The relationship between angiotensin-converting enzyme (ACE) genotype, serum ACE concentration and markers of asymmetrical growth restriction in premature infants

2007 ◽  
Vol 17 (10) ◽  
pp. 417-418
Author(s):  
S. Redpath ◽  
L. Mills ◽  
D. McLean ◽  
V. Godfrey ◽  
M. Wallace ◽  
...  
2005 ◽  
Vol 33 (03) ◽  
pp. 501-505 ◽  
Author(s):  
Jae-Young Um ◽  
Nyeon-Hyoung An ◽  
Gui-Bi Yang ◽  
Geon-Mok Lee ◽  
Ju-Jang Cho ◽  
...  

Iridology is the study of the iris of the eye to detect the conditions of the body and its organs, genetic strengths and weaknesses, etc. Although iridology is not widely used as a scientific tool for healthcare professionals to get to the source of people's health conditions, it has been used as a supplementary source to help the diagnosis of medical conditions by noting irregularities of the pigmentation in the iris among some Korean Oriental medical doctors. Angiotensin converting enzyme (ACE) gene polymorphism is one of the most well studied genetic markers of vascular disease. We investigated the relationship between iridological constitution and ACE polymorphism in hypertensives. We classified 87 hypertensives and 79 controls according to iris constitution and determined the ACE genotype of each individual. DD genotype was more prevalent in patients with a neurogenic constitution than in controls. This finding supports the hypothesis that D allele is a candidate gene for hypertension and demonstrates the association among ACE genotype, Korean hypertensives and iris constitution.


1999 ◽  
Vol 87 (3) ◽  
pp. 1035-1037 ◽  
Author(s):  
Roger R. Taylor ◽  
Cyril D. S. Mamotte ◽  
Kieran Fallon ◽  
Frank M. van Bockxmeer

The deletion (D) allele of the gene for angiotensin-converting enzyme (ACE) is associated with higher plasma and tissue levels of the enzyme and has also been related to a variety of cardiovascular complications, particularly myocardial infarction. On the basis of indirect evidence, we hypothesized that inheritance of the D allele would contribute to elite athletic ability. Over a period of 4 yr, 120 Caucasian athletes who were national (Australian) representatives in sports demanding a high level of aerobic fitness were recruited. Their ACE genotypes were compared with those of a community control group recruited randomly from the electoral roll. There was no difference in ACE genotype frequencies between the two groups. The DD genotype frequency was 30% in athletes and 29% in the control group, and the II genotype frequency was 22.5 and 22%, respectively. The results do not exclude the possibility that ACE genotype could be related to some attribute relating to a specific type of elite athletic ability or that there may be a difference between genders. Larger studies are desirable.


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