scholarly journals Management of the noxious weed; Medicago polymorpha L. via allelopathy of some medicinal plants from Taif region, Saudi Arabia

2018 ◽  
Vol 25 (7) ◽  
pp. 1339-1347 ◽  
Author(s):  
Mardi Mohammed Algandaby ◽  
Salama M. El-Darier
Author(s):  
Fahd A. Nasr ◽  
Nael Abutaha ◽  
Mohammad Al-Zahrani ◽  
Muhammad Farooq ◽  
Mohammad A Wadaan

Background: Medicinal plants have been used in traditional medicine for the treatment of numerous diseases worldwide. There is a dire need for new anticancer agents and plants used in traditional medicine are a particularly useful source. Materials and methods: In this study, extracts of five different plants that grow in the desert of Saudi Arabia were evaluated to assess their cytotoxicity against the MDA-MB-231 breast cancer cell line. Soxhlet extraction was carried out on the leaves and stems using different solvents. The cytotoxicity of these extracts against MDA-MB-231 breast cancer cells was assessed using the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) and lactate dehydrogenase (LDH) assays. The apoptotic cellular morphological changes were observed using inverted and fluorescence microscopes. Results: Our results showed that two of the five different medicinal plants (Rumex vesicarius and Malva parviflora) exhibited strong anticancer activity against the breast cancer cells. Specifically, 2 of the 40 extracts (from the five studied plants) showed promising activity. The chloroform extract of the stem of R. vesicarius (RSV CHCL3) exhibited moderate anticancer activity with a half-maximal inhibitory concentration (IC50) of 230 µg/mL while that of the hexane extract of M. parviflora stems (MPS Hex) was 248 µg/mL. Loss of cell integrity, shrinkage of the cytoplasm, and cell detachment were observed in the extract-treated MDA-MB-231 cells. Conclusion: R. vesicarius and M. parviflora chloroform and n-hexane stem extracts showed significant cytotoxicity against MDA-MB-231 human breast carcinoma cells.


2020 ◽  
Vol 257 ◽  
pp. 112899 ◽  
Author(s):  
Afnan Alqethami ◽  
Amal Y. Aldhebiani ◽  
Irene Teixidor-Toneu

Molecules ◽  
2012 ◽  
Vol 17 (10) ◽  
pp. 11379-11390 ◽  
Author(s):  
Nawal M. Al-Musayeib ◽  
Ramzi A. Mothana ◽  
Shaza Al-Massarani ◽  
An Matheeussen ◽  
Paul Cos ◽  
...  

2020 ◽  
Vol 27 (10) ◽  
pp. 2706-2718 ◽  
Author(s):  
Riaz Ullah ◽  
Ali S. Alqahtani ◽  
Omar M.A. Noman ◽  
Abdulaziz M. Alqahtani ◽  
Samir Ibenmoussa ◽  
...  

Author(s):  
Abdulrahman Ali Alzandi ◽  
Essam Ahmed Taher ◽  
Nageeb A. Al-Sagheer ◽  
Abdul Wali Al-Khulaidi ◽  
Mohamed Azizi ◽  
...  

2021 ◽  
Vol 11 (16) ◽  
pp. 7620
Author(s):  
Sameer H. Qari ◽  
Abdulmajeed F. Alrefaei ◽  
Wessam Filfilan ◽  
Alaa Qumsani

Understanding the natural resources of native flora in a particular area is essential to be able to identify, record, and update existing records concerning the flora of that area, especially medicinal plants. Until recently, there has been very little scientific documentation on the biological diversity of Aljumum flora. The current study aimed to document medicinal plants among the flora of this region and determine the traditional usages that are documented in the literature. In the flowering season from November 2019 to May 2020, we conducted more than 80 field trips to the study area. The results reported 90 species belonging to 79 genera and 34 families in the Aljumum region, which constitute 82 species of medicinal plants from a total of 2253 known species in Saudi Arabia. The most distributed species were Calotropis procera, Panicum turgidum, and Aerva javanica (5.31%); within four endemic families, we found Fabaceae (32.35%), Poaceae (20.58%), and Asteraceae and Brassicaceae (17.64%). The present study reviews a collection of medicinal plants in Aljumum used in ethnomedicine. Additionally, these natural resources should be preserved, and therefore, conservation programs should be established to protect the natural diversity of the plant species in this region with sustainable environmental management.


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