Cognitive deficits in first-episode psychosis: A population-based study in São Paulo, Brazil

OBJECTIVE: To translate and adapt the Brazilian version of the Camberwell Assessment of Needs schedule for research, and to assess its inter-rater reliability in a sample of first-episode psychosis cases in São Paulo, Brazil. METHOD: A sub-sample of participants included in a study of first-episode psychosis in São Paulo was assessed utilizing the 22 domains of the Brazilian version of the Camberwell Assessment of Needs. The Camberwell Assessment of Needs was applied, tape-recorded and rated by research assistants. An independent rater gave scores to the same participants, based on the recorded interviews. The kappa coefficient and the intraclass correlation coefficient were used to assess inter-rater reliability. RESULTS: Fifty-two subjects were included. For seven domains the inter-rater reliability was almost perfect to total (range: 0.81 to 1.0). The domains with the lowest agreement were transport and benefits. The inter-rater reliability for the total number of needs was excellent (ICC = 0.95). CONCLUSIONS: The inter-rater reliability of the Camberwell Assessment of Needs was similar to what has been found in previous studies. The Camberwell Assessment of Needs showed to be easy to use and reliable with first-episode psychosis individuals. The use of standardized instruments to assess needs of care in Brazil will contribute to the assessment of the effectiveness of treatment and to the planning of individualized care for individuals with mental illnesses.

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Prevalence of N-Methyl-d-Aspartate Receptor antibody (NMDAR-Ab) encephalitis in patients with first episode psychosis and treatment resistant schizophrenia on clozapine, a population based study

Schizophrenia Research ◽

10.1016/j.schres.2019.11.023 ◽

2020 ◽

Vol 222 ◽

pp. 455-461

Author(s):

Eric Kelleher ◽

Patricia McNamara ◽

Jean Dunne ◽

Brian Fitzmaurice ◽

Elizabeth A. Heron ◽

...

Keyword(s):

Population Based ◽

First Episode Psychosis ◽

First Episode ◽

Treatment Resistant ◽

Population Based Study ◽

Receptor Antibody ◽

Aspartate Receptor ◽

Episode Psychosis

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Cardiovascular risk factors in patients with first-episode psychosis in São Paulo, Brazil

General Hospital Psychiatry ◽

10.1016/j.genhosppsych.2011.12.010 ◽

2012 ◽

Vol 34 (3) ◽

pp. 268-275 ◽

Cited By ~ 12

Author(s):

Isabela M. Benseñor ◽

André R. Brunoni ◽

Luis Augusto Pilan ◽

Alessandra C. Goulart ◽

Geraldo F. Busatto ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

First Episode Psychosis ◽

Sao Paulo ◽

First Episode ◽

São Paulo ◽

Episode Psychosis

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Incidence of first-contact psychosis in São Paulo, Brazil

The British Journal of Psychiatry ◽

10.1192/bjp.191.51.s102 ◽

2007 ◽

Vol 191 (S51) ◽

pp. s102-s106 ◽

Cited By ~ 47

Author(s):

Paulo R. Menezes ◽

Marcia Scazufca ◽

Geraldo F. Busatto ◽

Letícia M. S. Coutinho ◽

Philip K. Mcguire ◽

...

Keyword(s):

At Risk ◽

Census Data ◽

First Episode Psychosis ◽

Sao Paulo ◽

First Episode ◽

São Paulo ◽

Middle Income ◽

Middle Income Countries ◽

Episode Psychosis ◽

First Contact

BackgroundLittle is known about the incidence of first-episode psychosis in urban centres of low- or middle-income countriesAimsTo estimate the incidence of psychosis in São Paulo, a large metropolis of BrazilMethodProspective survey of first-episode psychosis among residents aged 18–64 years resident in a defined area of São Paulo, over a 30-month period (July 2002- December 2004). Assessments were carried out with the SCID–I, and diagnoses given according to DSM – IV criteria. Population at risk was drawn from the 2000 Census dataResultsThere were 367 first-episode cases identified (51% women), and almost 40% fulfilled criteria for schizophrenia or schizophreniform disorder. The incidence rate for any psychosis was 15.8/100 000 person-years at risk (95% CI 14.3–17.6). Incidence of non-affective psychoses was higher among younger malesConclusionsIncidence of psychosis in São Paulo was lower than expected for a large metropolis

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Cognitive performance is related to cortical grey matter volumes in early stages of schizophrenia: A population-based study of first-episode psychosis

Schizophrenia Research ◽

10.1016/j.schres.2009.06.020 ◽

2009 ◽

Vol 113 (2-3) ◽

pp. 200-209 ◽

Cited By ~ 29

Author(s):

Taís M. Minatogawa-Chang ◽

Maristela S. Schaufelberger ◽

Adriana M. Ayres ◽

Fábio L.S. Duran ◽

Elisa K. Gutt ◽

...

Keyword(s):

Cognitive Performance ◽

Grey Matter ◽

Population Based ◽

First Episode Psychosis ◽

First Episode ◽

Population Based Study ◽

Early Stages ◽

Episode Psychosis ◽

Cortical Grey Matter

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Estimating the incidence of first-episode psychosis using population-based health administrative data to inform early psychosis intervention services

Psychological Medicine ◽

10.1017/s0033291718002933 ◽

2018 ◽

Vol 49 (12) ◽

pp. 2091-2099 ◽

Cited By ~ 8

Author(s):

Kelly K. Anderson ◽

Ross Norman ◽

Arlene G. MacDougall ◽

Jordan Edwards ◽

Lena Palaniyappan ◽

...

Keyword(s):

Psychotic Disorder ◽

Administrative Data ◽

Catchment Area ◽

Population Based ◽

First Episode Psychosis ◽

Case Definition ◽

First Episode ◽

Affective Psychosis ◽

Health Administrative Data ◽

Episode Psychosis

AbstractBackgroundDiscrepancies between population-based estimates of the incidence of psychotic disorder and the treated incidence reported by early psychosis intervention (EPI) programs suggest additional cases may be receiving services elsewhere in the health system. Our objective was to estimate the incidence of non-affective psychotic disorder in the catchment area of an EPI program, and compare this to EPI-treated incidence estimates.MethodsWe constructed a retrospective cohort (1997–2015) of incident cases of non-affective psychosis aged 16–50 years in an EPI program catchment using population-based linked health administrative data. Cases were identified by either one hospitalization or two outpatient physician billings within a 12-month period with a diagnosis of non-affective psychosis. We estimated the cumulative incidence and EPI-treated incidence of non-affective psychosis using denominator data from the census. We also estimated the incidence of first-episode psychosis (people who would meet the case definition for an EPI program) using a novel approach.ResultsOur case definition identified 3245 cases of incident non-affective psychosis over the 17-year period. We estimate that the incidence of first-episode non-affective psychosis in the program catchment area is 33.3 per 100 000 per year (95% CI 31.4–35.1), which is more than twice as high as the EPI-treated incidence of 18.8 per 100 000 per year (95% CI 17.4–20.3).ConclusionsCase ascertainment strategies limited to specialized psychiatric services may substantially underestimate the incidence of non-affective psychotic disorders, relative to population-based estimates. Accurate information on the epidemiology of first-episode psychosis will enable us to more effectively resource EPI services and evaluate their coverage.

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