In vitro and in vivo biocompatibility study of surface modified TiN deposited on Ti6Al4V using high-power impulse magnetron sputtering technique

2020 ◽  
Vol 394 ◽  
pp. 125814 ◽  
Author(s):  
Shu-Chuan Liao ◽  
Chih-Ying Chen ◽  
Yu-Hsuan Hsu ◽  
Chi-Ting Li ◽  
Cheng-Chi Hsieh ◽  
...  
Keyword(s):  
Magnetron Sputtering ◽  
High Power ◽  
Surface Modified ◽  
Biocompatibility Study

scholarly journals In vitro and in vivo biocompatibility study of polyacrylate TiO2@Ag coated nanoparticles for the radiation dose enhancement

2021 ◽  
Vol 49 (1) ◽  
pp. 185-193
Author(s):  
Ateeque Ur Rehman ◽  
Muhammad Hassan ◽  
Sadia Bano ◽  
Khizir Farooq ◽  
Aun Raza ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Dose Enhancement ◽  
Coated Nanoparticles ◽  
Biocompatibility Study

Calcium Phosphate Coating on Blast-Treated Titanium Implants by RF Magnetron Sputtering

2009 ◽  
Vol 631-632 ◽  
pp. 211-216 ◽  
Author(s):  
Kyosuke Ueda ◽  
Takayuki Narushima ◽  
Takashi Goto ◽  
T. Katsube ◽  
Hironobu Nakagawa ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Magnetron Sputtering ◽  
Bonding Strength ◽  
Rf Magnetron Sputtering ◽  
Titanium Implants ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating ◽  
Coating Films

Calcium phosphate coating films were fabricated on Ti-6Al-4V plates and screw-type implants with a blast-treated surface using radiofrequency (RF) magnetron sputtering and were evaluated in vitro and in vivo. Amorphous calcium phosphate (ACP) and oxyapatite (OAp) films obtained in this study could cover the blast-treated substrate very efficiently, maintaining the surface roughness. For the in vitro evaluations of the calcium phosphate coating films, bonding strength and alkaline phosphatase (ALP) activity were examined. The bonding strength of the coating films to a blast-treated substrate exceeded 60 MPa, independent of film phases except for the film after post-heat-treatment in silica ampoule. When compared with an uncoated substrate, the increase in the ALP activity of osteoblastic SaOS-2 cells on a calcium phosphate coated substrate was confirmed by a cell culture test. The removal torque of screw-type Ti-6Al-4V implants with a blast-treated surface from the femur of Japanese white rabbit increased with the duration of implantation and it was statistically improved by coating an ACP film 2 weeks after implantation. The in vitro and in vivo studies suggested that the application of the sputtered ACP film as a coating on titanium implants was effective in improving their biocompatibility with bones.

Biocompatibility of Surface-Modified Biphasic Calcium Phosphate/Poly-L-Lactide Biocomposite in vitro and in vivo

2010 ◽  
Vol 26 (8) ◽  
pp. 754-758 ◽  
Author(s):  
Weizhong Yang ◽  
Guangfu Yin ◽  
Dali Zhou ◽  
Jianwen Gu ◽  
Yadong Li ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Biphasic Calcium Phosphate ◽  
Surface Modified

Formation and In Vitro and In Vivo Evaluation of Surface Modified Implants by HAp, Carbonated-HAp and Titanium Oxide

2007 ◽  
Vol 539-543 ◽  
pp. 687-691 ◽  
Author(s):  
Masazumi Okido ◽  
Ryoichi Ichino ◽  
Kotaro Kuroda
Keyword(s):  
Titanium Oxide ◽  
Titanium Implant ◽  
Titanium Implants ◽  
Contact Ratio ◽  
In Vivo Evaluation ◽  
Ft Ir ◽  
Mouse Osteoblast ◽  
Surface Modified

Hydroxyapatite (Ca10(PO4)6(OH)2, HAp), carbonated HAp and titanium oxide are of interest for bone-interfacing implant applications, because of their demonstrated osteoconductive properties. They were coated on the titanium implants and investigated the in vitro and in vivo performance. HAp coatings were performed by the thermal substrate method in aqueous solutions. Titanium oxide film was also formed on the titanium implants by gaseous oxidation, or by anodizing in the acidic solution. All the specimens covered with HAp, carbonated HAp or TiO2 (rutile or anatase). were characterized by XRD, EDX, FT-IR and SEM. In the in vitro testing, the mouse osteoblast-like cells (MC3T3-E1) were cultured on the coated and non-coated specimens for up to 30 days. Moreover, the osseointegration was evaluated from the rod specimens implanted in rats femoral for up to 8 weeks. In in vivo evaluations two weeks postimplantation, new bone formed on the coated and non-coated titanium rods in the cancellous bone and cortical bone, respectively. Bone-implant contact ratio, in order to evaluate of new bone formation, was significantly depended on the compound formed on the titanium implant.

Synthesis and characterization of surface‐modified PBLG nanoparticles for bone targeting: In vitro and in vivo evaluations

2011 ◽  
Vol 100 (11) ◽  
pp. 4877-4887 ◽  
Author(s):  
İpek Özcan ◽  
Kawthar Bouchemal ◽  
Freimar Segura‐Sánchez ◽  
Özgen Özer ◽  
Tamer Güneri ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Bone Targeting ◽  
Surface Modified
Sign in / Sign up

Export Citation Format

Share Document