AuNPs(EDAS) – rGO nanocomposites were prepared by a facile one step sonochemical synthesis process. Here, EDAS acts as an interlinker for anchoring gold on rGO and it also acts both as a reducing agent and a stabilizing agent. The AuNPs(EDAS) – rGO nanocomposites show excellent electro-catalytic activity towards oxidation of DA and UA. The AuNPs(EDAS) – rGO nanocomposites exhibit low detection limits, high sensitivity, it could be a potential candidate for sensing application and in biosensor technology in the future.