In this chapter, Gimena del Río Riande, the Argentine researcher based at the National Scientific and Technical Research Council (CONICET), talks about the state of the digital humanities in Argentina and the potential implications and promise of digital research in Latin American academia. She explains the specific challenges in the region and how technologies are playing a defining role in the reshaping of Latin American humanities at the dawn of the 21st century. As expected, the way in which the humanidades digitales developed in Spanish-speaking countries differs significantly from that of the Anglophone digital humanities. These differences can be found not only in the language that communicates research—all the different variants of Spanish—but also in the topics, methods, and tools, due to the diverse academic, cultural, and economic contexts. To illustrate this, Gimena del Río tells us how she started working in 2013 on the creation of a digital humanities community in Argentina, the Asociación Argentina de Humanidades Digitales (AAHD), and the digital humanities projects she is currently coordinating.