225. Delivery or expectant management for the prevention of adverse maternal and neonatal outcomes in hypertensive disorders of pregnancy: An individual patient data meta-analysis

2018 ◽  
Vol 13 ◽  
pp. S103-S104
Author(s):  
Thomas Patrick Bernardes ◽  
Eva Zwertbroek ◽  
Kim Broekhuijsen ◽  
Corine Koopmans ◽  
Kim Boers ◽  
...  
2015 ◽  
Vol 212 (5) ◽  
pp. 624.e1-624.e17 ◽  
Author(s):  
Miriam F. van Oostwaard ◽  
Josje Langenveld ◽  
Ewoud Schuit ◽  
Dimitri N.M. Papatsonis ◽  
Mark A. Brown ◽  
...  

2021 ◽  
Author(s):  
Marie Buitendyk ◽  
Wycliffe Kosgei ◽  
Julie Thorne ◽  
Heather Millar ◽  
Joy Marsha ◽  
...  

Abstract Background Preeclampsia is a major contributor to maternal and neonatal mortality worldwide. Ninety-nine percent of these deaths occur in resource limited settings. One of the greatest barriers to women seeking medical attention remains the cost of care. Kenya implemented a nation-wide policy change in 2013, offering free maternity services to all women to address this concern. Here, we explore the impact of this policy change on maternal and neonatal outcomes specific to the hypertensive disorders of pregnancy. Methods We conducted a retrospective cross-sectional chart review of women discharged or deceased with a diagnosis of gestational hypertension, preeclampsia, eclampsia or HELLP syndrome at a tertiary referral center in western Kenya one year before (June 1, 2012-May 31, 2013) and one year after (June 1, 2013-May 31, 2014) free maternity services were introduced at public facilities across the country. Demographic information, obstetric history, medical history, details of the current pregnancy, diagnosis on admission and at discharge, antepartum treatment, maternal outcomes, and neonatal outcomes were collected and compared. Results There were more in hospital deliveries after policy change was introduced. The proportion of women diagnosed with a hypertensive disorder of pregnancy was higher in the year before free maternity care although there was a statistically significant increase in the proportion of women diagnosed with gestational hypertension after policy change. Among those women diagnosed with hypertensive disorders, there was no difference in the proportion who developed obstetric or medical complications. Of concern, there was a statistically significant increase in the proportion of women dying as a result of their condition after policy change. There was a statistically significant increase in the use of magnesium sulfate for seizure prophylaxis. There was no overall difference in the use of anti-hypertensives between groups and no overall difference in the proportion of women who received dexamethasone for fetal lung maturity. Conclusions Free maternity services, however necessary, are insufficient to improve maternal and neonatal outcomes related to the hypertensive disorders of pregnancy at a tertiary referral center in western Kenya. Multiple complementary strategies acting in unison are urgently needed.


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