scholarly journals Insight does not come at random: Individual gray matter networks relate to clinical and cognitive insight in schizophrenia

Author(s):  
Daouia I. Larabi ◽  
Jan-Bernard C. Marsman ◽  
André Aleman ◽  
Betty M. Tijms ◽  
Esther M. Opmeer ◽  
...  
Author(s):  
Steven M. Le Vine ◽  
David L. Wetzel

In situ FT-IR microspectroscopy has allowed spatially resolved interrogation of different parts of brain tissue. In previous work the spectrrscopic features of normal barin tissue were characterized. The white matter, gray matter and basal ganglia were mapped from appropriate peak area measurements from spectra obtained in a grid pattern. Bands prevalent in white matter were mostly associated with the lipid. These included 2927 and 1469 cm-1 due to CH2 as well as carbonyl at 1740 cm-1. Also 1235 and 1085 cm-1 due to phospholipid and galactocerebroside, respectively (Figs 1and2). Localized chemical changes in the white matter as a result of white matter diseases have been studied. This involved the documentation of localized chemical evidence of demyelination in shiverer mice in which the spectra of white matter lacked the marked contrast between it and gray matter exhibited in the white matter of normal mice (Fig. 3).The twitcher mouse, a model of Krabbe’s desease, was also studied. The purpose in this case was to look for a localized build-up of psychosine in the white matter caused by deficiencies in the enzyme responsible for its breakdown under normal conditions.


2013 ◽  
Vol 34 (3) ◽  
pp. 159-169 ◽  
Author(s):  
Sevtap Cinan ◽  
Aslı Doğan

This research is new in its attempt to take future time orientation, morningness orientation, and prospective memory as measures of mental prospection, and to examine a three-factor model that assumes working memory, mental prospection, and cognitive insight are independent but related higher-order cognitive constructs by using confirmatory factor analysis (CFA). The three-factor model produced a good fit to the data. An alternative one-factor model was tested and rejected. The results suggest that working memory and cognitive insight are distinguishable, related constructs, and that both are distinct from, but negatively associated with, mental prospection. In addition, structural equation modeling (SEM) showed that working memory had a strong positive effect on cognitive insight and a moderate negative effect on mental prospection.


1974 ◽  
Vol 19 (2) ◽  
pp. 102-103
Author(s):  
CARL GERBER
Keyword(s):  

2009 ◽  
Author(s):  
Vedat Sar ◽  
Erdinc Ozturk ◽  
Serkan Islam ◽  
Suat Kucukgoncu ◽  
Cigdem Yumbul

2011 ◽  
Vol 42 (01) ◽  
Author(s):  
S. Nägel ◽  
D. Holle ◽  
N. Desmarattes ◽  
N. Theysohn ◽  
C. Gaul ◽  
...  

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