scholarly journals Nigella sativa seed oil suppresses cell proliferation and induces ROS dependent mitochondrial apoptosis through p53 pathway in hepatocellular carcinoma cells

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pp. 70-78 ◽  
Author(s):  
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Vol 88 ◽  
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Vol 466 (1) ◽  
pp. 115-121 ◽  
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Hyun Kook Cho ◽  
So Young Kim ◽  
Yi Yi Kyaw ◽  
Aye Aye Win ◽  
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HBx protein is encoded by HBV and plays a critical role in hepatocarcinogenesis. In the present study we show that HBx activates the expression of the CREBH transcription factor and interacts with the activated CREBH. CREBH activation by HBx may result in cell proliferation.


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