Herd demographics correlated with the spatial distribution of a foot-and-mouth disease epidemic in Buenos Aires province, Argentina

2004 ◽  
Vol 65 (3-4) ◽  
pp. 227-237 ◽  
Author(s):  
Michael P. Ward ◽  
Andres M. Perez
1976 ◽  
Vol 77 (1) ◽  
pp. 1-9 ◽  
Author(s):  
M. E. Hugh-Jones

SUMMARYA computer model was constructed to mimic the 1967–8 foot-and-mouth epizootic in Shropshire and Cheshire, but the daily spatial distribution of outbreaks was randomized. This pattern of outbreaks was then examined to determine what percentage of outbreaks would fulfil an arbitrary set of criteria for milk-lorry-borne disease, or the primary movement of milk. Some 21% of herds visited subsequent to a ‘source farm’ were affected, as were 4% of herds visited after any infected herd. The relevance of these results to the true risk of disease through the primary movement of milk off affected farms is discussed.


Author(s):  
Suyan Yi ◽  
Hongwei Wang ◽  
Shengtian Yang ◽  
Ling Xie ◽  
Yibo Gao ◽  
...  

Background: As the global climate changes, the number of cases of hand-foot-and-mouth disease (HFMD) is increasing year by year. This study comprehensively considers the association of time and space by analyzing the temporal and spatial distribution changes of HFMD in the Ili River Valley in terms of what climate factors could affect HFMD and in what way. Methods: HFMD cases were obtained from the National Public Health Science Data Center from 2013 to 2018. Monthly climate data, including average temperature (MAT), average relative humidity (MARH), average wind speed (MAWS), cumulative precipitation (MCP), and average air pressure (MAAP), were obtained from the National Meteorological Information Center. The temporal and spatial distribution characteristics of HFMD from 2013 to 2018 were obtained using kernel density estimation (KDE) and spatiotemporal scan statistics. A regression model of the incidence of HFMD and climate factors was established based on a geographically and temporally weighted regression (GTWR) model and a generalized additive model (GAM). Results: The KDE results show that the highest density was from north to south of the central region, gradually spreading to the whole region throughout the study period. Spatiotemporal cluster analysis revealed that clusters were distributed along the Ili and Gongnaisi river basins. The fitted curves of MAT and MARH were an inverted V-shape from February to August, and the fitted curves of MAAP and MAWS showed a U-shaped change and negative correlation from February to May. Among the individual climate factors, MCP coefficient values varied the most while MAWS values varied less from place to place. There was a partial similarity in the spatial distribution of coefficients for MARH and MAT, as evidenced by a significant degree of fit performance in the whole region. MCP showed a significant positive correlation in the range of 15–35 mm, and MAAP showed a positive correlation in the range of 925–945 hPa. HFMD incidence increased with MAT in the range of 15–23 °C, and the effective value of MAWS was in the range of 1.3–1.7 m/s, which was positively correlated with incidences of HFMD. Conclusions: HFMD incidence and climate factors were found to be spatiotemporally associated, and climate factors are mostly non-linearly associated with HFMD incidence.


2019 ◽  
Vol 171 ◽  
pp. 104766 ◽  
Author(s):  
Anna Munsey ◽  
Frank Norbert Mwiine ◽  
Sylvester Ochwo ◽  
Lauro Velazquez-Salinas ◽  
Zaheer Ahmed ◽  
...  

2018 ◽  
Vol 66 (2) ◽  
pp. 653-661 ◽  
Author(s):  
Manuel José Sanchez‐Vazquez ◽  
Lia Puppim Buzanovsky ◽  
Alexandre Guerra dos Santos ◽  
Rossana Maria Allende ◽  
Ottorino Cosivi ◽  
...  

2021 ◽  
Vol 53 (3) ◽  
Author(s):  
Mohamed Mahmoud Sirdar ◽  
Geoffrey Theodore Fosgate ◽  
Belinda Blignaut ◽  
Lucas R. Mampane ◽  
Oupa Boetie Rikhotso ◽  
...  

Author(s):  
Sydney S. Breese ◽  
Howard L. Bachrach

Continuing studies on the physical and chemical properties of foot-and-mouth disease virus (FMDV) have included electron microscopy of RNA strands released when highly purified virus (1) was dialyzed against demlneralized distilled water. The RNA strands were dried on formvar-carbon coated electron microscope screens pretreated with 0.1% bovine plasma albumin in distilled water. At this low salt concentration the RNA strands were extended and were stained with 1% phosphotungstic acid. Random dispersions of strands were recorded on electron micrographs, enlarged to 30,000 or 40,000 X and the lengths measured with a map-measuring wheel. Figure 1 is a typical micrograph and Fig. 2 shows the distributions of strand lengths for the three major types of FMDV (A119 of 6/9/72; C3-Rezende of 1/5/73; and O1-Brugge of 8/24/73.


Author(s):  
S. S. Breese ◽  
H. L. Bachrach

Models for the structure of foot-and-mouth disease virus (FMDV) have been proposed from chemical and physical measurements (Brown, et al., 1970; Talbot and Brown, 1972; Strohmaier and Adam, 1976) and from rotational image-enhancement electron microscopy (Breese, et al., 1965). In this report we examine the surface structure of FMDV particles by high resolution electron microscopy and compare it with that of particles in which the outermost capsid protein VP3 (ca. 30, 000 daltons) has been split into smaller segments, two of which VP3a and VP3b have molecular weights of about 15, 000 daltons (Bachrach, et al., 1975).Highly purified and concentrated type A12, strain 119 FMDV (5 mg/ml) was prepared as previously described (Bachrach, et al., 1964) and stored at 4°C in 0. 2 M KC1-0. 5 M potassium phosphate buffer at pH 7. 5. For electron microscopy, 1. 0 ml samples of purified virus and trypsin-treated virus were dialyzed at 4°C against 0. 2 M NH4OAC at pH 7. 3, deposited onto carbonized formvar-coated copper screens and stained with phosphotungstic acid, pH 7. 3.


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