Prenatal exposure to air pollutants and childhood atopic dermatitis and allergic rhinitis adopting machine learning approaches: 14-year follow-up birth cohort study

2021 ◽  
pp. 145982
Author(s):  
Yu Huang ◽  
Hui-Ju Wen ◽  
Yue Leon Guo ◽  
Tzu-Yin Wei ◽  
Wei-Cheng Wang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Cohort Study ◽  
Birth Cohort ◽  
Prenatal Exposure ◽  
Air Pollutants ◽  
Birth Cohort Study ◽  
Learning Approaches

scholarly journals Prenatal exposure to arsenic and lung function in children from the New Hampshire Birth Cohort Study

2021 ◽  
Vol 155 ◽  
pp. 106673
Author(s):  
Antonio J. Signes-Pastor ◽  
Pablo Martinez-Camblor ◽  
Emily Baker ◽  
Juliette Madan ◽  
Margaret F. Guill ◽  
...  
Keyword(s):  
Cohort Study ◽  
Lung Function ◽  
Birth Cohort ◽  
New Hampshire ◽  
Prenatal Exposure ◽  
Birth Cohort Study

The Study of Asian Women and their Offspring’s Development and Environmental Exposures (SAWASDEE): A northern Thailand birth cohort study (Preprint)

2021 ◽  
Author(s):  
Dana Barr ◽  
Nancy Fiedler ◽  
Tippawan Prapamontol ◽  
Panrapee Suttiwan ◽  
Warangkana Naksen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Prenatal Exposure ◽  
Environmental Exposures ◽  
World Health ◽  
Birth Cohort Study ◽  
Asian Women ◽  
Northern Thailand ◽  
Prospective Longitudinal ◽  
The Impact

BACKGROUND Prenatal exposure to pesticides have been linked to adverse neurodevelopmental outcomes. Gaps exist in the current literature about the timing and magnitude of exposures that result in these adverse outcomes. OBJECTIVE The Study of Asian Women and their Offspring’s Development and Environmental Exposures (SAWASDEE) Cohort was established to investigate the impact of prenatal exposure to pesticides on neurodevelopment during infancy and early childhood in northern Thailand. METHODS Recruitment of this prospective, longitudinal birth cohort began in July 2017 and was completed in June 2019 in Chom Thong and Fang, two farming districts in Chiang Mai Province in northern Thailand. Follow up of the study participants is on-going. During pregnancy, seven questionnaires were administered. Time-resolved biospecimen samples were collected monthly (for urine) and during each trimester (for blood) at antenatal care visits. Medical records were abstracted. Infants were administered the NICU Network Neurobehavioral Scale (NNNS) test at one month of age. We will complete a number of additional exposure related analyses. RESULTS A total of 1298 women were screened and of those 394 women were enrolled. The mean gestational age at enrollment was 9.9 weeks (STD = 2.6). Differences in literacy were observed between Chom Thong and Fang participants. In Fang about 51% reported being able to read in Thai compared to about 95% in Chom Thong. The percentages were comparable for reporting to be able to write in Thai. A total of 322 mother-child pairs completed the NNNS. CONCLUSIONS This longitudinal birth cohort study will inform risk assessment standards for pregnant women in Thailand and other countries. Building awareness of how insecticide exposure during specific windows of pregnancy affects the neurodevelopmental trajectories of children in developing countries is a specific need recognized by the World Health Organization.

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