Low-energy electron-beam modification of DLC coatings reduces cell count while maintaining biocompatibility

2018 ◽  
Vol 336 ◽  
pp. 34-38 ◽  
Author(s):  
G. Gotzmann ◽  
J. Beckmann ◽  
B. Scholz ◽  
U. Herrmann ◽  
C. Wetzel
Keyword(s):  
Electron Beam ◽  
Cell Count ◽  
Low Energy ◽  
Energy Electron ◽  
Dlc Coatings ◽  
Low Energy Electron

scholarly journals Long-term stable surface modification of DLC coatings

2017 ◽  
Vol 3 (2) ◽  
pp. 351-354 ◽  
Author(s):  
Gaby Gotzmann
Keyword(s):  
Surface Modification ◽  
Electron Beam ◽  
Biomedical Applications ◽  
Low Energy ◽  
Energy Electron ◽  
Electron Beam Treatment ◽  
Dlc Coatings ◽  
Low Energy Electron ◽  
The Stability

AbstractThe use of coatings based on diamond like carbon (DLC) for medical applications was established during the last years. Main advantages of these coatings are its high hardness, good wear and friction behavior and its biocompatibility. Using low-energy electron-beam treatment, we addressed the surface modification of DLC coatings. The aim was to generate new biofunctional surface characteristics that are long-term stable.Electron-beam modification resulted in significantly increased surface hydrophilicity, giving rise to the conclusion, that biological reaction on these surfaces will also be influenced by the modification. Furthermore, the stability of the surface modification was investigated. Therefore, the modified samples were stored for 8 weeks under ambient conditions. Additionally, the samples were stored in physiological saline solution at 37°C for 8 weeks. The stability of the modification was analyzed by contact angle measurement confirming no changes over the whole period of storage. In addition, the stability against standard cleaning and sterilization procedures was investigated. The durability of the modification to withstand these cleaning procedures was also proven.With these findings, the low-energy electron-beam modification seems to be a suitable tool for surface modification of DLC coatings. Thereby, the very good long-term stability is a great improvement in comparison to conventional surface modification methods like plasma treatment. In order to investigate the suitability of the modified coatings for biomedical applications, the cellular response was investigated using human fibroblasts, revealing a significantly reduced cell count on modified surfaces while maintaining their biocompatibility. By modification of the DLC surfaces, it is possible to adapt the cell adhesion on the treated surface areas. These findings demonstrate electron-beam treatment to be applicable for partial surface modification and functionalization within biomedical applications.

scholarly journals Dose-rate effect of low-energy electron beam irradiation on bacterial content in chilled turkey

2021 ◽  
Vol 640 (3) ◽  
pp. 032006
Author(s):  
U A Bliznyuk ◽  
P Yu Borchegovskaya ◽  
A P Chernyaev ◽  
V S Ipatova ◽  
V A Leontiev ◽  
...  
Keyword(s):  
Electron Beam ◽  
Dose Rate ◽  
Electron Beam Irradiation ◽  
Rate Effect ◽  
Low Energy ◽  
Energy Electron ◽  
Beam Irradiation ◽  
Low Energy Electron ◽  
Bacterial Content ◽  
Dose Rate Effect

New mask format for low-energy electron-beam proximity projection lithography

2002 ◽  
Author(s):  
Kaoru Koike ◽  
Shinji Omori ◽  
Kazuya Iwase ◽  
Isao Ashida ◽  
Shigeru Moriya
Keyword(s):  
Electron Beam ◽  
Low Energy ◽  
Energy Electron ◽  
Projection Lithography ◽  
Low Energy Electron

Low-Energy Electron Beam Extraction From Spherical Discharge

2011 ◽  
Vol 39 (11) ◽  
pp. 2554-2555 ◽  
Author(s):  
Mahdi Yousefi ◽  
Vahid Damideh ◽  
Hamid Ghomi
Keyword(s):  
Electron Beam ◽  
Low Energy ◽  
Energy Electron ◽  
Beam Extraction ◽  
Low Energy Electron
Sign in / Sign up

Export Citation Format

Share Document