two extra teeth were treated by Er:YAG laser with 135 mJ/Pulse as control group. For all groups, time for gutta-percha removal was recorded. Samples were then splited into two halves and tested by scanning electron microscope and stereomicroscopic evaluation under different magnification power to observe the efficacy of each method used in the removal of gutta-percha. Results: Statistical analysis of Kruskal–Wallis suggested that there are significant difference between the groups in relation to removal time (P < 0.05) and 2 × 2 Mann–Whitney U-test among the groups revealed that there is no significant difference between 40 and 50 mJ laser outputs (P > 0.05), but ultrasonic versus 40 and/or 50 mJ laser outputs were significantly different (P < 0.05). Conclusions: Er:YAG laser beam was not so efficient when compared to ultrasonic to reach the deeper parts of the canals as it was asserted, thermal side effects and burning damages were observed on the root canal dentinal walls. Moreover, the delivery system was not flexible enough to compensate the curvature of the canal system even though we used more straight canals as the sample ones as well as more time-consuming than the ultrasonic and more clinical time, rendering it to be less efficient in the removal of the obturation material during endodontic retreatment procedures.

Electrospun regenerated silk fibroin is a promising biomaterial for the maintenance of inner ear progenitors in vitro

2021 ◽  
pp. 088532822110515
Author(s):  
Guangfei Li ◽  
Yanbo Yin ◽  
Yaopeng Zhang ◽  
Jingfang Wu ◽  
Shan Sun
Keyword(s):  
Inner Ear ◽  
Silk Fibroin ◽  
Hair Cells ◽  
Engineering Research ◽  
Cell Mortality ◽  
Regenerated Silk Fibroin ◽  
Significant Difference ◽  
Student’S T ◽  
New Strategies

Objective We sought to determine the biocompatibility of electrospun regenerated silk fibroin (RSF) mats with inner ear progenitors, especially their effect on the differentiation of inner ear progenitors into hair cells. Methods Neonatal mouse cochleae (n = 20) were collected and digested and allowed to form spheres over several days. Cells digested from the spheres were then seeded onto aligned or random RSF mats, with laminin-coated coverslips serving as controls. The inner ear progenitor cell mortality was examined by TUNEL labeling, and the adhesion of cells to the RSF mats or coverslip was determined by scanning electron microscopy. Finally, the number of hair cells that differentiated from inner ear progenitors was determined by Myosin7a expression. Unpaired Student’s t-tests and one-way ANOVA followed by a Dunnett’s multiple comparisons test were used in this study ( p < 0.05). Results After 5 days of culture, the inner ear progenitors had good adhesion to both the aligned and random RSF mats and there was no significant difference in TUNEL+ cells between the mats compared to the coverslip ( p > 0.05). After 7 days of in vitro differentiation culture, the percentage of differentiated hair cells on the control, aligned, and random RSF mats was 2.5 ± 0.5%, 2.7 ± 0.4%, and 2.4 ± 0.2%, respectively, and there was no significant difference between Myosin7a+ cells on either RSF mat compared to controls ( p > 0.05). Conclusion The aligned and random RSF mats had excellent biocompatibility with inner ear progenitors and helped the inner ear progenitors maintain their stemness. Our results thus indicate that RSF mats represent a useful scaffold for the development of new strategies for inner ear tissue engineering research.

scholarly journals The effect of Erbium-doped Yttrium Aluminum Garnet laser irradiation on push-out bond strength of endodontic sealers with root canal dentin: An in vitro evaluation of push-out bond strength and failure modes

2021 ◽  
Vol 1 ◽  
pp. 2-8
Author(s):  
J. Sandeep Reddy ◽  
K. B. Jayalakshmi ◽  
I. Sujatha ◽  
Prasannalatha Nadig ◽  
Nilima Salim Isani ◽  
...  
Keyword(s):  
Bond Strength ◽  
Laser Irradiation ◽  
Root Canal ◽  
Yttrium Aluminum Garnet ◽  
Er:Yag Laser ◽  
Group I ◽  
Erbium Doped ◽  
Yttrium Aluminum ◽  
Ah Plus ◽  
Push Out

Objectives: The aim of this study was to evaluate and compare the push-out bond strength of bioceramic sealer and resin-based sealer on Erbium-doped Yttrium Aluminum Garnet (Er:YAG) treated root canals. Material and Methods: Sixty single-rooted teeth were collected, decoronated apical to the cementoenamel junction, maintaining the minimum root length of 14 mm. Samples were instrumented with WaveOne Gold primary file and divided into two experimental groups (n = 30), based on laser irradiation: Group I: No laser and Group II: Er:YAG laser irradiated. Groups I and II were again divided into two subgroups “a” (AH Plus) and “b” (mineral trioxide aggregate [MTA] Fillapex) with 15 samples in each group. As per the grouping, sealers were coated onto the canal walls and obturated. After 24 h of storage in 100% humidity at 37°C, all the samples were sectioned transversely and push-out test was performed using universal testing machine. Stereomicroscope was used to determine the mode of failure. A one-way analysis of variance was employed to compare the mean POBS. Kolmogorov–Smirnov and Shapiro–Wilk parametric tests were done to check the normality. The Games-Howell multiple post hoc test was used for pairwise comparison of the groups at a 95% confidence level. Results: Both AH Plus and MTA Fillapex exhibited higher bond strength in the laser-treated canals. AH plus exhibited superior bond strength compared to MTA Fillapex in both laser and non-laser-treated groups (P < 0.05). AH Plus groups have predominantly presented cohesive failure whereas MTA Fillapex presented mixed failures. Conclusion: Irradiation with Er:YAG laser in the root canal before obturation improves the bond strength significantly. The adhesive properties of MTA Fillapex are comparable to that of AH Plus.

scholarly journals Analysis of visual outcome of Neodymium: Yttrium-Aluminum -Garnet (Nd: YAG) laser capsulotomy in patients with Posterior Capsule Opacification

2020 ◽  
Vol 5 (8) ◽  
pp. 216-223
Author(s):  
Dr. Deepa R. ◽  
◽  
Dr. V. Panimalar A. Veeramani ◽  
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Yttrium Aluminum Garnet ◽  
Visual Outcome ◽  
Posterior Capsular Opacification ◽  
P Value ◽  
Yag Laser ◽  
Significant Difference ◽  
Yttrium Aluminum ◽  
Neodymium Yttrium

Objective: Posterior capsular opacification (PCO) is a postoperative complication causing decreasedvisual acuity. This study aims to study the efficacy of Nd: YAG laser capsulotomy in posteriorcapsular opacification following cataract surgery by analyzing the visual outcome. Material andMethods: A prospective study included a sample size of 50 eyes of 37 patients with Posteriorcapsular opacification following uneventful cataract surgery with significantly decreased visual acuity.Detailed anterior and posterior segment examination was done, best-corrected visual acuity (BCVA)was recorded along with measurement of IOP. Posterior capsulotomy was performed using Nd: YAGlaser (Neodymium: Yttrium-aluminum–garnet) and patients were followed up. Visual acuity wasassessed and complications if any were recorded. Results: It was noted that 74% of the patients atthe end of 1st week and 78% of the patients at the end of 1st and 3rd month had significant visualimprovement following Nd: YAG laser capsulotomy. There was a statistically significant difference inPost Nd: YAG laser BCVA on follow up with P-value <0.001. Complications encountered were the risein IOP in 6% of the population at the end of 1 hour and 1st day of the procedure, iris bleeding wasnoted in 4% of the population, intraocular lens damage in 2 %, and cystoid macular edema in 2 %of the study population.

scholarly journals Acid Resistance of Erbium-doped Yttrium Aluminum Garnet Laser–Treated and Phosphoric Acid–Etched Enamels

2006 ◽  
Vol 76 (6) ◽  
pp. 1052-1056 ◽  
Author(s):  
Jung-Ho Kim ◽  
Oh-Won Kwon ◽  
Hyung-Il Kim ◽  
Yong Hoon Kwon
Keyword(s):  
Laser Ablation ◽  
Phosphoric Acid ◽  
Yttrium Aluminum Garnet ◽  
Er:Yag Laser ◽  
Reduction Rate ◽  
Acid Resistance ◽  
Mineral Dissolution ◽  
Acid Etching ◽  
Erbium Doped ◽  
Yttrium Aluminum

Abstract Objective: To compare the effects of erbium-doped yttrium aluminum garnet (Er:YAG) laser ablation and of phosphoric acid etching on the in vitro acid resistance of bovine enamel. Materials and Methods: Teeth were polished to make the surface flat. The polished enamel was either etched with 37% phosphoric acid for 30 seconds or ablated with a single 33 J/cm2 pulse from an Er:YAG laser. The control specimens were free from acid etching and laser ablation. Changes in crystal structure, dissolved mineral (calcium [Ca] and phosphorus [P]) contents, and calcium distribution in the enamel subsurface after a pH-cycling process were evaluated. Results: After laser treatment, poor crystal structures improved without forming any new phases, such as tricalcium phosphates. Among the tested enamels, dissolved mineral contents were significantly different (P &lt; .05). Er:YAG laser–treated enamels had the lowest mineral dissolution (Ca, 13.78 ppm; P, 6.33 ppm), whereas phosphoric acid–etched enamels had the highest (Ca, 15.90 ppm; P, 7.33 ppm). The reduction rate and reduced depth of calcium content along the subsurface were lowest in Er:YAG laser–treated enamels. Conclusion: The Er:YAG laser–treated enamels are more acid resistant to acid attack than phosphoric acid–etched enamels.

Treatment of Scars with Er:YAG Laser in Patients with Cleft Lip: A Preliminary Report

2003 ◽  
Vol 40 (5) ◽  
pp. 518-522 ◽  
Author(s):  
Pier Francesco Nocini ◽  
Antonio D'Agostino ◽  
Lorenzo Trevisiol ◽  
Dario Bertossi
Keyword(s):  
Preliminary Report ◽  
Cleft Lip ◽  
Yttrium Aluminum Garnet ◽  
Er:Yag Laser ◽  
Treatment Approach ◽  
Dual Mode ◽  
Clinical Appearance ◽  
Primary Surgery ◽  
Bilateral Cleft Lip ◽  
Yttrium Aluminum

Objective Although one goal in cleft lip surgery is to avoid serious scarring, residual scars are often observed after primary surgery. The goal of this preliminary report was to present the standardized application of laser technology to reduce the appearance of residual scars. Design Ten patients with scarring after unilateral and bilateral cleft lip surgery were treated with a Dual Mode erbium yttrium-aluminum-garnet laser. This laser was recently introduced and had been used only for cosmetic applications, skin resurfacing, and correction of acne scars. Results An improvement in the clinical appearance of the laser-treated scars was observed after the first treatment, with continued improvement after the second laser session. The clinically observed improvements were corroborated by the patients’ reports concerning satisfaction with the result. Conclusions The combined mechanisms of ablation/coagulation and shrinking of the skin caused by the laser, in addition to observed patient satisfaction and low risk associated with the procedure, suggest that this treatment approach can be effective in the correction of residual scarring in patients with cleft lip.

scholarly journals Short-term results of the combined application of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser and erbium-doped yttrium aluminum garnet (Er:YAG) laser in the treatment of periodontal disease: a randomized controlled trial

2021 ◽  
Author(s):  
Markus Laky ◽  
Maximilian Müller ◽  
Brenda Laky ◽  
Muazzez Arslan ◽  
Christian Wehner ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Yttrium Aluminum Garnet ◽  
Er:Yag Laser ◽  
Periodontal Treatment ◽  
Control Group ◽  
Treatment Results ◽  
Randomized Controlled ◽  
Combined Application ◽  
Yttrium Aluminum ◽  
Laser Group

Abstract Objectives Nd:YAG and Er:YAG lasers have been previously used as an adjunct in periodontal therapy. The aim of this single-blinded randomized controlled clinical trial was to evaluate the efficacy of a combined application of Nd:YAG and Er:YAG laser irradiation in periodontal treatment. Materials and methods Twenty-two patients with at least one site of ≥ 6 mm periodontal probing depth (PPD) after mechanical debridement with curettes and sonic instruments at periodontal reevaluation were included in the study. Patients were randomly allocated at a 1:1 ratio to either a combined Nd:YAG/Er:YAG laser therapy (test group) or a “turned off” laser therapy (control group). The Nd:YAG laser was used for periodontal pocket deepithelialization and to stabilize the resulting blood clot. The Er:YAG laser was primarily used for root surface modification. PPD (mm), clinical attachment level (CAL, mm), and bleeding on probing (BOP, +/−) at the site of laser treatment were evaluated at baseline and 2 months after treatment. Results The mean improvements from baseline to 2-month follow-up for PPD were significantly better in the laser group (2.05 ± 0.82 mm) compared to the control group (0.64 ± 0.90 mm; p = 0.001). Likewise, the gain in CAL was significantly better in the laser group (1.50 ± 1.10 mm) than in the control group (0.55 ± 1.01mm; p = 0.046). Conclusions The combined application of Nd:YAG and Er:YAG laser irradiation as an adjunct to conventional non-surgical therapy showed a significant beneficial effect on periodontal treatment results. Clinical relevance Combined Nd:YAG and Er:YAG laser irradiation could be a useful procedure additionally to conventional non-surgical periodontal therapy to improve periodontal treatment results. Clinical trial registration ISRCTN registry #ISRCTN32132076

scholarly journals Is preoperative bone conduction shape a prognostic factor in otosclerosis surgery?

2021 ◽  
Author(s):  
Rémi HERVOCHON ◽  
ALIX VAUTERIN ◽  
Ghizlene Lahlou ◽  
Yann Nguyen ◽  
Georges Lamas ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Bone Conduction ◽  
Stapes Surgery ◽  
Significant Difference ◽  
Impaired Group ◽  
Group 2 ◽  
Average Bone ◽  
Air Conduction ◽  
Better Than ◽  
Group 1

1. We focused on 175 patients operated on for otosclerosis. There were 89 in group 1 (preoperative 4000 Hz BC threshold better than 2000 Hz) and 86 in group 2 (preoperative 2000 Hz BC threshold better than 4000 Hz). 2. Preoperatively, there was no significant difference in terms of average bone conduction (BC) thresholds, average air conduction (AC) thresholds and air-bone gap (ABG) between the two groups. 3. Three months and 1 year after surgery, group 1 had better audiometric outcomes than group 2 in terms of average AC and BC thresholds and ABG. 4. Postoperative BC gain was better in group 1 than group 2, particularly at 500 Hz, 1000 Hz and 2000 Hz. 5. When the 4000 Hz BC threshold was preoperatively impaired (group 2), it was not worsened after stapes surgery. This was not the case in group 1.

Bone Cement Fixation of Stapedotomy Prostheses: Long-term Outcomes in Primary and Revision Stapes Surgery

2020 ◽  
pp. 000348942097133
Author(s):  
Pedrom C. Sioshansi ◽  
Amy Schettino ◽  
Seilesh C. Babu ◽  
Dennis I. Bojrab ◽  
Eric W. Sargent ◽  
...  
Keyword(s):  
Word Recognition ◽  
Bone Cement ◽  
Bone Conduction ◽  
Stapes Surgery ◽  
Long Term Outcomes ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
Revision Stapes Surgery

Objectives: To describe audiologic outcomes following hydroxyapatite bone cement fixation of stapedotomy prostheses. Methods: A retrospective case review at a tertiary neurotology referral center was performed of patients undergoing primary or revision stapedotomy between 2010 and 2017. Patients with hydroxyapatite bone cement fixation of stapes prostheses were assessed. Pre- and postoperative hearing was compared, consisting of air conduction (AC) and bone conduction (BC) pure-tone averages (PTA), air-bone gap (ABG), and word recognition scores (WRS). Short and long-term outcomes were assessed. Results: Forty-six patients with otosclerosis underwent stapedotomy with bone cement fixation: 21 primary cases and 25 revision cases, with an average follow-up time of 17 months. Mean AC PTA was 56 dB preoperatively, and 34 dB postoperatively ( P < .0001), while the ABG improved on average from 27 dB to 9 dB ( P < .0001). There was no significant difference in postoperative ABG between primary and revision stapes surgery (6 dB vs 10 dB, P = .07). These results persisted through long-term follow-up in a subgroup of patients with significantly longer follow-up time (mean 44 months). There was no significant change in BC PTA or word recognition scores. Three patients underwent subsequent revisions, one patient developed sensorineural hearing loss. Conclusion: Stapedotomy with bone cement fixation of the prosthesis provides excellent hearing outcomes in both primary and revision treatment of otosclerosis. Results are consistent and stable through long-term follow-up. The use of bone cement should be incorporated into the surgical armamentarium of the otologist for the prevention and treatment of loose-wire syndrome and incus necrosis.

scholarly journals Association Between Postoperative Vertigo and Hearing Outcomes After Stapes Surgery for Otosclerosis

2021 ◽  
pp. 014556132110230
Author(s):  
Katarzyna Job ◽  
Agnieszka Wiatr ◽  
Maciej Wiatr
Keyword(s):  
Inner Ear ◽  
Bone Conduction ◽  
Surgical Techniques ◽  
Negative Influence ◽  
Statistical Correlation ◽  
Stapes Surgery ◽  
Hearing Improvement ◽  
Bony Labyrinth ◽  
Postoperative Vertigo ◽  
Hearing Outcomes

Objective: During the postoperative period, most patients with otosclerosis report vertigo and/or nausea caused by interventions within the inner ear. The aim of this study was to evaluate both early and late vertigo associated with hearing improvement after stapes surgery for otosclerosis. Methods: The analysis included 170 patients admitted to the hospital undergoing their first surgery for otosclerosis. Audiological diagnostics, surgical techniques, and symptoms reported by the patients were all analyzed. Results: A statistical correlation and an unfavorable influence of late, undesired symptoms, such as vertigo, nausea/vomiting, and nystagmus, on final hearing improvement after surgical treatment of otosclerosis were found. Prostheses that were too long or placed too deep within the inner ear space were the most frequent cause of both vertigo and lack of hearing improvement observed after stapedotomy. Conclusions: A significant negative influence on bone conduction thresholds, particularly at 2000 Hz, was associated with vestibular symptoms persisting for 7 days after the surgery. Symptoms of impaired bony labyrinth function after stapedotomy, persisting for more than 1 year, were associated with insufficient reduction of the air–bone gap and worse improvement in bone conduction thresholds at 1000 and 2000 Hz. The cause of both problems was related to a prosthesis that was too long or placed too deep in the inner ear during stapedotomy.

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