In vivo comparison of the biocompatibility of two root canal sealers implanted into the subcutaneous connective tissue of rats

2007 ◽  
Vol 103 (5) ◽  
pp. e88-e94 ◽  
Author(s):  
Edilson José Zafalon ◽  
Marco Aurélio Versiani ◽  
Cássio José Alves de Souza ◽  
Camila Christian Gomes Moura ◽  
Paula Dechichi
Keyword(s):  
Connective Tissue ◽  
Root Canal ◽  
Subcutaneous Connective Tissue ◽  
Root Canal Sealers

In vivo comparison of the biocompatibility of two root canal sealers implanted into the subcutaneous connective tissue of rats

1998 ◽  
Vol 24 (2) ◽  
pp. 82-85 ◽  
Author(s):  
Ioannis Kolokouris ◽  
Nikolaos Economides ◽  
Panagiotis Beltes ◽  
Ioannis Vlemmas
Keyword(s):  
Connective Tissue ◽  
Root Canal ◽  
Subcutaneous Connective Tissue ◽  
Root Canal Sealers

scholarly journals Tissue toxicity of root canal sealers

2004 ◽  
Vol 51 (3) ◽  
pp. 136-141 ◽  
Author(s):  
Mirjana Vujaskovic ◽  
Dragoljub Bacetic
Keyword(s):  
Connective Tissue ◽  
Root Canal ◽  
Tissue Reaction ◽  
Tissue Response ◽  
Control Material ◽  
Tissue Sections ◽  
Subcutaneous Connective Tissue ◽  
Tissue Reactions ◽  
Root Canal Sealers ◽  
Observation Period

The aim of this study was to evaluate tissue response to root canal sealers Tubuliseal and Sealapex. The sealers were freshly mixed and injected in the dorsal subcutaneous connective tissue of 12 Wistar rats.The observation periods were 7 days, 21days and 60 days. Four operative areas were formed ( 2 for test sealers, Tubliseal or Sealapex and 2 for control material) on each animal. Tissue sections were taken from selected sites. Each section included skin, subcutaneous connective tissue and underlying muscle tissue.All blocks were processed with the use of standardized histological procedures.The tissue reactions were studied under light microscopy. Different grades of tissue reaction to the tested materials were recorded as mild, moderate or severe inflammation. After seven days both root canal sealers showed severe inflammatory reaction of connective tissue in experimental animals.Tubuliseal caused prolonged moderate and mild inflammation. Sealapex caused mild inflammation which diminished at the end of the observation period. The results of this study demonstrated that Sealapex was better tolerated by tissue than Tubliseal.

scholarly journals Συμβολή εις την μελέτην της αξίας ενιών εμφρακτικών υλικών των ριζικών σωληνών δια ραδιενεργών ισοτόπων (S35)

1967 ◽  
Author(s):  
Ζαχαρίας Μαντζαβίνος
Keyword(s):  
Root Canal ◽  
Multiple Point ◽  
Multiple Points ◽  
Single Root ◽  
Gutta Percha ◽  
Silver Point ◽  
Autoradiographic Technique ◽  
Root Canal Sealers

The present study was performed in order to evaluate, by the autoradiographic technique the sealing properties of three root canal sealers, combined with gutta - percha and silver points, in vitro. A total of one hundred and five extracted human, single root teeth were used and divided into five groups according to the filling combinations tested. The teeth were filled, using two techniques, of the single and multiple points. Autoradiographies, using S35, in all instances, were performed and the results obtained were compared with the respective dental radiograms The obtained results lead to the following conclusions: 1. Silver and gutta - percha points may be always combined with sealers. Otherwise the root canal is not adequately sealed. 2. A gutta - percha point, without sealer, produced a superior filling to silver point. 3. It seems possible to obtain a complete obturation of the rootcanal with the combination of gutta - percha and Grosman’s Sealer using the multiple - point technique. 4. It follows in effectivness, the combination of silver point and Grossman’s sealer.5. The combination of gutta - percha point with Zinc - oxide eugenol sealer and chloropercha are the least efficient. 6. Finally it must be stressed that since the conditions of the present study do not correspond exactly to those encountered in vivo, extrapolation of the results obtained, to man has to be performed with caution.

Comparison of calcium and hydroxyl ion release ability and in vivo apatite-forming ability of three bioceramic-containing root canal sealers

2021 ◽  
Author(s):  
Razi Saifullah Ibn Belal ◽  
Naoki Edanami ◽  
Kunihiko Yoshiba ◽  
Nagako Yoshiba ◽  
Naoto Ohkura ◽  
...  
Keyword(s):  
Root Canal ◽  
Ion Release ◽  
Hydroxyl Ion ◽  
Root Canal Sealers

In vivo sealing ability of calcium hydroxide-containing root canal sealers

1989 ◽  
Vol 5 (1) ◽  
pp. 23-26 ◽  
Author(s):  
Frederic Barnett ◽  
Martin Trope ◽  
Jane Rooney ◽  
Leif Tronstad
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Sealing Ability ◽  
Root Canal Sealers

The Biophysical Response of Collagen-Fibrin Composite Gels to In Vitro Acupuncture

2010 ◽  
Author(s):  
Margaret Julias ◽  
Helen M. Buettner ◽  
David I. Shreiber
Keyword(s):  
Connective Tissue ◽  
Ex Vivo ◽  
Phenotypic Changes ◽  
Composite Gels ◽  
Subcutaneous Connective Tissue

Therapeutic acupuncture involves the insertion and manipulation of fine needles at specific points. Although acupuncture has been proven effective for a number of conditions, the mechanisms that underlay these effects remain unknown. A critical first step is to identify the local changes that occur during needle manipulation, which can then be related to longer-term and more remote consequences. In vivo and ex vivo studies have demonstrated that loose collagenous subcutaneous connective tissue couples to needles during therapeutic manipulation, which deforms the tissue and exposes resident cells to altered mechanics and triggers morphologic and phenotypic changes. The resultant alignment of the tissue and cells may additionally help to propagate signals along acupuncture meridians.

In vivo comparison of the biocompatibility of two root canal sealers implanted into the mandibular bone of rabbits

1992 ◽  
Vol 73 (5) ◽  
pp. 613-620 ◽  
Author(s):  
Wilhelm-Joseph Pertot ◽  
Jean Camps ◽  
Mireille Remusat ◽  
Jean-Pierre Proust
Keyword(s):  
Root Canal ◽  
Mandibular Bone ◽  
Root Canal Sealers

scholarly journals Biocompatibility of four root canal sealers: a histopathological evaluation in rat subcutaneous connective tissue

2011 ◽  
Vol 22 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Camila Maggi Maia Silveira ◽  
Shelon Cristina Souza Pinto ◽  
Rosário de Arruda Moura Zedebski ◽  
Fábio André Santos ◽  
Gibson Luiz Pilatti
Keyword(s):  
Connective Tissue ◽  
Inflammatory Reaction ◽  
Root Canal ◽  
Descriptive Analysis ◽  
Giant Cells ◽  
Tissue Samples ◽  
Inflammatory Reactions ◽  
Ah Plus ◽  
Severe Inflammatory Reaction ◽  
Root Canal Sealers

The aim of this study was to evaluate the subcutaneous biocompatibility of: Epiphany, AH Plus, Pulp Canal Sealer and Sealapex root canal sealers. Sixty rats were randomly assigned to 4 groups, according to the sealer. Polyethylene tubes containing the tested materials were inserted into the connective tissue. The implants were removed after 7, 15 and 30 days, and the tissue samples were processed, stained and examined by light microscopy. The descriptive analysis considered: thickness of the fibrous capsule, severity of the inflammatory reaction, and presence of giant cells. After 7 days, all sealers induced moderate to severe inflammatory reaction. After 15 days, Epiphany and AH Plus sealers showed a moderate inflammatory reaction, while Pulp Canal Sealer and Sealapex induced severe and mild inflammatory reactions, respectively. After 30 days, mild inflammatory reactions were observed for Epiphany, Sealapex and AH Plus. Sealapex induced the lowest inflammatory response at all evaluation periods, and only Pulp Canal Sealer did not show a decreased in the inflammatory reaction over time.

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