Association between TBXA2R T924C polymorphism and pulmonary function in Korean children with asthma*1

ObjectiveAsthma is a leading cause of chronic illness in children, impacting heavily on their daily life and participation in physical activity. The purpose of this systematic review was to investigate the evidence for the use of physical therapy to improve pulmonary function and aerobic capacity in children with asthma. Furthermore, the review aims to update previous literature on the effect of exercise on health related quality of life.MethodsA search was conducted for randomized control trials (RCTs) using the electronic databases Medline, Embase, SPORTDiscus, AMED, CINAHL, and The Cochrane Central Register of Controlled Trials. Studies were included if the participants were asthmatic children aged 6–18 years participating in any mode of physical exercise. Studies were reviewed for study quality, participant details, exercise intervention details, and intervention outcomes.ResultsA total of 16 studies and 516 subjects met inclusion criteria for review. Severity of asthma ranged from mild to severe. No improvement in pulmonary function was observed. Physical training led to an increase in aerobic capacity as measured by VO2max (mL/kg/min).ConclusionsFindings suggest that physical training does not improve pulmonary function in children with asthma, but does increase aerobic capacity. The small number of studies investigating quality of life suggests that physical training does improve health related quality of life; however further well designed randomized control trials are needed to verify these findings.

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Atopy and pulmonary function among healthy‐weight and overweight/obese children with asthma

Pediatric Pulmonology ◽

10.1002/ppul.25005 ◽

2020 ◽

Vol 56 (1) ◽

pp. 34-41

Author(s):

Lara Farhat ◽

Gabriele Vos ◽

Aliva De ◽

Diana S. Lee ◽

Deepa Rastogi

Keyword(s):

Pulmonary Function ◽

Healthy Weight ◽

Obese Children ◽

Children With Asthma

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Massage Therapy in Children with Asthma: A Systematic Review and Meta-Analysis

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2017/5620568 ◽

2017 ◽

Vol 2017 ◽

pp. 1-8 ◽

Cited By ~ 5

Author(s):

Ji Wu ◽

Xi-Wen Yang ◽

Ming Zhang

Keyword(s):

Treatment Group ◽

Pulmonary Function ◽

Randomized Controlled Trials ◽

Meta Analysis ◽

Plasma Concentrations ◽

Massage Therapy ◽

Control Group ◽

Controlled Trials ◽

Randomized Controlled ◽

Children With Asthma

Objective. To systematically evaluate the efficacy of massage, a traditional treatment method of traditional Chinese medicine on children with asthma. Methods. Literatures from 5 databases using the date ranging from 1 January, 1990, to 13 December, 2016, were reviewed, which were all randomized controlled trials evaluating the efficacy on children with asthma and effect on lung function mainly by massage therapy. Results. 14 researches with 1299 patients were included in the meta-analysis. Compared with control group, a better efficacy was found in treatment group, which focused on massage therapy. Compared with control group, there was remarkable increase on FEV1 as well as PEF in treatment group. Conclusion. All studies have shown that massage therapy has a significantly positive effect on children with asthma, improves the pulmonary function parameters of large airway, reduces the plasma concentrations of PAF and prostaglandin, and increases the levels of PAF-AH and DP1; therefore, it greatly improves pulmonary function. However, the limited research designs of included studies lead to high risk of bias. More randomized controlled trials with better methodological quality are needed to further confirm the effectiveness of massage.

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