Dioscin and methylprotodioscin isolated from the root of Asparagus cochinchinensis suppressed the gene expression and production of airway MUC5AC mucin induced by phorbol ester and growth factor

Hyun Jae Lee; Jin Sung Park; Yong Pill Yoon; Ye Jin Shin; Sang Kook Lee; Yeong Shik Kim; Jang-Hee Hong; Kun Ho Son; Choong Jae Lee

doi:10.1016/j.phymed.2015.03.009

Dioscin and methylprotodioscin isolated from the root of Asparagus cochinchinensis suppressed the gene expression and production of airway MUC5AC mucin induced by phorbol ester and growth factor

Phytomedicine ◽

10.1016/j.phymed.2015.03.009 ◽

2015 ◽

Vol 22 (5) ◽

pp. 568-572 ◽

Cited By ~ 12

Author(s):

Hyun Jae Lee ◽

Jin Sung Park ◽

Yong Pill Yoon ◽

Ye Jin Shin ◽

Sang Kook Lee ◽

...

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Phorbol Ester ◽

Asparagus Cochinchinensis

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Growth Factor- and Phorbol Ester-induced Production and Gene Expression of MUC5AC Mucin in Human Airway Epithelial NCI-H292 Cells Were Inhibited by Afzelin and Natural Products Derived from Houttuynia Cordata

Natural Product Sciences ◽

10.20307/nps.2019.25.3.248 ◽

2019 ◽

Vol 25 (3) ◽

pp. 248

Author(s):

Yu-jin Kim ◽

Hyun Jae Lee ◽

Choong Jae Lee

Keyword(s):

Gene Expression ◽

Natural Products ◽

Growth Factor ◽

Phorbol Ester ◽

Airway Epithelial ◽

Houttuynia Cordata ◽

Human Airway

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Effects of Several Drugs for Metabolic Syndrome on Phorbol Ester- or Epidermal Growth Factor-induced Gene Expression and Production of Airway MUC5AC Mucin: Investigation of Potential Regulator for Hypersecretion of Airway Mucus using Drug Repositioning Strategy

Yakhak Hoeji ◽

10.17480/psk.2021.65.6.424 ◽

2021 ◽

Vol 65 (6) ◽

pp. 424-431

Author(s):

Hyun Jae Lee ◽

Choong Jae Lee

Keyword(s):

Gene Expression ◽

Metabolic Syndrome ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phorbol Ester ◽

Drug Repositioning ◽

Epidermal Growth ◽

Airway Mucus

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Effects of Natural Products Derived from Persicae Semen including Daucosterol on gene Expression and Production of Respiratory Mucin induced by Growth Factor and Phorbol Ester

Yakhak Hoeji ◽

10.17480/psk.2018.62.4.284 ◽

2018 ◽

Vol 62 (4) ◽

pp. 284-291

Author(s):

Hyun Jae Lee ◽

Keyword(s):

Gene Expression ◽

Natural Products ◽

Growth Factor ◽

Phorbol Ester ◽

Respiratory Mucin ◽

Persicae Semen

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Human fibroblast growth factor 1 gene expression in vascular smooth muscle cells is modulated via an alternate promoter in response to serum and phorbol ester

Nucleic Acids Research ◽

10.1093/nar/23.3.434 ◽

1995 ◽

Vol 23 (3) ◽

pp. 434-441 ◽

Cited By ~ 24

Author(s):

Maqsood A. Chotani ◽

Robert A. Payson ◽

Jeffrey A. Winkles ◽

Ing-Ming Chiu

Keyword(s):

Gene Expression ◽

Smooth Muscle ◽

Growth Factor ◽

Smooth Muscle Cells ◽

Fibroblast Growth Factor ◽

Vascular Smooth Muscle Cells ◽

Phorbol Ester ◽

Human Fibroblast ◽

Fibroblast Growth ◽

Alternate Promoter

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Type beta 1 transforming growth factor gene expression. A corrected mRNA structure reveals a downstream phorbol ester responsive element in human cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)39962-4 ◽

1990 ◽

Vol 265 (4) ◽

pp. 2203-2208

Author(s):

L Scotto ◽

P I Vaduva ◽

R E Wager ◽

R K Assoian

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Phorbol Ester ◽

Transforming Growth Factor ◽

Human Cells ◽

Factor Gene ◽

Mrna Structure ◽

Growth Factor Gene ◽

Responsive Element

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Polypeptide hormone regulation of gene transcription: specific 5' genomic sequences are required for epidermal growth factor and phorbol ester regulation of prolactin gene expression.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.81.10.2975 ◽

1984 ◽

Vol 81 (10) ◽

pp. 2975-2979 ◽

Cited By ~ 31

Author(s):

S. C. Supowit ◽

E. Potter ◽

R. M. Evans ◽

M. G. Rosenfeld

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Gene Transcription ◽

Phorbol Ester ◽

Genomic Sequences ◽

Hormone Regulation ◽

Polypeptide Hormone ◽

Prolactin Gene ◽

Epidermal Growth

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Platelet-derived growth factor B-chain gene expression in mesangial cells: Effect of phorbol ester on gene transcription and mRNA stability

Molecular and Cellular Biochemistry ◽

10.1007/bf00928363 ◽

1994 ◽

Vol 140 (1) ◽

pp. 31-36 ◽

Cited By ~ 3

Author(s):

Basant Bhandari ◽

Kathleen Woodruff ◽

Hanna E. Abboud

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Gene Transcription ◽

Phorbol Ester ◽

Mrna Stability ◽

Mesangial Cells ◽

Platelet Derived Growth Factor ◽

Chain Gene ◽

Factor B

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Platelet derived growth factor-A chain gene expression in cultured mesangial cells: Regulation by phorbol ester at the level of mRNA abundance, transcription and mRNA stability

Molecular and Cellular Endocrinology ◽

10.1016/0303-7207(93)90271-k ◽

1993 ◽

Vol 91 (1-2) ◽

pp. 185-191 ◽

Cited By ~ 7

Author(s):

Basant Bhandari ◽

Hanna E. Abboud

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Phorbol Ester ◽

Mrna Stability ◽

Mesangial Cells ◽

Mrna Abundance ◽

Platelet Derived Growth Factor ◽

Chain Gene ◽

A Chain

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Inhibition of airway MUC5AC mucin production and gene expression induced by epidermal growth factor or phorbol ester by glycyrrhizin and carbenoxolone

Phytomedicine ◽

10.1016/j.phymed.2010.11.003 ◽

2011 ◽

Vol 18 (8-9) ◽

pp. 743-747 ◽

Cited By ~ 10

Author(s):

Hyun Jae Lee ◽

Su Yel Lee ◽

Heung Seog Bae ◽

Jang-Hyun Kim ◽

Gyu Tae Chang ◽

...

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phorbol Ester ◽

Mucin Production ◽

Epidermal Growth

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Epidermal growth factor and phorbol ester regulate prolactin gene expression via distinct pathways

Molecular and Cellular Endocrinology ◽

10.1016/0303-7207(90)90094-o ◽

1990 ◽

Vol 69 (1) ◽

pp. R7-R11 ◽

Cited By ~ 7

Author(s):

Arthur E. Jackson ◽

Sudip K. Bandyopadhyay ◽

Carter Bancroft

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phorbol Ester ◽

Prolactin Gene ◽

Epidermal Growth

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