Assess the level of functional impairment among patients with Parkinson's disease attending the institute of neurology national hospital Sri Lanka

Physiotherapy ◽  
2015 ◽  
Vol 101 ◽  
pp. e705-e706
Author(s):  
H.H.N. Kalyani ◽  
R. Sarangi Thanthrige
2019 ◽  
Vol 19 (7) ◽  
pp. 1022-1031 ◽  
Author(s):  
Paula D. Cebrián ◽  
Omar Cauli

Background: Many neurological disorders lead to institutionalization and can be accompanied in their advanced stages by functional impairment, and progressive loss of mobility, and cognitive alterations. Objective: We analyzed the relationship between functional impairment and cognitive performance and its related subdomains in individuals with Parkinson’s disease, Alzheimer’s disease accompanied by motor dysfunction, and with other neurological disorders characterized by both motor and cognitive problems. Methods: All participants lived in nursing homes (Valencia, Spain) and underwent cognitive evaluation with the Mini-Mental State Examination; functional assessment of independence in activities of daily living using the Barthel score and Katz index; and assessment of mobility with the elderly mobility scale. Results: The mean age of the subjects was 82.8 ± 0.6 years, 47% of the sample included individuals with Parkinson’s disease, and 48 % of the sample presented severe cognitive impairment. Direct significant relationships were found between the level of cognitive impairment and functional capacity (p < 0.01) and mobility (p < 0.05). Among the different domains, memory impairment was not associated with altered activities of daily living or mobility. The functional impairment and the risk of severe cognitive impairment were significantly (p<0.05) higher in female compared to male patients. Among comorbidities, overweight/obesity and diabetes were significantly (p < 0.05) associated with poor cognitive performance in those individuals with mild/moderate cognitive impairment. Conclusion: In institutionalized individuals with movement disorders there is an association between functional and cognitive impairment. Reduction of over-weight and proper control of diabetes may represent novel targets for improving cognitive function at such early stages.


10.3823/2516 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Ruwani Wijeyekoon ◽  
Vindika Suriyakumara ◽  
Ranjanie Gamage ◽  
Tharushi Fernando ◽  
Amila Jayasuriya ◽  
...  

Background- Information on lifestyle factors (eg. coffee /tea drinking, smoking) and Parkinson’s Disease(PD) in South Asia is limited. The objective of this study was to determine associations between lifestyle factors and PD in a clinic-based study in Sri Lanka. Methods–Demographic and lifestyle factor data was collected from an unselected cohort of PD patients and age and gender-matched controls attending clinics in Greater Colombo, Sri Lanka. Findings–Of 229 patients with parkinsonism, 144 had Idiopathic PD. Controls numbered 102. Coffee drinkers and smokers were significantly less likely to have PD (coffee, p<0.001; OR=0.264; smoking, p=0.043; OR=0.394). Coffee drinkers were older at PD onset(p<0.001). Similar trends seen with tea drinking were not statistically significant. Conclusions -This is the first formal study of PD and these lifestyle factors in South Asia. It demonstrates an association between coffee drinking, smoking and a decreased prevalence of PD, and coffee drinking and later age of PD onset.  This is in line with other studies done worldwide, suggesting biological associations with global relevance.


2009 ◽  
Vol 24 (8) ◽  
pp. 1229-1233 ◽  
Author(s):  
Laura Silveira-Moriyama ◽  
Dharshana Sirisena ◽  
Pasan Gamage ◽  
Ranjanie Gamage ◽  
Rohan de Silva ◽  
...  

2009 ◽  
Vol 24 (11) ◽  
pp. 1669-1675 ◽  
Author(s):  
David Weise ◽  
Reinhard Lorenz ◽  
Mira Schliesser ◽  
Andreas Schirbel ◽  
Karlheinz Reiners ◽  
...  

2016 ◽  
Vol 19 (6) ◽  
pp. 709-724 ◽  
Author(s):  
Chung-Han Hsieh ◽  
Atossa Shaltouki ◽  
Ashley E. Gonzalez ◽  
Alexandre Bettencourt da Cruz ◽  
Lena F. Burbulla ◽  
...  

2017 ◽  
Vol 75 (5) ◽  
pp. 314-316 ◽  
Author(s):  
Francisco Cardoso

ABSTRACT Andrew Lees, Professor of Neurology at the National Hospital Queen Square (London, UK), has been recognized as the world’s most highly-cited researcher over the 200-year history of Parkinson’s Disease. Although he remains actively involved in the investigation of movement disorders, Prof. Lees embarked on a literary career that started in 2011 with the publication of a social history of his native Liverpool. His last work is Mentored by a Madman: The William Burroughs Experiment, which is reviewed here.


2020 ◽  
Vol 91 (8) ◽  
pp. e1.2-e1
Author(s):  
AJ Lees

Born on Merseyside, Andrew Lees qualified in medicine at the Royal London Hospital Medical College in 1970. His neurological training was at University College London Hospitals and the National Hospital for Neurology and Neurosurgery, Queen Square. He also spent 1 year at L’Hopital Salpetriere, Paris. He has achieved international recognition for his work on Parkinson’s disease and abnormal movement disorders. He is an original member of the Highly-Cited Researchers ISI Database with an h-index of 130. Founder member of the international Movement Disorder Society, he was elected President (2004–2006) and co-edited the Movement Disorders Journal between 1995 and 2003. In 2006, he was awarded the Movement Disorders Research Award by the American Academy of Neurology and he was awarded the Association of British Neurologists Medal in 2015.At the age of thirty-two he was appointed to the consultant staff at the National Hospitals, The Middlesex, and Whittington Hospitals and in 1987 was elected a Fellow of the Royal College of Physicians. He was later appointed Professor of Neurology at the National Hospital for Neurology and Neurosurgery, Queen Square and was Director of the Reta Lila Weston Institute for Neurological Studies (1998–2012). He was Clinical Director of the Queen Square Brain Bank for Neurological Disorders (1985–2012) and Director of the Sara Koe PSP Research Centre (2002–2012).He is a Visiting Professor at the University of Liverpool and Queen Mary University of London, and has close collaborations with several Brazilian universities. For his contributions to Brazilian neurology he was elected as an overseas member of the Academia Nacional de Medicina and the Academia Brasileira de Neurologia. He was elected as a Council member of the Academy of Medical Sciences 2012–2015 and appointed as an Expert Adviser for the UK Government National Institute for Health and Care Excellence Centre for Guidelines (2006–2019). He received the Bing Spear Award in 2016 for outstanding contributions towards saner drug policies.He has delivered the Gowers Memorial Lecture at the National Hospital, The Inaugural Lord Brain Memorial Lecture at Bart’s and the Royal London Hospitals and David Marsden Memorial Lecture at the European Federation of Neurological Societies. He was the recipient of Stanley Fahn Lectureship Award at the MDS Dublin 2012, and has been awarded the German Society of Neurology’s 2012 Dingebauer Prize for outstanding scientific attainment in the field of Parkinson’s disease and Neurodegenerative Disorders, the Jay Van Andel award for outstanding research in Parkinson’s disease in 2014, and the Parkinson Canada’s Donald Calne Award and Lectureship for 2017.Through a process of reasoning that left little to the imagination the neurologists at The Royal London Hospital where I trained pulled black swans and zebras from their hats. During my training I was led to understand that it was just a matter of time before all disorders of the brain would be worked out and categorised in terms of anatomical electrical and chemical connections. This rational approach drew me in, and I selected diseases of the nervous system as my specialist subject.My first two neurology chiefs at University College Hospital were inspirational and kind. They warned me that it would take many years to learn how to join up the dots and become proficient at knowing where to look. One of them recommended that I should use textbooks only for reference but that I should read the Sherlock Holmes canon. Over time I came to understand that neurologists and criminal detectives both seek hidden truths and meanings in narrative and that both rely on a rigorous tried and tested method that pays attention to detail. Sherlock Holmes provided a romantic bridge to William Gowers and the serious business of neurology.Clinical research and a curiosity for cures should be an integral part of neurology William Seward Burroughs, who had appeared out of nowhere on the cover of Sergeant Pepper became my unlikely source of inspiration. He introduced me to the idea that nothing happens by chance and that novel scientific discoveries rely heavily on personally distinctive actions. He also helped me to understand that art is a complementary source of truth that enlists inventiveness to transport science beyond the acquisition of fact.


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