scholarly journals Alternatives to antibiotics for organic poultry production: types, modes of action and impacts on bird's health and production

2022 ◽  
pp. 101696
Author(s):  
Mohamed E. Abd El-Hack ◽  
Mohamed T. El-Saadony ◽  
Heba M. Salem ◽  
Amira M. El-Tahan ◽  
Mohamed M. Soliman ◽  
...  
Keyword(s):  
Poultry Production ◽  
Modes Of Action

Therapeutic options in male osteoporosis

2013 ◽  
Vol 22 (04) ◽  
pp. 271-276 ◽  
Author(s):  
P. Farahmand ◽  
J. D. Ringe
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Public Health Problem ◽  
Male Osteoporosis ◽  
Individual Risk ◽  
Modes Of Action ◽  
Increased Risk ◽  
Study Results ◽  
Long Term Treatment ◽  
Male Patients

SummaryOsteoporosis in men is increasingly recognized as an important public health problem but affected patients are still under-diagnosed and -treated. As in women the diagnostic and therapeutic strategy has to be adapted to the individual case. In the practical management it is very important to detect possible causes of secondary osteoporosis, to explain the possibilities of basic therapy counteracting individual risk factors and communicate that osteoporosis is a chronic disease and adherence to a long-term treatment is crucial. In established severe osteoporosis a careful analgesic therapy is important to avoid further bone loss related to immobility. In elderly men with increased risk of falling insufficient Vitamin D supply or impaired activation of Vitamin D due to renal insufficiency must be taken into consideration. Specific medications available today for the treatment of male osteoporosis comprise among antiresorptive drugs the bis phosphonates alendronate, risedronate and zoledronic acid. Denosumab, the first biological therapy is approved for men with androgen deprivation therapy for prostate cancer. An important advantage of this potent antiresorptive drug is the increased adherence due to the comfortable application by sixmonthly subcutaneous injections. Study results from the 2-year multi-center randomized controlled ADAMO-Study will very soon allow the use of denosumab in all types of male osteoporosis. Teriparatide, the 34 N-terminal amino acid sequence of parathyroid hormone was approved for men with osteoporosis as an anabolic agent based on proven efficacy by different studies. Among drugs with other modes of action the D-hormone pro-drug alfacalcidol can be used in men alone or in combination with the advantage of pleiotropic effects on calcium absorption, parathyroids, bone and muscle. Recently also Strontium-ranelate was approved for male patients with the limitation to exclude men with clinical relevant cardiovascular risk factors. In general the possibilities to treat male osteoporosis have considerably improved during recent years. Today there is a choice of a spectrum of drugs from mild to strong potency with different modes of action on bone turnover to design strategies for individual male patients.

Pesticides Modes of Action and Resistance: A Perspective from the 2019 IUPAC Congress

2019 ◽  
Vol 30 (4) ◽  
pp. 157-163 ◽  
Author(s):  
Franck E. Dayan ◽  
Geert Haesaert ◽  
Thomas Van Leeuwen ◽  
Lindy Holden-Dye ◽  
Andrew Crossthwaite ◽  
...  
Keyword(s):  
Modes Of Action

NEW GENERATION FEED ADDITIVE IN POULTRY BREEDING

1970 ◽  
pp. 67-69
Author(s):  
L. I. Naumova ◽  
М. Т. Klychnikov ◽  
N. F. Klychnikova
Keyword(s):  
Laying Hens ◽  
Far East ◽  
Brown Seaweed ◽  
Test Group ◽  
Live Weight ◽  
Production Quality ◽  
Feed Additive ◽  
Poultry Production ◽  
Omega 3 ◽  
Mineral Substances

The analysis of different doses of complex feed additive to poultry ration have been made. The influence of new feed additive with bioresources of the Far East use on productive poultry indexes, on production quality and digestibility of nutritious matters of mixed feed has been studied. Patrinia scabiosifolia, Acanthopanax sesseliflorum, cones of cedare nut husk, brown seaweed, macro- and microelements, vitamins were the object of research. As a result of these researches author presents more effective norms of complex feed additive use in poultry farming of Khabarovsk Kray. The recipe of feed additive from local vegetable resources and complex of vitamins and minerals for use in laying hens nutrition was worked out. The aim of this work was to rise zootechnic and economic indexes of poultry production. The introduction of complex feed additive in ration influenced positively on the digestibility, raised the content of Omega-3 fat acid in egg of laying hens. The increase of Omega-3 fat acid quantity promotes decrease of cholesterol in yolk of egg. In the experimental groups there was a more intensive use of nutrients in diet, mainly due to raw protein, fats, mineral substances – calcium and phosphorus. The use of a new feed additive had a positive effect on the hatchability of eggs, the development of internal organs (heart, liver) and the live weight of chicks obtained from the eggs of chickens in experimental groups. Additionally, the content of mineral substances (calcium, potassium, phosphorus) in the egg of test group was higher than in the control on average by 2.3-5.1%.

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