The Study of Asian Women and their Offspring’s Development and Environmental Exposures (SAWASDEE): A northern Thailand birth cohort study (Preprint)

2021 ◽  
Author(s):  
Dana Barr ◽  
Nancy Fiedler ◽  
Tippawan Prapamontol ◽  
Panrapee Suttiwan ◽  
Warangkana Naksen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Prenatal Exposure ◽  
Environmental Exposures ◽  
World Health ◽  
Birth Cohort Study ◽  
Asian Women ◽  
Northern Thailand ◽  
Prospective Longitudinal ◽  
The Impact

BACKGROUND Prenatal exposure to pesticides have been linked to adverse neurodevelopmental outcomes. Gaps exist in the current literature about the timing and magnitude of exposures that result in these adverse outcomes. OBJECTIVE The Study of Asian Women and their Offspring’s Development and Environmental Exposures (SAWASDEE) Cohort was established to investigate the impact of prenatal exposure to pesticides on neurodevelopment during infancy and early childhood in northern Thailand. METHODS Recruitment of this prospective, longitudinal birth cohort began in July 2017 and was completed in June 2019 in Chom Thong and Fang, two farming districts in Chiang Mai Province in northern Thailand. Follow up of the study participants is on-going. During pregnancy, seven questionnaires were administered. Time-resolved biospecimen samples were collected monthly (for urine) and during each trimester (for blood) at antenatal care visits. Medical records were abstracted. Infants were administered the NICU Network Neurobehavioral Scale (NNNS) test at one month of age. We will complete a number of additional exposure related analyses. RESULTS A total of 1298 women were screened and of those 394 women were enrolled. The mean gestational age at enrollment was 9.9 weeks (STD = 2.6). Differences in literacy were observed between Chom Thong and Fang participants. In Fang about 51% reported being able to read in Thai compared to about 95% in Chom Thong. The percentages were comparable for reporting to be able to write in Thai. A total of 322 mother-child pairs completed the NNNS. CONCLUSIONS This longitudinal birth cohort study will inform risk assessment standards for pregnant women in Thailand and other countries. Building awareness of how insecticide exposure during specific windows of pregnancy affects the neurodevelopmental trajectories of children in developing countries is a specific need recognized by the World Health Organization.

scholarly journals Prenatal exposure to arsenic and lung function in children from the New Hampshire Birth Cohort Study

2021 ◽  
Vol 155 ◽  
pp. 106673
Author(s):  
Antonio J. Signes-Pastor ◽  
Pablo Martinez-Camblor ◽  
Emily Baker ◽  
Juliette Madan ◽  
Margaret F. Guill ◽  
...  
Keyword(s):  
Cohort Study ◽  
Lung Function ◽  
Birth Cohort ◽  
New Hampshire ◽  
Prenatal Exposure ◽  
Birth Cohort Study

scholarly journals Impact of Cleft lip and Palate on Mother-to-Infant Bonding: a Cross-Sectional Study in the Japan Environment and Children's Study

2019 ◽  
Author(s):  
Shinobu Tsuchiya ◽  
Masahiro Tsuchiya ◽  
Haruki Momma ◽  
Takeyoshi Koseki ◽  
Kaoru Igarashi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Maternal Depression ◽  
Birth Cohort ◽  
Maternal Age ◽  
Cleft Lip ◽  
Advanced Age ◽  
Psychological Status ◽  
Birth Cohort Study ◽  
Increased Risk ◽  
The Impact

Abstract Background Cleft lip and/or palate (CL/P) is among the most prevalent congenital birth defects. They negatively affect maternal psychological status and may consequently result in higher prevalence of child maltreatment. However, the association of CL/P births with bonding disorders still remains unclear. To address this question, we examined the impact of CL/P birth on mother-to-infant bonding, using the nationwide birth cohort study, Japan Environment and Children's Study. Methods This study was conducted as a nationwide birth cohort study of the Japan environment and children’s study (JECS), an ongoing nationwide birth cohort study in Japan. 104,065 of foetuses in fifteen regional centres in JECS were enrolled. Finally, the participants consisted of 79,140 mother-infant pairs, of which 211 mothers with CL/P infants were included in our analyses. Results First, no increased risk of bonding disorders was observed among all the mothers with CL/P births (odds ratio [95% CI]; 0.97 [0.63-1.48], p = 0.880), and advanced maternal age or multiple parity would adversely affect the associations between bonding disorders and CL/P births, respectively. Thus, after stratification with a combination of maternal age and parity, a significant association of CL/P birth with bonding disorders was found only among advanced-age multiparae (OR [95% CI] = 2.51 [1.17-5.37], p = 0.018), but it was weakened after additional adjustment for maternal depression. Conclusion CL/P birth may increase the risk of bonding disorders among advanced-age multiparae possibly through maternal depression. This finding provides valuable information for the provision of multidisciplinary cleft care.

scholarly journals Diagnosis of overweight and obesity in adolescents from the 1993 Pelotas Birth Cohort Study, Rio Grande do Sul State, Brazil: comparison of two diagnostic criteria

2007 ◽  
Vol 23 (12) ◽  
pp. 2993-2999 ◽  
Author(s):  
Maria de Fátima Alves Vieira ◽  
Cora Luiza Pavin Araújo ◽  
Marilda Borges Neutzling ◽  
Pedro Curi Hallal ◽  
Ana Maria Baptista Menezes
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Task Force ◽  
High Specificity ◽  
Total Sample ◽  
Overweight And Obesity ◽  
World Health ◽  
Birth Cohort Study ◽  
Original Cohort ◽  
Prevalence Of Obesity

Various cut-off points for body mass index have been proposed to assess nutritional status in adolescents. The aim of this study was to compare two methods for evaluating overweight and obesity. In 2004-5, 4,452 adolescents from the 1993 Pelotas (Brazil) birth cohort study were evaluated, representing 87.5% of the original cohort. Overweight and obesity were evaluated using the methods proposed by the World Health Organization (WHO) and International Obesity Task Force (IOTF). Prevalence of overweight was similar when comparing the two methods (WHO: 23.2%; IOTF: 21.6%). Prevalence of obesity was higher according to the WHO criterion (total sample: 11.6%; boys: 15.1%; girls: 8.2%) as compared to IOTF (total sample: 5.0%; boys: 5.6%; girls: 4.4%). The kappa statistic was around 0.9 for determining overweight and 0.4 for obesity. The IOTF classification showed high specificity in comparison to the WHO criterion for determining overweight and obesity. However, sensitivity was high for overweight but low for obesity. Our data show that the IOTF classification underestimates the prevalence of obesity in early adolescence.

Prenatal exposure to residential PM2.5 and anogenital distance in infants at birth: A birth cohort study from Shanghai, China

2020 ◽  
Vol 264 ◽  
pp. 114684
Author(s):  
Xiaowei Sun ◽  
Cong Liu ◽  
Ziliang Wang ◽  
Fen Yang ◽  
Hong Liang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Prenatal Exposure ◽  
Birth Cohort Study ◽  
Anogenital Distance

scholarly journals Prenatal Exposure to Phthalates and Newborn Telomere Length: A Birth Cohort Study in Wuhan, China

2019 ◽  
Vol 127 (8) ◽  
pp. 087007 ◽  
Author(s):  
Lulu Song ◽  
Bingqing Liu ◽  
Mingyang Wu ◽  
Lina Zhang ◽  
Lulin Wang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Telomere Length ◽  
Birth Cohort ◽  
Prenatal Exposure ◽  
Birth Cohort Study
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