Prevalence of exercise intolerance and associated factors in asymptomatic adults underwent cardiopulmonary exercise testing: the role of body mass index

Physiotherapy ◽  
2015 ◽  
Vol 101 ◽  
pp. e326
Author(s):  
A. Matheus ◽  
A. Gagliardi ◽  
E. Sperandio ◽  
F. Almeida ◽  
V. Almeida ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Exercise Testing ◽  
Associated Factors ◽  
Cardiopulmonary Exercise Testing ◽  
Exercise Intolerance ◽  
Cardiopulmonary Exercise

Exercise Intolerance in Pulmonary Arterial Hypertension. The Role of Cardiopulmonary Exercise Testing

2015 ◽  
Vol 12 (4) ◽  
pp. 604-612 ◽  
Author(s):  
J. Alberto Neder ◽  
Roberta P. Ramos ◽  
Jaquelina S. Ota-Arakaki ◽  
Daniel M. Hirai ◽  
Christine L. D’Arsigny ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Exercise Intolerance ◽  
Cardiopulmonary Exercise ◽  
Pulmonary Arterial

scholarly journals The relationship between body mass index and cardiopulmonary exercise testing in chronic systolic heart failure

2009 ◽  
Vol 158 (4) ◽  
pp. S31-S36 ◽  
Author(s):  
Tamara B. Horwich ◽  
Eric S. Leifer ◽  
Clinton A. Brawner ◽  
Meredith B. Fitz-Gerald ◽  
Gregg C. Fonarow
Keyword(s):  
Heart Failure ◽  
Body Mass Index ◽  
Body Mass ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Systolic Heart Failure ◽  
Cardiopulmonary Exercise ◽  
Chronic Systolic Heart Failure ◽  
The Relationship

Allometric correction of peak VO2 in obese adults undergoing cardiopulmonary exercise testing

2019 ◽  
Vol 15 (2) ◽  
pp. 77-83
Author(s):  
A.C. Matheus ◽  
A.R.T. Gagliardi ◽  
E.F. Sperandio ◽  
M. Romiti ◽  
R.L. Arantes ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Normal Weight ◽  
Analysis Of Covariance ◽  
Obesity Class ◽  
Cardiopulmonary Exercise ◽  
Wide Range ◽  
Ratio Standards

We hypothesised that the reduction in cardiorespiratory fitness (CRF) of individuals with less severe obesity is small or non-existent when the allometric rather than the ratio standard is used for the comparison. We aimed to evaluate the influence of obesity on CRF, and to compare peak VO2 using allometric corrections in asymptomatic adults with a wide range of body mass index. The results of 780 adults (age 41±13 years) who underwent cardiopulmonary exercise testing (CPET) were evaluated. Participants were stratified according to body mass index (BMI): normal weight (n=227), overweight (n=198), and obese class 1 (n=155), 2 (n=131), and 3 (n=69). After cardiovascular risk assessment, the participants underwent CPET on a treadmill ramp protocol. The allometric exponents calculated were 0.60 and 0.62 for obese and non-obese groups respectively, with no significant differences. After using BMI strata in a multivariate analysis of covariance, we found an allometric exponent of 0.65. Peak VO2 using ratio standards significantly declined among all stratified groups. After allometric correction, peak VO2 remained significantly reduced only in women with obesity class 3 and men with obesity classes 2 and 3. When ratio standards were used to compare peak VO2, the effect of obesity on CRF was overestimated. Allometric correction of peak VO2 is more reasonable, and should be adopted as a routine for CPET.

scholarly journals Differences between treadmill and cycle ergometer cardiopulmonary exercise testing results in amateur triathletes and their association with body composition and body mass index

2021 ◽  
Author(s):  
Szymon Price ◽  
Szczepan Wiecha ◽  
Igor Cieśliński ◽  
Daniel Śliż ◽  
Przemysław Seweryn Kasiak ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Composition ◽  
Body Mass ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Bioelectrical Impedance ◽  
Cycle Ergometer ◽  
Fat Free Mass ◽  
Cardiopulmonary Exercise ◽  
Maximum Exertion

Abstract Cardiopulmonary exercise testing (CPET) is the method of choice to assess aerobic fitness. Previous research was ambiguous as to whether treadmill (Tr) and cycle ergometry (CE) results are transferrable or different between testing modalities in triathletes. The aim of this paper was to investigate the differences in HR and VO2 at maximum exertion and at anaerobic threshold (AT) and respiratory compensation point (RCP) and evaluate their association with body fat (BF), fat free mass (FFM), and body mass index (BMI). 143 adult (n = 18 female), amateur, Caucasian triathletes had both Tr, and CE CPET performed. The male group was divided into < 40 years (n = 80) and > 40years (n = 45). Body composition was measured with bioelectrical impedance before tests. Differences were evaluated using paired T-tests and associations were evaluated in males using multiple linear regression (MLR). Significant differences were found in VO2 and HR at maximum exertion, at AT and at RCP between CE and Tr testing, in both males and females. VO2AT was 38.8(± 4.6) ml/kg/min in Tr vs 32.8(± 5.4) in CE in males and 36.0(± 3.6) vs 32.1(± 3.8) in females (p < 0.001). HRAT was 149 (± 10) bpm in Tr vs 136 (± 11) in CE in males and 156 (± 7) vs 146 (± 11) in females (p < 0.001). VO2max was 52 (± 6) ml/kg/min vs 49 (± 7) in CE in males and 45.3 (± 4.9) in Tr vs 43.9 (± 5.2) in females (p < 0.001). HRmax was 183 (± 10) bpm in Tr vs 177 (± 10) in CE in males and 183 (± 9) vs 179 (± 10) in females (p < 0.001). MLR showed that BMI, BF and FFM are significantly associated with differences in HR and VO2 at maximum, AT and RCP in males aged > 40. Both tests should be used independently to achieve optimal fitness assessment and further training planning.

scholarly journals Cardiopulmonary exercise testing (CPET) in patients with end-stage kidney disease (ESKD): principles, methodology and clinical applications of the optimal tool for exercise tolerance evaluation

2021 ◽  
Author(s):  
Eva Pella ◽  
Afroditi Boutou ◽  
Aristi Boulmpou ◽  
Christodoulos E Papadopoulos ◽  
Aikaterini Papagianni ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Exercise Intolerance ◽  
End Stage Kidney Disease ◽  
Exercise Limitation ◽  
Cardiopulmonary Exercise ◽  
Functional Reserves ◽  
Increased Risk ◽  
End Stage

Abstract Chronic kidney disease (CKD), especially end-stage kidney disease (ESKD), is associated with increased risk for cardiovascular events and all-cause mortality. Exercise intolerance as well as reduced cardiovascular reserve are extremely common in patients with CKD. Cardiopulmonary exercise testing (CPET) is a non-invasive, dynamic technique that provides an integrative evaluation of cardiovascular, pulmonary, neuropsychological and metabolic function during maximal or submaximal exercise, allowing the evaluation of functional reserves of these systems. This assessment is based on the principle that system failure typically occurs when the system is under stress and, thus, CPET is currently considered to be the gold-standard for identifying exercise limitation and differentiating its causes. It has been widely used in several medical fields for risk stratification, clinical evaluation and other applications but its use in everyday practice for CKD patients is scarce. This article describes the basic principles and methodology of CPET and provides an overview of important studies that utilized CPET in patients with ESKD, in an effort to increase awareness of CPET capabilities among practicing nephrologists.

Risk stratification in hf with mid-range LVEF: the role of cardiopulmonary exercise testing

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
B.M.L Rocha ◽  
G.J Lopes Da Cunha ◽  
P.M.D Lopes ◽  
P.N Freitas ◽  
F Gama ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Exercise Testing ◽  
Primary Endpoint ◽  
Prognostic Significance ◽  
Cardiopulmonary Exercise Testing ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Cardiopulmonary Exercise

Abstract Background Cardiopulmonary exercise testing (CPET) is recommended in the evaluation of selected patients with Heart Failure (HF). Notwithstanding, its prognostic significance has mainly been ascertained in those with left ventricular ejection fraction (LVEF) &lt;40% (i.e., HFrEF). The main goal of our study was to assess the role of CPET in risk stratification of HF with mid-range (40–49%) LVEF (i.e., HFmrEF) compared to HFrEF. Methods We conducted a single-center retrospective study of consecutive patients with HF and LVEF &lt;50% who underwent CPET from 2003–2018. The primary composite endpoint of death, heart transplant or HF hospitalization was assessed. Results Overall, 404 HF patients (mean age 57±11 years, 78.2% male, 55.4% ischemic HF) were included, of whom 321 (79.5%) had HFrEF and 83 (20.5%) HFmrEF. Compared to the former, those with HFmrEF had a significantly higher mean peak oxygen uptake (pVO2) (20.2±6.1 vs 16.1±5.0 mL/kg/min; p&lt;0.001), lower median minute ventilation/carbon dioxide production (VE/VCO2) [35.0 (IQR: 29.1–41.2) vs 39.0 (IQR: 32.0–47.0); p=0.002) and fewer patients with exercise oscillatory ventilation (EOV) (22.0 vs 46.3%; p&lt;0.001). Over a median follow-up of 28.7 (IQR: 13.0–92.3) months, 117 (28.9%) patients died, 53 (13.1%) underwent heart transplantation, and 134 (33.2%) had at least one HF hospitalization. In both HFmrEF and HFrEF, pVO2 &lt;12 mL/kg/min, VE/VCO2 &gt;35 and EOV identified patients at higher risk for events (all p&lt;0.05). In Cox regression multivariate analysis, pVO2 was predictive of the primary endpoint in both HFmrEF and HFrEF (HR per +1 mL/kg/min: 0.81; CI: 0.72–0.92; p=0.001; and HR per +1 mL/kg/min: 0.92; CI: 0.87–0.97; p=0.004), as was EOV (HR: 4.79; CI: 1.41–16.39; p=0.012; and HR: 2.15; CI: 1.51–3.07; p&lt;0.001). VE/VCO2, on the other hand, was predictive of events in HFrEF but not in HFmrEF (HR per unit: 1.03; CI: 1.02–1.05; p&lt;0.001; and HR per unit: 0.99; CI: 0.95–1.03; p=0.512, respectively). ROC curve analysis demonstrated that a pVO2 &gt;16.7 and &gt;15.8 mL/kg/min more accurately identified patients at lower risk for the primary endpoint (NPV: 91.2 and 60.5% for HFmrEF and HFrEF, respectively; both p&lt;0.001). Conclusions CPET is a useful tool in HFmrEF. Both pVO2 and EOV independently predicted the primary endpoint in HFmrEF and HFrEF, contrasting with VE/VCO2, which remained predictive only in latter group. Our findings strengthen the prognostic role of CPET in HF with either reduced or mid-range LVEF. Funding Acknowledgement Type of funding source: None

scholarly journals Pulmonary Capillary Hemangiomatosis: The Role of Invasive Cardiopulmonary Exercise Testing

2015 ◽  
Vol 5 (3) ◽  
pp. 580-586 ◽  
Author(s):  
Hilary M. DuBrock ◽  
Richard L. Kradin ◽  
Josanna M. Rodriguez-Lopez ◽  
Richard N. Channick
Keyword(s):  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Cardiopulmonary Exercise ◽  
Pulmonary Capillary ◽  
Pulmonary Capillary Hemangiomatosis
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