scholarly journals Surface modification of cotton-wool-like bone void fillers consisting of biodegradable polymer-based composite fibers containing calcium-salt particles

2021 ◽  
pp. 100236
Author(s):  
Masao Watabe ◽  
Takashi Matsubara ◽  
Akiko Obata ◽  
Yasutoshi Nishikawa ◽  
Toshihiro Kasuga
Keyword(s):  
Surface Modification ◽  
Biodegradable Polymer ◽  
Calcium Salt ◽  
Cotton Wool ◽  
Composite Fibers ◽  
Bone Void

Surface modification of titanium 6‐aluminum 7‐niobium alloy with biodegradable polymer coatings

2020 ◽  
Vol 51 (5) ◽  
pp. 613-623 ◽  
Author(s):  
J. Szewczenko ◽  
W. Kajzer ◽  
A. Kajzer ◽  
M. Basiaga ◽  
M. Kaczmarek ◽  
...  
Keyword(s):  
Surface Modification ◽  
Biodegradable Polymer ◽  
Polymer Coatings ◽  
Niobium Alloy ◽  
Modification Of Titanium

Cotton-Wool-Like Resorbable Bone Void Fillers Containing β-TCP and Calcium Carbonate Particles

2018 ◽  
Vol 782 ◽  
pp. 53-58 ◽  
Author(s):  
Naoki Osada ◽  
Masashi Makita ◽  
Yasutoshi Nishikawa ◽  
Toshihiro Kasuga
Keyword(s):  
Distal Femur ◽  
Cotton Wool ◽  
Micro Ct ◽  
New Bone Formation ◽  
Defect Sites ◽  
Electrospinning Method ◽  
New Zealand White Rabbits ◽  
Good Biocompatibility ◽  
Bone Void

Cotton-wool-like bioresorbable bone void fillers consisting of β-tricalcium phosphate (β-TCP), siloxane-containing vaterite (SiV) and poly (L-lactic acid) (PLLA) was prepared by an electrospinning method. The fibers, which were 50 ~ 150 μm-width with 10 ~ 30 μm-thickness, were entwined. The resulting cotton-wool-like material showed mechanical flexibility and excellent shapability; it showed easy, excellent mechanical-fixation in defects. The in vivo performance of this material was examined in the distal femur in New Zealand white rabbits. It was evaluated using micro CT and histologic analyses at time points of 6 and 12 weeks. These analyses of the defect sites verified normal healing response and new bone formation. The in vivo testing with rabbits showed good biocompatibility and excellent osteogenic ability.

A Novel Approach to Prepare Hydroxyapatite-Coated Biodegradable Polymer Microspheres Loaded with Magnetic Fe3O4 via Nanoparticle-Stabilized Emulsions

2012 ◽  
Vol 529-530 ◽  
pp. 223-228
Author(s):  
Masahiro Okada ◽  
Shoji Takeda ◽  
Tsutomu Furuzono
Keyword(s):  
Surface Modification ◽  
Biodegradable Polymer ◽  
Hydrophobic Surface ◽  
Volatile Oil ◽  
Polymer Microspheres ◽  
Oil Droplets ◽  
Novel Approach ◽  
Key Factor ◽  
Hap Nanoparticle

HAp-nanoparticle-coated biodegradable polymer microspheres loaded with magnetic Fe3O4 particles can be successfully prepared by evaporating volatile oil (dichloromethane) from HAp-nanoparticle-stabilized oil droplets containing biodegradable polymer and Fe3O4 particles without any molecular surfactants or polymeric stabilizers. In this study it was found that the hydrophobic surface modification for the Fe3O4 particles was a key factor to prepare stable HAp-nanoparticle-stabilized oil droplets (and HAp-nanoparticle-coated polymer microspheres) loaded with magnetic Fe3O4 particles.

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