Electroconvulsive therapy increases glial cell-line derived neurotrophic factor (GDNF) serum levels in patients with drug-resistant depression

2009 ◽  
Vol 170 (2-3) ◽  
pp. 273-275 ◽  
Author(s):  
Xiaobin Zhang ◽  
Zhijun Zhang ◽  
Weiwei Sha ◽  
Chunming Xie ◽  
Guangjun Xi ◽  
...  
Keyword(s):  
Cell Line ◽  
Glial Cell ◽  
Electroconvulsive Therapy ◽  
Neurotrophic Factor ◽  
Serum Levels ◽  
Drug Resistant ◽  
Resistant Depression

Association between serum levels of glial cell-line derived neurotrophic factor and attention deficits in schizophrenia

2014 ◽  
Vol 575 ◽  
pp. 37-41 ◽  
Author(s):  
Tomihisa Niitsu ◽  
Yukihiko Shirayama ◽  
Daisuke Matsuzawa ◽  
Eiji Shimizu ◽  
Kenji Hashimoto ◽  
...  
Keyword(s):  
Cell Line ◽  
Glial Cell ◽  
Neurotrophic Factor ◽  
Serum Levels ◽  
Attention Deficits

Serum levels of glial cell line-derived neurotrophic factor as a biomarker for mood disorders and lithium response

2021 ◽  
pp. 113967
Author(s):  
Keita Idemoto ◽  
Tomihisa Niitsu ◽  
Tatsuki Hata ◽  
Tamaki Ishima ◽  
Sumiko Yoshida ◽  
...  
Keyword(s):  
Cell Line ◽  
Mood Disorders ◽  
Glial Cell ◽  
Neurotrophic Factor ◽  
Serum Levels ◽  
Lithium Response

scholarly journals Serum levels of BDNF are associated with craving in opiate-dependent patients

2011 ◽  
Vol 25 (11) ◽  
pp. 1480-1484 ◽  
Author(s):  
Annemarie Heberlein ◽  
Kenneth M Dürsteler-MacFarland ◽  
Bernd Lenz ◽  
Helge Frieling ◽  
Michael Grösch ◽  
...  
Keyword(s):  
Cell Line ◽  
Glial Cell ◽  
Neurotrophic Factor ◽  
Positive Association ◽  
Serum Levels ◽  
Brain Derived Neurotrophic Factor ◽  
Preclinical Study ◽  
Healthy Controls ◽  
Addictive Behaviour ◽  
Study Results

Preclinical study results suggest that brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) are involved in the modulation of addictive behaviour. We investigated alterations in serum levels of BDNF and GDNF in opiate-dependent patients (28 males) who received diacetylmorphine treatment within a structured opiate maintenance programme. BDNF ( T = 2.735, p = 0.009) serum levels were significantly increased in the opiate-dependent patients as compared with healthy controls (21 males), whereas GDNF serum levels ( T = 1.425, p = 0.162) did not differ significantly from GDNF serum levels of the healthy controls. BDNF serum levels were significantly associated with craving for heroin (measured by the Heroin Craving Questionnaire ( r = 0.420, p = 0.029) and by the General Craving Scale ( r = 0.457, p = 0.016), whereas GDNF serum levels were not associated with psychometric dimensions of heroin craving. In conclusion, our results show a positive association between BDNF serum levels and opiate craving in opiate-dependent patients.

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