scholarly journals Montelukast improves pulmonary function measured by impulse oscillometry in children with asthma (Mio study)

2006 ◽  
Vol 100 (7) ◽  
pp. 1180-1185 ◽  
Author(s):  
Antonio Nieto ◽  
Rafael Pamies ◽  
Fernando Oliver ◽  
Alejandra Medina ◽  
Luis Caballero ◽  
...  
2019 ◽  
Vol 143 (2) ◽  
pp. AB12 ◽  
Author(s):  
Patricia P. Jorge ◽  
Jales Henrique Pereira Lima ◽  
Dirceu Sole ◽  
Gustavo F. Wandalsen

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Liang-Yuan Li ◽  
Tian-Sheng Yan ◽  
Jing Yang ◽  
Yu-Qi Li ◽  
Lin-Xi Fu ◽  
...  

Abstract Background Subjects with chronic respiratory symptoms and preserved pulmonary function (PPF) may have small airway dysfunction (SAD). As the most common means to detect SAD, spirometry needs good cooperation and its reliability is controversial. Impulse oscillometry (IOS) may complete the deficiency of spirometry and have higher sensitivity. We aimed to explore the diagnostic value of IOS to detect SAD in symptomatic subjects with PPF. Methods The evaluation of symptoms, spirometry and IOS results in 209 subjects with chronic respiratory symptoms and PPF were assessed. ROC curves of IOS to detect SAD were analyzed. Results 209 subjects with chronic respiratory symptoms and PPF were included. Subjects who reported sputum had higher R5–R20 and Fres than those who didn’t. Subjects with dyspnea had higher R5, R5–R20 and AX than those without. CAT and mMRC scores correlated better with IOS parameters than with spirometry. R5, R5–R20, AX and Fres in subjects with SAD (n = 42) significantly increased compared to those without. Cutoff values for IOS parameters to detect SAD were 0.30 kPa/L s for R5, 0.015 kPa/L s for R5–R20, 0.30 kPa/L for AX and 11.23 Hz for Fres. Fres has the largest AUC (0.665, P = 0.001) among these parameters. Compared with spirometry, prevalence of SAD was higher when measured with IOS. R5 could detect the most SAD subjects with a prevalence of 60.77% and a sensitivity of 81% (AUC = 0.659, P = 0.002). Conclusion IOS is more sensitive to detect SAD than spirometry in subjects with chronic respiratory symptoms and PPF, and it correlates better with symptoms. IOS could be an additional method for SAD detection in the early stage of diseases.


2008 ◽  
Vol 121 (2) ◽  
pp. S4-S4 ◽  
Author(s):  
T SONG ◽  
K KIM ◽  
M SOHN ◽  
K KIM ◽  
E KIM

2003 ◽  
Vol 16 (4) ◽  
pp. 305-317 ◽  
Author(s):  
Ana P. Martinez-Donate ◽  
Melbourne F. Hovell ◽  
Dennis R. Wahlgren ◽  
Susan B. Meltzer ◽  
Eli O. Meltzer ◽  
...  

2012 ◽  
Vol 24 (3) ◽  
pp. 472-489 ◽  
Author(s):  
Alison Crosbie

ObjectiveAsthma is a leading cause of chronic illness in children, impacting heavily on their daily life and participation in physical activity. The purpose of this systematic review was to investigate the evidence for the use of physical therapy to improve pulmonary function and aerobic capacity in children with asthma. Furthermore, the review aims to update previous literature on the effect of exercise on health related quality of life.MethodsA search was conducted for randomized control trials (RCTs) using the electronic databases Medline, Embase, SPORTDiscus, AMED, CINAHL, and The Cochrane Central Register of Controlled Trials. Studies were included if the participants were asthmatic children aged 6–18 years participating in any mode of physical exercise. Studies were reviewed for study quality, participant details, exercise intervention details, and intervention outcomes.ResultsA total of 16 studies and 516 subjects met inclusion criteria for review. Severity of asthma ranged from mild to severe. No improvement in pulmonary function was observed. Physical training led to an increase in aerobic capacity as measured by VO2max (mL/kg/min).ConclusionsFindings suggest that physical training does not improve pulmonary function in children with asthma, but does increase aerobic capacity. The small number of studies investigating quality of life suggests that physical training does improve health related quality of life; however further well designed randomized control trials are needed to verify these findings.


2020 ◽  
Vol 56 (1) ◽  
pp. 34-41
Author(s):  
Lara Farhat ◽  
Gabriele Vos ◽  
Aliva De ◽  
Diana S. Lee ◽  
Deepa Rastogi

2003 ◽  
Vol 64 (11) ◽  
pp. 1414-1420 ◽  
Author(s):  
Emmanuelle van Erck ◽  
Dominique M. Votion ◽  
Nathalie Kirschvink ◽  
Tatiana Art ◽  
Pierre Lekeux

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Ji Wu ◽  
Xi-Wen Yang ◽  
Ming Zhang

Objective. To systematically evaluate the efficacy of massage, a traditional treatment method of traditional Chinese medicine on children with asthma. Methods. Literatures from 5 databases using the date ranging from 1 January, 1990, to 13 December, 2016, were reviewed, which were all randomized controlled trials evaluating the efficacy on children with asthma and effect on lung function mainly by massage therapy. Results. 14 researches with 1299 patients were included in the meta-analysis. Compared with control group, a better efficacy was found in treatment group, which focused on massage therapy. Compared with control group, there was remarkable increase on FEV1 as well as PEF in treatment group. Conclusion. All studies have shown that massage therapy has a significantly positive effect on children with asthma, improves the pulmonary function parameters of large airway, reduces the plasma concentrations of PAF and prostaglandin, and increases the levels of PAF-AH and DP1; therefore, it greatly improves pulmonary function. However, the limited research designs of included studies lead to high risk of bias. More randomized controlled trials with better methodological quality are needed to further confirm the effectiveness of massage.


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