The aim of this study was to evaluate the stress distribution of different retention systems (screwed, cemented, and mixed) in 5-unit implant-supported fixed partial dentures through the photoelasticity method. Twenty standardized titanium suprastructures were manufactured, of which 5 were screw retained, 5 were cement retained, and 10 were mixed (with an alternating sequence of abutments), each supported by 5 external hexagon (4.0 mm × 11.5 mm) implants. A circular polariscope was used, and an axial compressive load of 100 N was applied on a universal testing machine. The results were photographed and qualitatively analyzed. We observed the formation of isochromatic fringes as a result of the stresses generated around the implant after installation of the different suprastructures and after the application of a compressive axial load of 100 N. We conclude that a lack of passive adaptation was observed in all suprastructures with the formation of low-magnitude stress in some implants. When cemented and mixed suprastructures were subjected to a compressive load, they displayed lower levels of stress distribution and lower intensity fringes compared to the screwed prosthesis.