Phase composition and in-vitro bioactivity of plasma sprayed calcia stabilized zirconia coatings

The clinical use of plasma-sprayed hydroxyapatite (HA) coatings on metal implants has been widely investigated as the HA coating can achieve the firm and direct biological fixation with the surrounding bone tissue. It is shown in previous studies that the mechanical properties of HA coatings are improved by the addition of ZrO2 particles during the deposition of the coating on the substrate. Subsequently, the cohesive and adhesive strengths of plasma-sprayed hydroxyapatite (HA) coatings were strengthened by the ZrO2 particles addition as a reinforcing agent in the HA coating (HA+ZrO2 composite coating). The aim of the present work is to investigate and evaluate the in vitro bioactivity assessment of HA and HA/ZrO2 coatings, on stainless steel substrate, soaked in c-SBF, in order to study and compare their biological responses. The coatings were produced using vapor plasma spraying (VPS). The characterization of the surface of the coatings before and after soaking in SBF solution was performed using Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and X-ray Diffraction analysis (XRD). All samples were smoothed before insertion in the medium and the in vitro bioactivity of all coating samples was tested in conventional Simulated Body Fluid (c-SBF) solution for various immersion times.

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In Vitro Bioactivity, Cytotoxicity and Blood Compatibility of Anti-Bacterial Vacuum Plasma Sprayed Titanium Coatings

Materials Science Forum ◽

10.4028/www.scientific.net/msf.658.511 ◽

2010 ◽

Vol 658 ◽

pp. 511-514 ◽

Cited By ~ 2

Author(s):

Yi Kai Chen ◽

Xue Bin Zheng ◽

Ba Oe Li ◽

You Tao Xie ◽

Chuan Xian Ding

Keyword(s):

Direct Contact ◽

Body Fluid ◽

Blood Compatibility ◽

In Vitro Bioactivity ◽

Vacuum Plasma ◽

Titanium Coatings ◽

Good Biocompatibility ◽

Plasma Sprayed ◽

Direct Contact Test

Biomaterials with good biocompatibility and anti-bacterial property were becoming attractive to researchers, so we used the chemical method to produce anti-bacterial vacuum plasma sprayed titanium coatings and studied In vitro bioactivity, cytotoxicity and blood compatibility of the anti-bacterial coatings in this paper. In order to evaluate the bioactivity of the treated titanium coatings, the coatings were immersed in simulated body fluid (SBF). The treated titanium coatings showed good bioactivity in this experiment. Two different methods were used to assess the cytocompatibility of the treated titanium coatings. One was extract test; the other was direct contact test. The results indicated that cells spread and adhered well on the coatings. The blood compatibility of the coatings was evaluated by haemolysis ratios. The hemolysis ratios of the coatings were below 2%, indicating of nonhemolysis for the coatings.

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Preparation and Characterization of Bioactive and Magnetic Biphasic Thermo-Seeds Material

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.834-836.301 ◽

2013 ◽

Vol 834-836 ◽

pp. 301-304

Author(s):

Jian An Liu ◽

Xue Na Yang ◽

Mei Mei Zhang

Keyword(s):

Magnetic Property ◽

Phase Composition ◽

Glass Ceramic ◽

Body Fluid ◽

Glass Ceramics ◽

Magnetic Behavior ◽

In Vitro Bioactivity ◽

Magnetic Glass

A novel biphasic material has been synthesized from a melt-derived bioactive glass (45S5) and a glass-ceramic obtained from a melt-derived magnetic glass-ceramics for hyperthermia application. The biphasic material obtained from a mixture 1:1 of these components. The phase composition was investigated by XRD. The magnetic property was measured by VSM. The in vitro bioactivity was investigated by simulated body fluid (SBF) soaking experiment. The glass-ceramic shows magnetic behavior and bioactive, useful for hyperthermia.

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