scholarly journals Expansion of the 1st WHO international standard for antiserum to respiratory syncytial virus to include neutralisation titres against RSV subtype B: An international collaborative study

Vaccine ◽  
2020 ◽  
Vol 38 (4) ◽  
pp. 800-807
Author(s):  
Jacqueline U. McDonald ◽  
Peter Rigsby ◽  
Eleanor Atkinson ◽  
Othmar G. Engelhardt
Keyword(s):  
Respiratory Syncytial Virus ◽  
Collaborative Study ◽  
International Standard ◽  
Subtype B ◽  
International Collaborative ◽  
Syncytial Virus ◽  
International Collaborative Study

A Collaborative Study Designed to Establish the 4th International Standard for Heparin

1984 ◽  
Vol 52 (02) ◽  
pp. 148-153 ◽  
Author(s):  
D P Thomas ◽  
A D Curtis ◽  
T W Barrowcliffe
Keyword(s):  
Collaborative Study ◽  
International Standard ◽  
Thrombin Inhibition ◽  
Freeze Dried ◽  
Assay Methods ◽  
The Mean ◽  
International Collaborative ◽  
International Collaborative Study

SummaryAn international collaborative study, in which 22 laboratories participated, was carried out to establish a replacement for the International Standard for Heparin. A total of 248 assays were analyzed, including APTT, thrombin inhibition and anti-Xa assays, as well as pharmacopoeial assays. Overall, there was less than 5% difference in the mean potency estimates of the candidate preparations, by all assay methods. The freeze-dried preparation 82/502 demonstrated the closest parallelism by bioassay to the existing standard and was established by WHO as the 4th International Standard for Heparin, with an assigned unitage of 1780 i.u. per ampoule.

scholarly journals The third international standard for anti‐D immunoglobulin: international collaborative study to evaluate candidate preparations

Vox Sanguinis ◽  
2019 ◽  
Vol 114 (7) ◽  
pp. 740-748 ◽  
Author(s):  
Bernard Fox ◽  
Giles Sharp ◽  
Eleanor Atkinson ◽  
Graham Roberts ◽  
Peter Rigsby ◽  
...  
Keyword(s):  
Collaborative Study ◽  
International Standard ◽  
The Third ◽  
International Collaborative ◽  
International Collaborative Study

scholarly journals International collaborative study to evaluate a recombinant L ferritin preparation as an International Standard

1997 ◽  
Vol 43 (9) ◽  
pp. 1582-1587 ◽  
Author(s):  
Susan J Thorpe ◽  
Dawn Walker ◽  
Paolo Arosio ◽  
Alan Heath ◽  
James D Cook ◽  
...  
Keyword(s):  
Collaborative Study ◽  
Expert Committee ◽  
Immunological Reactivity ◽  
International Standard ◽  
Accelerated Degradation ◽  
Wide Range ◽  
Biological Standardization ◽  
International Collaborative ◽  
Degradation Studies ◽  
International Collaborative Study

Abstract A recombinant L ferritin preparation, lyophilized in ampoules and designated 94/572, was evaluated by 18 laboratories in 9 countries for its suitability as an International Standard (IS). The preparation was assayed in a wide range of in-house and commercial immunoassays against the 2nd IS for ferritin (of spleen origin; 80/578). The immunological reactivity of the recombinant material was similar to that of the 2nd IS for ferritin in the majority of assays and demonstrated adequate stability in accelerated degradation studies. On the basis of the results presented here, the WHO Expert Committee on Biological Standardization established 94/572 as the 3rd IS for ferritin, recombinant.

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