Ultra-sensitive nucleic acid detection based on target cycling of triple helix molecular switch and ATRP double signal amplification

2021 ◽  
Vol 337 ◽  
pp. 129791
Author(s):  
Haobo Sun ◽  
Lisheng Qian ◽  
Jinming Kong ◽  
Xueji Zhang
Keyword(s):  
Nucleic Acid ◽  
Signal Amplification ◽  
Triple Helix ◽  
Molecular Switch ◽  
Nucleic Acid Detection

A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

2014 ◽  
Vol 50 (66) ◽  
pp. 9409-9412 ◽  
Author(s):  
Sujuan Ye ◽  
Yanying Wu ◽  
Wen Zhang ◽  
Na Li ◽  
Bo Tang
Keyword(s):  
Nucleic Acids ◽  
Signal Amplification ◽  
Triple Helix ◽  
Detection System ◽  
Molecular Switch ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Multiple Cycle ◽  
Enhanced Raman Scattering

A sensitive surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification.

Strategies for Signal Amplification in Nucleic Acid Detection

2001 ◽  
Vol 19 (1) ◽  
pp. 029-044 ◽  
Author(s):  
S Calin Andras ◽  
J Brian Power ◽  
Edward C Cocking ◽  
Michael R Davey
Keyword(s):  
Nucleic Acid ◽  
Signal Amplification ◽  
Nucleic Acid Detection

A sensitive colorimetric assay system for nucleic acid detection based on isothermal signal amplification technology

2017 ◽  
Vol 409 (20) ◽  
pp. 4819-4825 ◽  
Author(s):  
Bo Hu ◽  
Jing Guo ◽  
Ying Xu ◽  
Hua Wei ◽  
Guojie Zhao ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Signal Amplification ◽  
Colorimetric Assay ◽  
Assay System ◽  
Nucleic Acid Detection

Recent advance in exonuclease Ⅲ-assisted target signal amplification strategy for nucleic acid detection

2021 ◽  
Author(s):  
hongyu liu ◽  
Yuhao You ◽  
Youzhuo Zhu ◽  
Heng Zheng
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Molecular Diagnostics ◽  
Mutation Analysis ◽  
Signal Amplification ◽  
Nucleic Acid Detection ◽  
Target Signal ◽  
Forensic Investigations ◽  
Exo Iii ◽  
Amplification Strategy

Detection of nucleic acids have become significantly important in molecular diagnostics, genetics therapy, mutation analysis, forensic investigations and biomedical development, and so on. In recent years, exonuclease Ⅲ (Exo III)...

Enzyme-assisted target recycling (EATR) for nucleic acid detection

2014 ◽  
Vol 43 (17) ◽  
pp. 6405-6438 ◽  
Author(s):  
Yulia V. Gerasimova ◽  
Dmitry M. Kolpashchikov
Keyword(s):  
Nucleic Acid ◽  
Signal Amplification ◽  
Nucleic Acid Detection ◽  
Target Recycling ◽  
Amplification Technique

Enzyme-assisted target recycling (EATR) is a signal amplification technique that can find application in PCR-free nucleic acid detection.

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