scholarly journals Corrigendum to “Single virus inductively coupled plasma mass spectroscopy analysis: A comprehensive study” [Talanta 228 (2021) 122211]

Talanta ◽  
2021 ◽  
pp. 122382
Author(s):  
Claude Degueldre
Keyword(s):  
Mass Spectroscopy ◽  
Inductively Coupled Plasma ◽  
Spectroscopy Analysis ◽  
Inductively Coupled ◽  
Mass Spectroscopy Analysis ◽  
Comprehensive Study

scholarly journals Lichen Sebagai Bioindikator Pencemaran Udara Di Gerbang Kota (Gateway) Kota Jambi

2021 ◽  
Vol 4 (1) ◽  
pp. 6
Author(s):  
Febri Juita Anggraini ◽  
Ria Resti Oktapiani ◽  
Freddy Ilfan ◽  
Zuli Rodhiyah
Keyword(s):  
Air Pollution ◽  
Inductively Coupled Plasma ◽  
Traffic Density ◽  
Sampling Location ◽  
Spectroscopy Analysis ◽  
Inductively Coupled ◽  
Point Of Entry ◽  
Icp Ms ◽  
Measurement Results ◽  
Mass Spectroscopy Analysis

The gateway of city is the point of entry and exit for traffic activities, the high traffic activity that occurs causes air pollution, thereby reducing air quality. The use of lichen as a bioindicator is considered more efficient than using other indicator tools or machines. Purpose of this study was to determine the level of air pollution at the gateway of Jambi city using lichen as a bioindicator and to determine the concentration of Pb metal content in lichen. The research method used is exploration with roaming methods. The location of the research was carried out at the West Gate of Simpang Rimbo, the South Gate of Paal 10, and the East Gate of Aurduri 2. The Pb metal test in lichen was carried out using Inductively Coupled Plasma Mass Spectroscopy analysis method (ICP-MS). Based on the measurement results, the Aurduri 2 location is included in the location of low traffic density with an average number of 18,509 vehicles/ day. The location with moderate traffic density is Paal 10 with an average number of 31,941 vehicles/ day. The vehicle traffic density with the highest number was the Simpang Rimbo location with an average number of 45,041 vehicles/ day. The highest concentration of Pb in lichen was at the Aurduri 2 sampling location with a Pb metal value of 3.01 ppm and the lowest at the Simpang Rimbo location of 2.31 ppm.

EXTH-82. T CELL HITCHHIKING AS A MECHANISM OF DRUG DELIVERY TO THE BRAIN

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi182-vi182
Author(s):  
Kirit Singh ◽  
Patrick Gedeon ◽  
Teilo Schaller ◽  
David Snyder ◽  
Mustafa Khasraw ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Median Survival ◽  
Mass Spectroscopy ◽  
Ct Imaging ◽  
Spectroscopy Analysis ◽  
Activated T Cells ◽  
Pet Ct ◽  
The Brain ◽  
Mass Spectroscopy Analysis

Abstract INTRODUCTION The blood-brain barrier (BBB) restricts access to the central nervous system (CNS). Our brain bispecific T cell engager (hEGFRvIII:CD3 BRiTE) treats subcutaneous syngeneic tumor (CT2AvIII) but not intracranial CT2AvIII. CD3 engaging molecules such as nanoparticles can be carried into the brain by binding to activated T cells. We therefore sought to determine if co-administration of larger molecules (BRiTE, approx. 55kDa) with activated T cells could cross the BBB, enhancing survival. METHODS We implanted 8–10-week-old transgenic hCD3 mice (n=7-8 per group) with 30,000 CT2AvIII cells. Tumors were established for 6 days. Mice were administered either (1) autologous lymphocyte transfer (ALT) alone (single intravenous (IV) injection, 1 x 107 activated T cells), (2) serial IV BRiTE doses (50ug, 10 days) (3) BRiTE and ALT or (4) no treatment. Mice were followed for survival using Kaplan-Meier curves and compared via log rank test. Targeted mass spectroscopy analysis as well as PET/CT imaging of mice administered Iodine-124 radiolabelled BRiTE was performed to assess for intracranial accumulation. RESULTS Mice who received BRiTE and ALT demonstrated significantly enhanced survival compared to controls (median survival 29 vs 21 days, p=0.0135). Mice who received only BRiTE or ALT exhibited median survival comparable to controls (p=0.192, p=0.944 respectively). Mass spectroscopy analysis revealed that mice had a 7-fold increased peak area ratio of BRiTE in the CNS when co-treated with activated T cells compared to BRiTE alone (0.14, 0.02 respectively) while PET/CT imaging demonstrated increased radioactive signal over background localized to coordinates within the brain where tumors were injected. CONCLUSIONS Giving activated T cells alongside BRiTE allows better access to the intracranial compartment and is required to achieve efficacy in mice with syngeneic orthotopic glioma. Future work will determine the optimal dose and schedule for this approach, as well as defining the precise mechanism by which this occurs.

scholarly journals 5,5′-Oxybis(1,3,7-trihydroxy-9H-xanthen-9-one): A New Xanthone from the Stem Bark of Garcinia porrecta (Clusiaceae)

Molbank ◽  
10.3390/m1153 ◽  
2020 ◽  
Vol 2020 (3) ◽  
pp. M1153
Author(s):  
Ayu N. Safitri ◽  
Nurlelasari ◽  
Tri Mayanti ◽  
Darwati ◽  
Unang Supratman
Keyword(s):  
High Resolution ◽  
Mass Spectroscopy ◽  
Spectroscopic Data ◽  
2D Nmr ◽  
Stem Bark ◽  
Spectroscopy Analysis ◽  
High Resolution Mass ◽  
High Resolution Mass Spectroscopy ◽  
Mass Spectroscopy Analysis ◽  
Resolution Mass

A new polyoxygenated dimer-type xanthone, namely 5,5′-oxybis(1,3,7-trihydroxy-9H-xanthen-9-one (1), has been isolated from the stem bark of Garcinia porrecta. The structure of 1 was determined based on spectroscopic data, including 1D and 2D-NMR as well as high resolution mass spectroscopy analysis.

Sign in / Sign up

Export Citation Format

Share Document