Prevalence of obstructive lung disease in HIV population: A cross sectional study

Abstract Background Individuals experiencing homelessness are at an increased risk of respiratory illness due to high prevalence of underlying chronic conditions, inadequate ventilation and crowding in shelters, and difficulty accessing health services. Few studies have investigated the prevalence and transmission of viral respiratory infections within shelters. We sought to determine the prevalence and risk factors for influenza-like illness (ILI) at two homeless shelters in Seattle, WA. Methods Between January and April 2019, we conducted a cross-sectional study of adults experiencing homelessness who identified their primary residence as one of the two shelters in Seattle. Participants voluntarily enrolled if they self-reported at least two symptoms of acute respiratory illness in the past week. Demographic, clinical, and behavioral data were ascertained via questionnaire, and a mid-nasal swab was collected. ILI was defined as fever with cough or sore throat. Chronic lung disease was defined as chronic obstructive pulmonary disease, asthma, and/or chronic bronchitis. Results Among the 480 participants enrolled in the study, 204 (42.5%) reported ILI symptoms. Of those enrolled, 144 (30.0%) had chronic lung disease. The prevalence of ILI was higher among individuals with chronic lung disease (53.5% vs. 42.5%, P = 0.001). A total of 422 (87.9%) had health insurance; the prevalence of ILI was lower among those with health insurance (42.4% vs. 57.8%, P = 0.66). 216 (45.0%) of participants received flu vaccine; the prevalence of ILI was similar among those who received the vaccine than those that did not (42.6% vs. 42.4%, P = 1.00). 129 (30.6%) of those with health insurance sought care for their reported symptoms; ILI was more prevalent in those that sought care than those that did not throughout the observation period (33.8% vs. 21.7%, P = 0.002). Of those with ILI that sought care, 46 (54.8%, P = 0.42) received antivirals or antibiotics. Laboratory results for the corresponding mid-nasal swabs are pending. Conclusion A large proportion of our study population self-reported ILI and chronic lung disease. Despite high insurance coverage, a low proportion of homeless enrolled sought care for their symptoms or received treatment. Disclosures All authors: No reported disclosures.

Download Full-text

Noncommunicable Lung Disease in Sub-Saharan Africa. A Community-based Cross-Sectional Study of Adults in Urban Malawi

American Journal of Respiratory and Critical Care Medicine ◽

10.1164/rccm.201509-1807oc ◽

2016 ◽

Vol 194 (1) ◽

pp. 67-76 ◽

Cited By ~ 41

Author(s):

Jamilah Meghji ◽

Gilbert Nadeau ◽

Kourtney J. Davis ◽

Duolao Wang ◽

Moffat J. Nyirenda ◽

...

Keyword(s):

Lung Disease ◽

Cross Sectional Study ◽

Sub Saharan Africa ◽

Sectional Study ◽

Community Based ◽

Cross Sectional ◽

Sub Saharan

Download Full-text

A low prevalence of rapidly progressive interstitial lung disease in Latin American patients with dermatomyositis: A multicenter cross-sectional study

10.47660/cbr.2020.17022 ◽

2021 ◽

Author(s):

Pablo Arturo Olivo Pallo ◽

Leonardo Santos Hoff ◽

Samuel Katsuyuki Shinjo ◽

Jiram Torres ◽

Amelia Granel

Keyword(s):

Interstitial Lung Disease ◽

Lung Disease ◽

Latin American ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Low Prevalence

Download Full-text

A Comparative Study of the Sarcopenia Screening in Older Patients with Interstitial Lung Disease

10.21203/rs.3.rs-936545/v1 ◽

2021 ◽

Author(s):

Masatoshi Hanada ◽

Noriho Sakamoto ◽

Hiroshi Ishimoto ◽

Takashi Kido ◽

Takuto Miyamura ◽

...

Keyword(s):

Interstitial Lung Disease ◽

Lung Disease ◽

Operating Characteristic ◽

Cross Sectional Study ◽

Screening Tools ◽

Calf Circumference ◽

Sectional Study ◽

Cross Sectional ◽

Receiver Operating Characteristic Curves ◽

Climbing Stairs

Abstract Background: The calf circumference (CalF), the strength, assistance in walking, rising from a chair, climbing stairs, and falls (SARC-F) and the SARC-CalF questionnaires for sarcopenia screening have been used by Asian Working Group for Sarcopenia 2019 (AWGS 2019). The aim of this study was to assess accuracy of these three sarcopenia screening tools in patients with interstitial lung disease. Methods: In this cross-sectional study, stable patients with interstitial lung disease were enrolled. The SARC-F, SARC-CalF, and CalF, used in patients with interstitial lung disease, were compared to the diagnostic criteria proposed by AWGS 2019. The accuracy of screening tools was compared using sensitivity and specificity. Moreover, areas under the receiver operating characteristic curves (AUC) were computed. Results: Seventy eight patients were analyzed, and sarcopenia was identified in 25 (32.1%) patients with interstitial lung disease by the AWGS 2019 criteria. The sensitivity of the CalF was highest (96%) of the three screening tools, while the specificity was 60%. The sensitivity of SARC-F and SARC-CalF were 24% and 68%, while the specificity were 92% and 66%, respectively. The AUCs of CalF, SARC-F, and SARC-CalF in all patients were 0.78, 0.58, and 0.67, respectively. Conclusions: The CalF is most suitable for screening sarcopenia in patients with interstitial lung disease, while SARC-F and SARC-CalF are not.

Download Full-text

Lung involvement prevalence in patients with early rheumatoid arthritis without known pulmonary disease: a multicentric cross sectional study

Advances in Rheumatology ◽

10.1186/s42358-021-00209-0 ◽

2021 ◽

Vol 61 (1) ◽

Author(s):

Francisco Paulin ◽

Anastasia Secco ◽

Federico Benavidez ◽

Juan José Rodríguez Moncalvo ◽

Orlando Gabriel Carballo ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Lung Disease ◽

Cross Sectional Study ◽

Joint Disease ◽

Joint Involvement ◽

Lung Involvement ◽

Functional Tests ◽

Sectional Study ◽

Cross Sectional ◽

Early Ra

Abstract Background Clinically evident interstitial lung disease (ILD) affects between 10 and 42% of the patients with rheumatoid arthritis (RA). Airway involvement seems to be even more common. Most of the available evidence comes from studies performed in established RA patients. The aim of our study was to know the prevalence of non-diagnosed lung disease (airway and interstitial involvement) in patients with early RA and look for associated factors. Methods We designed an observational, multicenter, cross-sectional study, and included patients with RA of less than two years since diagnosis. We performed a structured questionnaire, HRCT and lung functional tests looking for lung disease, together with joint disease evaluation. We analyzed which variables were associated with the presence of lung disease on HRCT. Results We included 83 patients, 83% females. The median (IQR) of time since RA diagnosis was 3 (1–6) months. In the HRCT, 57 patients had airway compromisea (72%), and 6 had interstitial abnormalities (7.5%). The most common altertion found in lung functional tests was a reduced DLCO (14%). The presence of at least one abnormality in the physical exam was associated with lung involvement on HRCT [13 (21.6%) vs 0 (0%); p = 0.026]. Also, patients with lung involvement presented significantly lower values of FVC% and DLCO%, and higher values of RV/TLC. No variable related to joint involvement was found associated with alterations in HRCT. Conclusion Our study shows that a large proportion of early RA patients has abnormal findings in HRCT. Further studies are required to confirm these findings.

Download Full-text