The effects of combined general and epidural anaesthesia with ropivacaine on stress hormone response versus general anaesthesia in total abdominal hysterectomy

2005 ◽  
Vol 30 (5) ◽  
pp. 51-51
Author(s):  
E KOC ◽  
G SIVRIKAYA ◽  
H DOBRUCALI ◽  
A HANCI ◽  
B YILMAZ
2019 ◽  
Author(s):  
Ahmed Abdalla Mohamed ◽  
Gehan Helmy Ibrahim ◽  
Nesrine Abd Elrahman El Refai ◽  
Tamer Mousaad Abdelhamid Gamaleldin ◽  
Reham Ali Abdelrahman Abdelrahman ◽  
...  

Abstract Background: preoperative oral pregabalin controls postoperative pain & decreases anesthetic requirements in total intravenous anaesthesia . In this study, we hypothesized that preoperative pregabalin reduces inhaled isoflurane requirements. Methods: Study was conducted in a university hospital, included 50 women (18-60 yrs.), ASA I or II, admitted to undergo elective abdominal hysterectomy under general anaesthesia. Time of study: June to September 2017. Exclusion criteria were allergy or hypersensitivity to pregabalin; patients on calcium channel blockers, antiepileptic drugs, antidepression drugs, any analgesics or sedatives, or oral hypoglycemic agents; and patients with severe cardiovascular, renal, hepatic or neurological dysfunction. Interventions: giving either oral pregabalin 150 mg or placebo to patients of both groups. Primary outcome measures: inhaled isoflurane requirements to maintain haemodynamics ± 20% of baseline& bispectral index (BIS) of 40 - 60, measured using MAQUET Flow-I anaesthetic machine. Secondary outcomes : attenuation of pressor response to intubation, postoperative pain, first time for rescue analgesia, total anaglesics and adverse effects. Results: Isoflurane consumption was significantly less in pregabalin group (7.80 ± 1.27ml h -1) versus (12.27 ± 2.49 ml h-1) in control group, (P= 0.00). Better haemodynamic stability was in pregabalin group after intubation. First postoperative hour :the mean VAS score was significantly higher in control group (7.10 ± 1.20) compared to pregabalin group (4.50 ± 1.70), P<0.001. All patients in control group received pethidine intramuscular. More patients in pregabalin group suffered dizziness. Conclusion: preoperative pregabalin 150 mg ,1 h before total abdominal hysterectomy has an inhaled anaesthetic-sparing effect, maintain haemodynamics and optimizes postoperative analgesia. Keywords: Gabapentinoids, Pregabalin; Inhalation Anaesthetics, Isoflurane; Monitoring, Bispectral Index; Surgery, Abdominal Hysterectomy Objectives: We aimed to investigate the effectiveness and safety of preoperative oral pregabalin 150 mg in women undergoing elective total abdominal hysterectomy under general anaesthesia. Design: A prospective, randomized, double-blind, controlled study. Trial Registry Number: ClinicalTrials.gov: NCT 03302208


2014 ◽  
Vol 24 (1) ◽  
pp. 18-22
Author(s):  
KK Karmakar ◽  
PC Sarker ◽  
Md M Islam ◽  
R Begum ◽  
MMA Wadud ◽  
...  

Background Post operative nausea and vomiting (PONV) is a common problem following general as well as regional anaesthesia. This causes great distress to the patient, may worsen surgical outcome and prolongs hospital stay. Prophylatic use of antiemetic in the preoperative or postoperative period reduces PONV. Objectives The study was designed to compare antiemetic effects of intravenous use of granisetron and ondansetron in the peroperative period for prevention of PONV following elective gynaecological surgery under general anaesthesia. Methods 60 (sixty) patients undergoing elective gynaecological surgery (total abdominal hysterectomy) under general anaesthesia of ASA grade I and II aged between 35-50 years were selected randomly and divided into two groups (group ‘O’ & group ‘G’) of thirty patients each. Patients of group ‘O’ received intravenous Inj, ondansetron 0.1 mg/kg body weight & group ‘G’ received intravenous Inj. granisetron 2 mg bolus over 30 sec just before peritoneal closure. Both the group received a standard general anaesthesia. Postoperative analgesia was provided with diclofenac suppository (50mg) and ketorolac tromethamine 30mg intra-muscularly. In the recovery room occurrence of post operative nausea and vomiting was assessed for 12 hours. All data were compiled and analyzed for statistical significance by Student’s ‘t’ tests (unpaired). P<0 .05 (CL 95%) was considered as significance. Results The incidence of post operative nausea and vomiting was reduced in both groups but no significant difference between the groups. No haemodynamic or psycho-mimetic adverse events were observed in the patients. DOI: http://dx.doi.org/10.3329/jbsa.v24i1.19795 Journal of Bangladesh Society of Anaesthesiologists 2011; 24(1): 18-22


Author(s):  
Jayshri Desai ◽  
Jayati Bhabutmal Jain ◽  
Venkata Suryanarayana Gopavajhula

Ebstein’s anomaly is considered to be one of the rare congenital heart conditions which occur due to abnormal development of tricuspid valve and atrialisation of right ventricle and could be associated with either Atrial Septal Defect (ASD) or Patent foramen ovale through which shunting occurs. It might be associated with other cardiac malformations and rhythm disturbances. In such a patient, clinical presentation varies from congestive cardiac failure in childhood to incidental diagnosis in adulthood. If such a patient comes for surgery, it will be a challenging job for anaesthesiologist. Various cases have been reported of successful management either under general anaesthesia or epidural anaesthesia. In order to avoid complications of general anaesthesia, in a case report of 40-year-old female to provide some knowledge and information on the use of subarachnoid block in the case of Ebstein’s Anomaly posted for total abdominal hysterectomy.


2021 ◽  
Vol 14 (2) ◽  
pp. e238945
Author(s):  
Olga Triantafyllidou ◽  
Stavroula Kastora ◽  
Irini Messini ◽  
Dimitrios Kalampokis

Subinvolution of placental sites (SPSs) is a rare but severe cause of secondary postpartum haemorrhage (PPH). SPS is characterised by the abnormal persistence of large, dilated, superficially modified spiral arteries in the absence of retained products of conception. It is an important cause of morbidity and mortality of young women. In this study, we present a case of secondary PPH in a young woman after uncomplicated caesarean delivery who was deemed clinically unstable, and finally, underwent emergent total abdominal hysterectomy. We reviewed the literature with an emphasis on the pathophysiology of this situation. Treatment of patients with SPS includes conservative medical therapy, hysterectomy and fertility-sparing percutaneous embolotherapy.


Author(s):  
Sunanda N.

Although leiomyomas are the most common pelvic tumors presenting in the reproductive age group, cervical fibroids are rare accounting for 2% of all uterine fibroids. We report a case of 40 year old lady presenting with a firm, non-tender mass of 22-24 weeks size pregnant uterus with restricted mobility. Laparotomy showed a large mass arising from the anterior lip of cervix, with a small uterus pushed posteriorly. Enucleation followed by total abdominal hysterectomy was done. Large cervical fibroids are rare, presenting with surgical difficulties. Careful dissection by expert hands is needed in the management of such cases. 


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