Chelating extraction of metals from e-waste using diethylene triamine pentaacetic acid

2019 ◽  
Vol 121 ◽  
pp. 1-11 ◽  
Author(s):  
Auchitya Verma ◽  
Subrata Hait
Blood ◽  
1964 ◽  
Vol 23 (3) ◽  
pp. 321-336 ◽  
Author(s):  
H. S. WINCHELL ◽  
MYRON POLLYCOVE ◽  
A. C. ANDERSEN ◽  
J. H. LAWRENCE

Abstract In an attempt to provide relatively selective irradiation of tissues responsible for the homograft rejection response and to minimize exposure of other radiosensitive tissues, we developed a technic using internally administered Yttrium-90 chelated with DTPA (diethylene triamine-pentaacetic acid). Dogs given sublethal doses of Y90-DTPA radiation had a benign clinical course, the only remarkable finding being a selective lymphopenia without depression of granulocytes, platelets, or reticulocytes. Dogs lethally irradiated with Y90-DTPA showed depression of all formed blood elements, and severe depression of lymphocytes was most prominent. As the homograft rejection response appears to be a function of lymphatic tissues, the results obtained suggest the use of this procedure to prepare large mammals for homologous tissue transplantation.


Neurosurgery ◽  
2011 ◽  
Vol 69 (3) ◽  
pp. 668-676 ◽  
Author(s):  
John H Sampson ◽  
Martin Brady ◽  
Raghu Raghavan ◽  
Ankit I Mehta ◽  
Allan H Friedman ◽  
...  

Abstract BACKGROUND: Convection-enhanced delivery (CED) permits site-specific therapeutic drug delivery within interstitial spaces at increased dosages through circumvention of the blood-brain barrier. CED is currently limited by suboptimal methodologies for monitoring the delivery of therapeutic agents that would permit technical optimization and enhanced therapeutic efficacy. OBJECTIVE: To determine whether a readily available small-molecule MRI contrast agent, gadolinium-diethylene triamine pentaacetic acid (Gd-DTPA), could effectively track the distribution of larger therapeutic agents. METHODS: Gd-DTPA was coinfused with the larger molecular tracer, 124I-labeled human serum albumin (124I-HSA), during CED of an EGFRvIII-specific immunotoxin as part of treatment for a patient with glioblastoma. RESULTS: Infusion of both tracers was safe in this patient. Analysis of both Gd-DTPA and 124I-HSA during and after infusion revealed a high degree of anatomical and volumetric overlap. CONCLUSION: Gd-DTPA may be able to accurately demonstrate the anatomic and volumetric distribution of large molecules used for antitumor therapy with high resolution and in combination with fluid-attenuated inversion recovery (FLAIR) imaging, and provide additional information about leaks into cerebrospinal fluid spaces and resection cavities. Similar studies should be performed in additional patients to validate our findings and help refine the methodologies we used.


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