Synthesis, spectroscopic characterization, crystal structure, DNA interaction study and in vitro biological screenings of 4-(5-chloro-2-hydroxyphenylamino)-4-oxobut-2-enoic acid

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Muhammad Sirajuddin ◽  
Nooruddin ◽  
Saqib Ali ◽  
Vickie McKee ◽  
Shahan Zeb Khan ◽  
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Crystal Structure ◽  
Spectroscopic Characterization ◽  
Dna Interaction ◽  
Enoic Acid ◽  
Interaction Study

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Muhammad Altaf ◽  
Adam A. Seliman ◽  
Shipra Yadav ◽  
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Dna Interaction ◽  
In Vitro Cytotoxicity ◽  
Interaction Study

Synthesis, crystal structure, DNA interaction and in vitro anticancer activity of a Cu(ii) complex of purpurin: dual poison for human DNA topoisomerase I and II

RSC Advances ◽  
2014 ◽  
Vol 4 (103) ◽  
pp. 59344-59357 ◽  
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Chetan Kumar Jain ◽  
Sanjoy K. Dey ◽  
Rajat Saha ◽  
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Crystal Structure ◽  
Topoisomerase I ◽  
Dna Interaction ◽  
Dna Topoisomerase I ◽  
Oxygen Species ◽  
Dna Topoisomerase ◽  
Human Dna ◽  
Anti Tumor Activity ◽  
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Although generation of reactive oxygen species (ROS) by anthracycline anticancer drugs is essential for anti-tumor activity, they make these drugs cardiotoxic.

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Polyhedron ◽  
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Vol 179 ◽  
pp. 114369 ◽  
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Sen Li ◽  
Jin'an Zhao ◽  
Bangpeng Yuan ◽  
Xinyang Wang ◽  
Junshuai Zhang ◽  
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Keyword(s):  
Crystal Structure ◽  
Anticancer Activity ◽  
Dna Interaction ◽  
Quinoline Derivative
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