Comparison of psychopathological dimensions between major depressive disorder and schizophrenia spectrum disorders focusing on language, affectivity and motor behavior

BackgroundThe elderly population and numbers of nursing homes residents are growing at a rapid pace globally. Uncertainty exists regarding the actual rates of major depressive disorder (MDD), bipolar disorder and schizophrenia as previous evidence documenting high rates relies on suboptimal methodology.AimsTo carry out a systematic review and meta-analysis on the prevalence and correlates of MDD, bipolar disorder and schizophrenia spectrum disorder among nursing homes residents without dementia.MethodMajor electronic databases were systematically searched from 1980 to July 2017 for original studies reporting on the prevalence and correlates of MDD among nursing homes residents without dementia. The prevalence of MDD in this population was meta-analysed through random-effects modelling and potential sources of heterogeneity were examined through subgroup/meta-regression analyses.ResultsAcross 32 observational studies encompassing 13 394 nursing homes residents, 2110 people were diagnosed with MDD, resulting in a pooled prevalence rate of 18.9% (95% CI 14.8–23.8). Heterogeneity was high (I2 = 97%, P≤0.001); no evidence of publication bias was observed. Sensitivity analysis indicated the highest rates of MDD among North American residents (25.4%, 95% CI 18–34.5, P≤0.001). Prevalence of either bipolar disorder or schizophrenia spectrum disorder could not be reliably pooled because of the paucity of data.ConclusionsMDD is highly prevalent among nursing homes residents without dementia. Efforts towards prevention, early recognition and management of MDD in this population are warranted.

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Depressive psychopathology in first-episode schizophrenia spectrum disorders: a systematic review, meta-analysis and meta-regression

Psychological Medicine ◽

10.1017/s0033291719002344 ◽

2019 ◽

Vol 49 (15) ◽

pp. 2463-2474 ◽

Cited By ~ 5

Author(s):

Sarah E. Herniman ◽

Kelly Allott ◽

Lisa J. Phillips ◽

Stephen J. Wood ◽

Jacqueline Uren ◽

...

Keyword(s):

Systematic Review ◽

Depressive Disorder ◽

Meta Analysis ◽

First Episode ◽

Schizophrenia Spectrum Disorders ◽

Schizophrenia Spectrum ◽

Pooled Prevalence ◽

Meta Regression ◽

Spectrum Disorders ◽

First Episode Schizophrenia

AbstractBackgroundDespite knowing for many decades that depressive psychopathology is common in first-episode schizophrenia spectrum disorders (FES), there is limited knowledge regarding the extent and nature of such psychopathology (degree of comorbidity, caseness, severity) and its demographic, clinical, functional and treatment correlates. This study aimed to determine the pooled prevalence of depressive disorder and caseness, and the pooled mean severity of depressive symptoms, as well as the demographic, illness, functional and treatment correlates of depressive psychopathology in FES.MethodsThis systematic review, meta-analysis and meta-regression was prospectively registered (CRD42018084856) and conducted in accordance with PRISMA and MOOSE guidelines.ResultsForty studies comprising 4041 participants were included. The pooled prevalence of depressive disorder and caseness was 26.0% (seven samples, N = 855, 95% CI 22.1–30.3) and 43.9% (11 samples, N = 1312, 95% CI 30.3–58.4), respectively. The pooled mean percentage of maximum depressive symptom severity was 25.1 (38 samples, N = 3180, 95% CI 21.49–28.68). Correlates of depressive psychopathology were also found.ConclusionsAt least one-quarter of individuals with FES will experience, and therefore require treatment for, a full-threshold depressive disorder. Nearly half will experience levels of depressive symptoms that are severe enough to warrant diagnostic investigation and therefore clinical intervention – regardless of whether they actually fulfil diagnostic criteria for a depressive disorder. Depressive psychopathology is prominent in FES, manifesting not only as superimposed comorbidity, but also as an inextricable symptom domain.

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MOTOR BEHAVIOR ABNORMALITIES IN DRUG-NAïVE PATIENTS WITH SCHIZOPHRENIA SPECTRUM DISORDERS

Schizophrenia Research ◽

10.1016/j.schres.2010.02.239 ◽

2010 ◽

Vol 117 (2-3) ◽

pp. 187-188

Author(s):

Virginia Basterra ◽

Ana M. Sanchez-Torres ◽

Manuel J. Cuesta ◽

Victor Peralta

Keyword(s):

Motor Behavior ◽

Schizophrenia Spectrum Disorders ◽

Schizophrenia Spectrum ◽

Drug Naïve ◽

Spectrum Disorders

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Patient Reflections on Individual Music Therapy for a Major Depressive Disorder or Acute Phase Schizophrenia Spectrum Disorder

Journal of Music Therapy ◽

10.1093/jmt/thaa001 ◽

2020 ◽

Vol 57 (2) ◽

pp. 168-192

Author(s):

Natalie Paul ◽

Carol Lotter ◽

Werdie van Staden

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Music Therapy ◽

Acute Phase ◽

Evidence Base ◽

Spectrum Disorder ◽

Schizophrenia Spectrum Disorder ◽

Major Depressive ◽

Schizophrenia Spectrum ◽

Receptive Music Therapy

Abstract Reflections of patients have not been studied qualitatively after a completed course of individual music therapy for a major depressive disorder (MDD) or an acute phase of a schizophrenia spectrum disorder (SSD). Our interpretivist study explored patient reflections through individual interviews with 15 hospitalized patients after a completed course of eight individual music therapy sessions that were flexibly structured in blended fashion utilizing a set of active and receptive music therapy methods. Our analyses yielded 8 themes, supported by 23 subthemes. These themes were grouped into three domains, capturing respectively participants’ praise for music therapy, the distress from which change emerged, and various perceived gains. Participants cast the perceived gains from music therapy in the wake of their distress. The domain of distress comprised two themes: distress before and during therapy, and a process of opening up and dealing with old wounds. The themes expressing their gains were: new perspectives, growing strong, emotional fulfillment, becoming socially closer and more adept, and becoming liberated and creatively inspired. These client perspectives on a completed course of music therapy augment the evidence base established in clinician terms of what matters as a potential gain from music therapy. These perspectives, furthermore, inform on the gains and the distress from which gains emerged, congruent with a strengths-oriented therapeutic pursuit in music therapy for an MDD or an acute phase of SSD. Music therapists in similar settings may draw on these perspectives in the planning and strengthening of a course of music therapy.

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Depressive disorder and depression within schizophrenia spectrum disorders: are they the same?]

Anales del Sistema Sanitario de Navarra ◽

10.23938/assn.0849 ◽

2009 ◽

Author(s):

V. Peralta

Keyword(s):

Depressive Disorder ◽

Schizophrenia Spectrum Disorders ◽

Schizophrenia Spectrum ◽

Spectrum Disorders

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The Phenomenology of Anomalous World Experience in Schizophrenia: A Qualitative Study

Journal of Phenomenological Psychology ◽

10.1163/15691624-12341328 ◽

2017 ◽

Vol 48 (2) ◽

pp. 188-213 ◽

Cited By ~ 2

Author(s):

Elizabeth Pienkos ◽

Steven Silverstein ◽

Louis Sass

Keyword(s):

Depressive Disorders ◽

Comparison Group ◽

Pilot Project ◽

Phenomenological Method ◽

Schizophrenia Spectrum Disorders ◽

Subjective Experiences ◽

Major Depressive ◽

Schizophrenia Spectrum ◽

The World ◽

Spectrum Disorders

AbstractThis current study is a pilot project designed to clarify changes in the lived world among people with diagnoses within the schizophrenia spectrum. The Examination of Anomalous World Experience (eawe) was used to interview ten participants with schizophrenia spectrum disorders (sz) and a comparison group of three participants with major depressive disorder (dep). Interviews were analyzed using the descriptive phenomenological method. This analysis revealed two complementary forms of experience unique toszparticipants: Destabilization, the experience that reality and the intersubjective world are less comprehensible, less stable, and generally less real; and Subjectivization, the dominance of one’s internal, subjective experiences in the perception or interpretation of the lived world. Persons with depressive disorders, by contrast, did not experience disruptions of the reality or independence of the world or any significant disruptions of appearance or meaning. These results are consistent with contemporary and classic phenomenological views on anomalous world experience in schizophrenia.

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