A Novel Approach to Prepare Hydroxyapatite-Coated Biodegradable Polymer Microspheres Loaded with Magnetic Fe3O4 via Nanoparticle-Stabilized Emulsions

2012 ◽  
Vol 529-530 ◽  
pp. 223-228
Author(s):  
Masahiro Okada ◽  
Shoji Takeda ◽  
Tsutomu Furuzono

HAp-nanoparticle-coated biodegradable polymer microspheres loaded with magnetic Fe3O4 particles can be successfully prepared by evaporating volatile oil (dichloromethane) from HAp-nanoparticle-stabilized oil droplets containing biodegradable polymer and Fe3O4 particles without any molecular surfactants or polymeric stabilizers. In this study it was found that the hydrophobic surface modification for the Fe3O4 particles was a key factor to prepare stable HAp-nanoparticle-stabilized oil droplets (and HAp-nanoparticle-coated polymer microspheres) loaded with magnetic Fe3O4 particles.

2012 ◽  
Vol 290 (17) ◽  
pp. 1749-1757 ◽  
Author(s):  
Xueping Ge ◽  
Xuewu Ge ◽  
Mozhen Wang ◽  
Huarong Liu ◽  
Bin Fang ◽  
...  

2007 ◽  
Vol 280-283 ◽  
pp. 1805-1806
Author(s):  
Zhi Jun Cao ◽  
Jia Chen Liu ◽  
Li Bin Liu ◽  
Hao Ye ◽  
Yan Qiu Wei

A new approach was developed for surface modification of metallic surface. By treating nano-zirconia particles and metal surface in different charge state, nano-zirconia particles can be dispersedly inlaid in metal surface owing to electrostatic and nanometer effects. By using this method, metal components of complex shapes, especially those having inside surfaces, might be easily improved, i.e., enhanced surface hardness and wear rate.


AIChE Journal ◽  
2017 ◽  
Vol 63 (9) ◽  
pp. 4090-4102 ◽  
Author(s):  
Oluwasola Oribayo ◽  
Qinmin Pan ◽  
Xianshe Feng ◽  
Garry L. Rempel

2018 ◽  
Vol 433 ◽  
pp. 443-448 ◽  
Author(s):  
Vasilii Burtsev ◽  
Valentina Marchuk ◽  
Artem Kugaevskiy ◽  
Olga Guselnikova ◽  
Roman Elashnikov ◽  
...  

2020 ◽  
Vol 34 (06) ◽  
pp. 9892-9899
Author(s):  
Michael Katz ◽  
Shirin Sohrabi

The need for multiple plans has been established by various planning applications. In some, solution quality has the predominant role, while in others diversity is the key factor. Most recent work takes both plan quality and solution diversity into account under the generic umbrella of diverse planning. There is no common agreement, however, on a collection of computational problems that fall under that generic umbrella. This in particular might lead to a comparison between planners that have different solution guarantees or optimization criteria in mind. In this work we revisit diverse planning literature in search of such a collection of computational problems, classifying the existing planners to these problems. We formally define a taxonomy of computational problems with respect to both plan quality and solution diversity, extending the existing work. We propose a novel approach to diverse planning, exploiting existing classical planners via planning task reformulation and choosing a subset of plans of required size in post-processing. Based on that, we present planners for two computational problems, that most existing planners solve. Our experiments show that the proposed approach significantly improves over the best performing existing planners in terms of coverage, the overall solution quality, and the overall diversity according to various diversity metrics.


2019 ◽  
Vol 1 (2) ◽  
pp. 19-31
Author(s):  
Kalaivani S ◽  
Shalini Dhiman ◽  
Rajagopal T.K.P.

Emergency Department (ED) boarding –the inability to transfer emergency patients to inpatient beds- is a key factor contributing to ED overcrowding. This paper presents a novel approach to improving hospital operational efficiency and, therefore, to decreasing ED boarding. Using the historic data of 15,000 patients, admission results and patient information are correlated in order to identify important admission predictor factors. For example, the type of radiology exams prescribed by the ED physician is identified as among the most important predictors of admission. Based on these  factors, a  real-time prediction  model is  developed which  is able  to correctly predict  the  admission  result  of  four  out  of  every  five  ED  patients.  The  proposed admission  model  can  be  used  by inpatient  units  to  estimate  the  likelihood  of ED patients’ admission, and consequently, the number of incoming patients from ED in the near future. Using  similar prediction models,  hospitals can evaluate their short-time needs for inpatient care more accurately Emergency Department (ED) boarding – the inability to transfer emergency patients to inpatient beds- is a key factor contributing to ED overcrowding. This paper presents a novel approach to improving hospital operational efficiency and, therefore, to decreasing ED boarding. Using the historic data of 15,000 patients, admission results and patient information are correlated in order to identify important admission predictor factors. For example, the type of radiology exams prescribed by the ED physician is identified as among the most important predictors of admission. The proposed admission model can be used by inpatient units to estimate the likelihood of ED patients’ admission, and consequently, the number of incoming patients from ED in the near future. Using similar prediction models, hospitals can evaluate their short-time needs for inpatient care more accurately. We use three algorithms to build the predictive models: (1) logistic regression, (2) decision trees, and Analytic tools (accuracy=80.31%, AUC-ROC=0.859) than the decision tree accuracy=80.06%, AUC-ROC=0.824) and the logistic regression model (accuracy=79.94%, AUC-ROC=0.849). Drawing on logistic regression, we identify several factors related to hospital admissions including hospital site, age, arrival mode, triage category, care group, previous admission in the past month, and previous admission in the past year. From a different perspective, the research focuses on mobility data instead of personal data in general using Structural Equation Modelling analysis method. Based on this research finding, we identified an unexplored factor that can be used to predict the intention to disclose mobility data, and the result also confirmed that context aspects such as demographics and different personal data categories.


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