Role of chest CT scan in atypical cardiac trauma management: Left ventricle injury by a nail gun

Abstract Background and purpose Fatty liver is one of the most common pre-existing illnesses; it can cause liver injury, leading to further complications in coronavirus disease 2019 patients. Our goal is to determine if pre-existing fatty liver is more prevalent in hospitalized COVID-19 patients compared to patients admitted before the SARS-CoV-2 pandemic and determine the disease severity among fatty liver patients. Experimental approach This retrospective study involves a case and a control group consisting of 1162 patients; the case group contains hospitalized COVID-19 patients with positive PCR tests and available chest CT-scan; the control group contains patients with available chest CT-scan previous to the COVID-19 pandemic. Patients’ data such as liver Hounsfield unit, hospitalization length, number of affected lobes, and total lungs involvement score were extracted and compared between the patients. Results The findings indicate that 37.9% of hospitalized COVID-19 patients have a pre-existing fatty liver, which is significantly higher (P < 0.001) than the prevalence of pre-existing fatty liver in control group patients (9.02%). In comparison to hospitalized non-fatty liver COVID-19 patients, data from hospitalized COVID-19 patients with fatty liver indicate a longer hospitalization length (6.81 ± 4.76 P = 0.02), a higher total lungs involvement score (8.73 ± 5.28 P < 0.001), and an increased number of affected lobes (4.42 ± 1.2 P < 0.001). Conclusion The statistical analysis shows fatty liver is significantly more prevalent among COVID-19 against non-COVID-19 patients, and they develop more severe disease and tend to be hospitalized for more extended periods.

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The Role of Fever Clinic During the COVID-19 Pandemic: A case study of 1034 febrile patients

10.21203/rs.3.rs-25353/v1 ◽

2020 ◽

Cited By ~ 1

Author(s):

Li Tang ◽

Yanxia He ◽

Fangjing Bai ◽

Bin Luo

Keyword(s):

Body Temperature ◽

Ct Scan ◽

Sore Throat ◽

Chest Ct ◽

Entire World ◽

Isolation Ward ◽

Chest Ct Scan ◽

Clinic Visits

Abstract Background Since winter of 2019, when coronavirus disease 2019 (Covid-19) emerged in China and rapidly spread throughout the entire world, many fever clinics were rearranged and enlarged to triage febrile patients in China. Methods This study included fever clinic visits of Sichuan Provincial Peoples’ Hospital to summarize the characteristics of these febrile patients retrospectively. Results From 24th January to 31th March, 1034 fever clinic visits with 530 male and 504 female, were triaged, treated and recorded. About 64.9% of them were checked with body temperature higher than 37.3℃. Cough (25.0%) and sore throat (19.2%) were the most common symptoms in addition to fever. Chest CT scan was ordered for 900 patients, and 172 cases (16.6%) were found ground grass opacity, 134 (13.0%) found local patchy shadowing, and 26 (2.5%) found bilateral patchy shadowing. At last 851 patients (82.3%) were excluded for COVID-19 or other severe diseases. Eighty patients (7.7%) were admitted to hospitalization for other conditions. One hundred and three (9.9%) patients were suspected or confirmed of COVID-19 at fever clinic, and then admitted to isolation ward. Conclusions The result of this study again verified the extraordinary role of fever clinics in pandemics. When confronted with a mass of unknown febrile patients, a well organized fever clinic may avoid the frustration of all medical staffs.

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Independent role of CT chest scan in COVID-19 prognosis: Evidence from the machine learning classification

SCRIPTA MEDICA ◽

10.5937/scriptamed52-34457 ◽

2021 ◽

Vol 52 (4) ◽

pp. 273-278

Author(s):

Sudhir Bhandari ◽

Shaktawat Singh ◽

Amit Tak ◽

Bhoopendra Patel ◽

Jitentdra Gupta ◽

...

Keyword(s):

Support Vector Machine ◽

Ct Scan ◽

Principal Components ◽

Severity Score ◽

Feature Space ◽

Chest Ct ◽

Support Vector ◽

Machine Learning Classification ◽

Chest Ct Scan

Background: The current coronavirus disease-19 (COVID-19) pandemic call attention to the key role informatics play in healthcare. The present study discovers an independent role of computerised tomography chest (CT) scans in prognosis of COVID-19 using classification learning algorithms. Methods: In this retrospective study, 57 RT PCR positive COVID-19 patients were enrolled from SMS Medical College, Jaipur (Rajasthan, India) after approval from the Institutional Ethics Committee. A set of 21 features including clinical findings and laboratory parameters and chest CT severity score were recorded. The CT score with mild, moderate and severe categories was chosen as response variable. The dimensionality reduction of feature space was performed and classifiers including, decision trees, K-nearest neighbours, support vector machine and ensemble learning were trained with principal components. The model with highest accuracy and area under the ROC curve (AUC) was selected. Results: The median age of patients was 55 years (range: 20-99 years) with 37 males. The feature space was reduced from 21 to 7 predictors, that included fever, cough, fibrin degradation products, haemoglobin, neutrophil-lymphocyte ratio, ferritin and procalcitonin. The linear support vector machine was chosen as the best classifier with 73.7 % and 0.69 accuracy and AUC for severe CT chest score, respectively. The variance contributed by first three principal components were 97.5 %, 2.4 % and 0.0 %, respectively. Conclusion: In view of low degree of relationships between predictors and chest CT scan severity score category as interpreted from accuracy and AUC it can be concluded that chest CT scan has an independent role in the prognosis of COVID-19 patients.

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Role of chest CT scan in the initial management of chest injuries in polytrauma patients

Injury Extra ◽

10.1016/j.injury.2006.12.050 ◽

2007 ◽

Vol 38 (4) ◽

pp. 109

Author(s):

V. Gowda ◽

V. Majuran ◽

S. Bradley ◽

K. Porter

Keyword(s):

Ct Scan ◽

Chest Ct ◽

Initial Management ◽

Chest Injuries ◽

Polytrauma Patients ◽

Chest Ct Scan

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The Role of Repeat Chest CT Scan in the COVID-19 Pandemic

Academic Radiology ◽

10.1016/j.acra.2020.04.031 ◽

2020 ◽

Vol 27 (7) ◽

pp. 1049-1050 ◽

Cited By ~ 1

Author(s):

Ali Mahdavi ◽

Sara Haseli ◽

Arash Mahdavi ◽

Mehrdad Bakhshayeshkaram ◽

Morteza Foroumandi ◽

...

Keyword(s):

Ct Scan ◽

Chest Ct ◽

Repeat Chest ◽

Chest Ct Scan

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Typical, rare and atypical CT findings in COVID-19 pneumonia: A pictorial review

Journal of Clinical Images and Medical Case Reports ◽

10.52768/2766-7820/1248 ◽

2021 ◽

Vol 2 (4) ◽

Author(s):

Charlotte M Biebaû ◽

◽

Adriana Dubbeldam ◽

Johan Coolen ◽

Johny A Verschakelen ◽

...

Keyword(s):

Ct Scan ◽

Daily Practice ◽

Chest Ct ◽

Ct Findings ◽

Pictorial Review ◽

Risk Of Disease ◽

X Ray Computed ◽

Test Probability ◽

Chest Ct Scan

Objectives: The objective of this pictorial review is to make radiologists and clinicians familiar with the typical, atypical and rare CT findings of COVID-19 pneumonia to help in diagnosis as well as in monitoring disease. Main text: Bilateral ground-glass opacities, whether isolated or coexisting with consolidations, and typically in basal, posterior and peripheral lungs are the key findings in COVID-19 pneumonia. With further analysis other typical, atypical and rare CT findings are described and we need to keep in mind that the radiological presentation is dynamic with a rapid evolutive phase, peaking at 10-11 days, and a subsequent absorption phase after 14 days with a decrease in opacities and increase in repairing signs. Conclusion: The presence of typical findings of COVID-19 pneumonia on a chest CT scan during the pandemic outbreak of SARSCoV-2 helps in diagnostic analysis. Chest CT scan has a reported sensitivity of 97-98% in times with a high pre-test probability. Some CT findings (crazy paving pattern and pleural effusion) as well as an increasing percentage of lung opacities are associated with a worse patient outcome, emphasizing the role of chest CT in determining the risk of disease progression. Furthermore chest CT scan is also useful in monitoring disease control. With these acknowledgement we want to give a useful overview of the chest CT manifestations in COVID-19 pneumonia to help decision making in daily practice. Keywords: COVID-19; SARS-CoV-2; tomography; X Ray computed; diagnosis.

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538. The Role of N-acetylcysteine on Post Covid-19 Pulmonary Fibrosis

Open Forum Infectious Diseases ◽

10.1093/ofid/ofab466.737 ◽

2021 ◽

Vol 8 (Supplement_1) ◽

pp. S370-S371

Author(s):

Bernard Demot ◽

Kristin Ivan Mark Hizon

Keyword(s):

Pulmonary Fibrosis ◽

Ct Scan ◽

Chest Ct ◽

Ct Scans ◽

Ground Glass ◽

Nasopharyngeal Swab ◽

High Dose ◽

Pulmonary Consolidation ◽

Chest Ct Scan

Abstract Background Covid 19 have long lasting complications, from myalgia, body weakness to life debilitating strokes, and pulmonary fibrosis. Several mechanisms had been described but mostly viral or autoimmune which causes damages which leads to Acute respiratory distress syndrome. There is no approved treatment as of this time. Antifibrotic drugs use had been limited due to hepatoxicity, on top of Covid 19 hepatopathy. This study aims to describe the role of N-acetylcysteine on Post COVID 19 pulmonary fibrosis as an alternative treatment. Methods Patients are admitted at Baguio General Hospital and Medical Center at the COVID wards. Patients are COVID confirmed by RT PCR nasopharyngeal swab. Patient who are classified as severe were given Dexamethasone, Enoxaparin and Remdesivir for 5-10 days. Patients who are not weaned off from O2 support underwent Chest CT scan. Patients with Extensive Fibrosis were then consented to undergo High Dose IV Infusion of N-acetylcysteine. (150mg/kg in 1st hour, 50mg/kg next 4 hours and 100mg/kg last 20 hours). Repeat Chest CT Scan was done. Results Peripheral Bilateral Ground Glass Opacities and Pulmonary Consolidation was seen on pre-treatment CT Scans. Repeat CT scans showed significant regression of Ground Glass Opacities and Pulmonary Consolidation. CT SCAN pre and post treatment Conclusion High dose N-acetylcysteine showed promising results on Post COVID 19 Pulmonary Fibrosis. Disclosures All Authors: No reported disclosures

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The Role of Fever Clinic During the COVID-19 Pandemic: A Case Study of 1034 Febrile Patients

10.21203/rs.3.rs-28368/v1 ◽

2020 ◽

Cited By ~ 1

Author(s):

Li Tang ◽

Yanxia He ◽

Fangjing Bai ◽

Bin Luo

Keyword(s):

Body Temperature ◽

Ct Scan ◽

Sore Throat ◽

Chest Ct ◽

Entire World ◽

Isolation Ward ◽

Chest Ct Scan ◽

Clinic Visits

Abstract Background Since winter of 2019, when coronavirus disease 2019 (Covid-19) emerged in China and rapidly spread throughout the entire world, many fever clinics were rearranged and enlarged to triage febrile patients in China.Methods This study included fever clinic visits of Sichuan Provincial Peoples’ Hospital to summarize the characteristics of these febrile patients retrospectively.Results From 24th January to 31th March, 1034 fever clinic visits with 530 male and 504 female, were triaged, treated and recorded. About 64.9% of them were checked with body temperature higher than 37.3℃. Cough (25.0%) and sore throat (19.2%) were the most common symptoms in addition to fever. Chest CT scan was ordered for 900 patients, and 172 cases (16.6%) were found ground grass opacity, 134 (13.0%) found local patchy shadowing, and 26 (2.5%) found bilateral patchy shadowing. At last 851 patients (82.3%) were excluded for COVID-19 or other severe diseases. Eighty patients (7.7%) were admitted to hospitalization for other conditions. One hundred and three (9.9%) patients were suspected or confirmed of COVID-19 at fever clinic, and then admitted to isolation ward.Conclusions The result of this study again verified the extraordinary role of fever clinics in pandemics. When confronted with a mass of unknown febrile patients, a well organized fever clinic may avoid the frustration of all medical staffs.

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Cancer surgery during the COVID‐19 pandemic: The experience of a comprehensive cancer center performing preoperative screening by RT‐PCR and chest CT scan

Journal of Surgical Oncology ◽

10.1002/jso.26335 ◽

2021 ◽

Vol 123 (4) ◽

pp. 815-822

Author(s):

Joanne Guerlain ◽

Fabienne Haroun ◽

Alexandra Voicu ◽

Charles Honoré ◽

Franck Griscelli ◽

...

Keyword(s):

Ct Scan ◽

Chest Ct ◽

Cancer Surgery ◽

Comprehensive Cancer Center ◽

Cancer Center ◽

Preoperative Screening ◽

Rt Pcr ◽

Chest Ct Scan

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A meta-analysis of accuracy and sensitivity of chest CT and RT-PCR in COVID-19 diagnosis

Scientific Reports ◽

10.1038/s41598-020-80061-2 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Fatemeh Khatami ◽

Mohammad Saatchi ◽

Seyed Saeed Tamehri Zadeh ◽

Zahra Sadat Aghamir ◽

Alireza Namazi Shabestari ◽

...

Keyword(s):

Polymerase Chain Reaction ◽

Reverse Transcriptase ◽

Ct Scan ◽

Predictive Value ◽

Meta Analysis ◽

Chest Ct ◽

Rt Pcr ◽

Chain Reaction ◽

Polymerase Chain ◽

Chest Ct Scan

AbstractNowadays there is an ongoing acute respiratory outbreak caused by the novel highly contagious coronavirus (COVID-19). The diagnostic protocol is based on quantitative reverse-transcription polymerase chain reaction (RT-PCR) and chests CT scan, with uncertain accuracy. This meta-analysis study determines the diagnostic value of an initial chest CT scan in patients with COVID-19 infection in comparison with RT-PCR. Three main databases; PubMed (MEDLINE), Scopus, and EMBASE were systematically searched for all published literature from January 1st, 2019, to the 21st May 2020 with the keywords "COVID19 virus", "2019 novel coronavirus", "Wuhan coronavirus", "2019-nCoV", "X-Ray Computed Tomography", "Polymerase Chain Reaction", "Reverse Transcriptase PCR", and "PCR Reverse Transcriptase". All relevant case-series, cross-sectional, and cohort studies were selected. Data extraction and analysis were performed using STATA v.14.0SE (College Station, TX, USA) and RevMan 5. Among 1022 articles, 60 studies were eligible for totalizing 5744 patients. The overall sensitivity, specificity, positive predictive value, and negative predictive value of chest CT scan compared to RT-PCR were 87% (95% CI 85–90%), 46% (95% CI 29–63%), 69% (95% CI 56–72%), and 89% (95% CI 82–96%), respectively. It is important to rely on the repeated RT-PCR three times to give 99% accuracy, especially in negative samples. Regarding the overall diagnostic sensitivity of 87% for chest CT, the RT-PCR testing is essential and should be repeated to escape misdiagnosis.

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