scholarly journals Automatic evaluation of contours in radiotherapy planning utilising conformity indices and machine learning

2020 ◽  
Vol 16 ◽  
pp. 149-155
Author(s):  
Samsara Terparia ◽  
Romaana Mir ◽  
Yat Tsang ◽  
Catharine H Clark ◽  
Rushil Patel
2021 ◽  
Vol 52 (2) ◽  
pp. S3
Author(s):  
Grace Tsui ◽  
Derek S. Tsang ◽  
Chris McIntosh ◽  
Thomas G. Purdie ◽  
Glenn Bauman ◽  
...  

2019 ◽  
Vol 29 (2) ◽  
pp. 393-405 ◽  
Author(s):  
Magdalena Piotrowska ◽  
Gražina Korvel ◽  
Bożena Kostek ◽  
Tomasz Ciszewski ◽  
Andrzej Cżyzewski

Abstract Automatic classification methods, such as artificial neural networks (ANNs), the k-nearest neighbor (kNN) and self-organizing maps (SOMs), are applied to allophone analysis based on recorded speech. A list of 650 words was created for that purpose, containing positionally and/or contextually conditioned allophones. For each word, a group of 16 native and non-native speakers were audio-video recorded, from which seven native speakers’ and phonology experts’ speech was selected for analyses. For the purpose of the present study, a sub-list of 103 words containing the English alveolar lateral phoneme /l/ was compiled. The list includes ‘dark’ (velarized) allophonic realizations (which occur before a consonant or at the end of the word before silence) and 52 ‘clear’ allophonic realizations (which occur before a vowel), as well as voicing variants. The recorded signals were segmented into allophones and parametrized using a set of descriptors, originating from the MPEG 7 standard, plus dedicated time-based parameters as well as modified MFCC features proposed by the authors. Classification methods such as ANNs, the kNN and the SOM were employed to automatically detect the two types of allophones. Various sets of features were tested to achieve the best performance of the automatic methods. In the final experiment, a selected set of features was used for automatic evaluation of the pronunciation of dark /l/ by non-native speakers.


2020 ◽  
Vol 196 (10) ◽  
pp. 856-867 ◽  
Author(s):  
Martin Kocher ◽  
Maximilian I. Ruge ◽  
Norbert Galldiks ◽  
Philipp Lohmann

Abstract Background Magnetic resonance imaging (MRI) and amino acid positron-emission tomography (PET) of the brain contain a vast amount of structural and functional information that can be analyzed by machine learning algorithms and radiomics for the use of radiotherapy in patients with malignant brain tumors. Methods This study is based on comprehensive literature research on machine learning and radiomics analyses in neuroimaging and their potential application for radiotherapy in patients with malignant glioma or brain metastases. Results Feature-based radiomics and deep learning-based machine learning methods can be used to improve brain tumor diagnostics and automate various steps of radiotherapy planning. In glioma patients, important applications are the determination of WHO grade and molecular markers for integrated diagnosis in patients not eligible for biopsy or resection, automatic image segmentation for target volume planning, prediction of the location of tumor recurrence, and differentiation of pseudoprogression from actual tumor progression. In patients with brain metastases, radiomics is applied for additional detection of smaller brain metastases, accurate segmentation of multiple larger metastases, prediction of local response after radiosurgery, and differentiation of radiation injury from local brain metastasis relapse. Importantly, high diagnostic accuracies of 80–90% can be achieved by most approaches, despite a large variety in terms of applied imaging techniques and computational methods. Conclusion Clinical application of automated image analyses based on radiomics and artificial intelligence has a great potential for improving radiotherapy in patients with malignant brain tumors. However, a common problem associated with these techniques is the large variability and the lack of standardization of the methods applied.


2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Xue Bai ◽  
Guoping Shan ◽  
Ming Chen ◽  
Binbing Wang

Abstract Background Intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) are standard physical technologies of stereotactic body radiotherapy (SBRT) that are used for patients with non-small-cell lung cancer (NSCLC). The treatment plan quality depends on the experience of the planner and is limited by planning time. An automated planning process can save time and ensure a high-quality plan. This study aimed to introduce and demonstrate an automated planning procedure for SBRT for patients with NSCLC based on machine-learning algorithms. The automated planning was conducted in two steps: (1) determining patient-specific optimized beam orientations; (2) calculating the organs at risk (OAR) dose achievable for a given patient and setting these dosimetric parameters as optimization objectives. A model was developed using data of historical expertise plans based on support vector regression. The study cohort comprised patients with NSCLC who were treated using SBRT. A training cohort (N = 125) was used to calculate the beam orientations and dosimetric parameters for the lung as functions of the geometrical feature of each case. These plan–geometry relationships were used in a validation cohort (N = 30) to automatically establish the SBRT plan. The automatically generated plans were compared with clinical plans established by an experienced planner. Results All 30 automated plans (100%) fulfilled the dose criteria for OARs and planning target volume (PTV) coverage, and were deemed acceptable according to evaluation by experienced radiation oncologists. An automated plan increased the mean maximum dose for ribs (31.6 ± 19.9 Gy vs. 36.6 ± 18.1 Gy, P < 0.05). The minimum, maximum, and mean dose; homogeneity index; conformation index to PTV; doses to other organs; and the total monitor units showed no significant differences between manual plans established by experts and automated plans (P > 0.05). The hands-on planning time was reduced from 40–60 min to 10–15 min. Conclusion An automated planning method using machine learning was proposed for NSCLC SBRT. Validation results showed that the proposed method decreased planning time without compromising plan quality. Plans generated by this method were acceptable for clinical use.


Author(s):  
S. Yashaswini ◽  
S. S. Shylaja

Performance metrics give us an indication of which model is better for which task. Researchers attempt to apply machine learning and deep learning models to measure the performance of models through cost function or evaluation criteria like Mean square error (MSE) for regression, accuracy, and f1-score for classification tasks Whereas in NLP performance measurement is a complex due variation of ground truth and results obta.


2020 ◽  
Vol 150 ◽  
pp. S15
Author(s):  
Grace Tsui ◽  
Derek Tsang ◽  
Chris McIntosh ◽  
Tom Purdie ◽  
Mohammad Khandwala ◽  
...  

2022 ◽  
Author(s):  
K. Harrison ◽  
H. Pullen ◽  
C. Welsh ◽  
O. Oktay ◽  
J. Alvarez-Valle ◽  
...  

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