Regionalisation: A strategy that will assist with bovine tuberculosis control and facilitate trade

2006 ◽  
Vol 112 (2-4) ◽  
pp. 291-301 ◽  
Author(s):  
P.G. Livingstone ◽  
T.J. Ryan ◽  
N.G. Hancox ◽  
K.B. Crews ◽  
M.A.J. Bosson ◽  
...  
2019 ◽  
Vol 7 (2) ◽  
pp. 75
Author(s):  
Gerlane Nunes Noronha ◽  
Marcos Antônio Souza dos Santos ◽  
Washington Luiz Assunção Pereira ◽  
Alexandre Do Rosário Casseb ◽  
Andréia Santana Bezerra ◽  
...  

The article identifies the main pathologies found and estimates the economic losses generated in a slaughterhouse in the Thailand municipality, Pará, during the period from March 2010 to October 2014. 55,169 animals were slaughtered, with total economic losses of R$ 1,221,035.90 and ischemia was the most frequent lesion (41.86%). The most frequent condemnation organs were lungs (48.75%), kidneys (41.66%) and liver (3.61%), which produced economic loss of R$ 76,405.65 (6.26%). Tuberculosis was the main cause of carcass condemnation, responsible for R$ 872,783.64 of economic losses. The bovine tuberculosis control can begin in production, with examinations on the farm to slaughter lines, with careful carcass inspection, as advocated by the National Program for the Control and Eradication of Animal Brucellosis and Tuberculosis (PNCEBT), which increases disease control and minimizes condemnations and economic losses at slaughter.


1997 ◽  
Vol 264 (1384) ◽  
pp. 1069-1076 ◽  
Author(s):  
R. R. Kao ◽  
M. G. Roberts ◽  
T. J. Ryan

2013 ◽  
Vol 112 (3-4) ◽  
pp. 266-275 ◽  
Author(s):  
Rebecca L. Smith ◽  
Loren W. Tauer ◽  
Ynte H. Schukken ◽  
Zhao Lu ◽  
Yrjo T. Grohn

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0142710 ◽  
Author(s):  
Catherine M. Smith ◽  
Sara H. Downs ◽  
Andy Mitchell ◽  
Andrew C. Hayward ◽  
Hannah Fry ◽  
...  

2017 ◽  
Author(s):  
Freya Smith ◽  
Andrew Robertson ◽  
Graham C. Smith ◽  
Peter Gill ◽  
Robbie A. McDonald ◽  
...  

AbstractVaccination is a potentially useful approach for the control of disease in wildlife populations. The effectiveness of vaccination is contingent in part on obtaining adequate vaccine coverage at the population level. However, measuring vaccine coverage in wild animal populations is challenging and so there is a need to develop robust approaches to estimate coverage and so contribute to understanding the likely efficacy of vaccination.We used a modified capture mark recapture technique to estimate vaccine coverage in a wild population of European badgers (Meles meles) vaccinated by live-trapping and injecting with Bacillus Calmette-Guérin as part of a bovine tuberculosis control initiative in Wales, United Kingdom. Our approach used genetic matching of vaccinated animals to a sample of the wider population to estimate the percentage of badgers that had been vaccinated. Individual-specific genetic profiles were obtained using microsatellite genotyping of hair samples which were collected both directly from trapped and vaccinated badgers and non-invasively from the wider population using hair traps deployed at badger burrows.We estimated the percentage of badgers vaccinated in a single year and applied this to a simple model to estimate cumulative vaccine coverage over a four year period, corresponding to the total duration of the vaccination campaign.In the year of study, we estimated that between 44-65% (95% confidence interval, mean 55%) of the badger population received a vaccine dose. Using the model, we estimated that 70-85% of the total population would have received at least one vaccine dose over the course of the four year vaccination campaign.This study represents the first application of this novel approach for measuring vaccine coverage in wildlife. This is also the first attempt at quantifying the level of vaccine coverage achieved by trapping and injecting badgers. The results therefore have specific application to bovine tuberculosis control policy, and the approach is of significance to the wider field of wildlife vaccination.


2013 ◽  
Vol 141 (7) ◽  
pp. 1382-1389 ◽  
Author(s):  
J. HONE

SUMMARYMycobacterium bovis causes bovine tuberculosis (bTB) in many mammals including cattle, deer and brushtail possum. The aim of this study was to estimate the strength of association, using model selection (AICc) regression analyses, between the proportion of cattle and farmed deer herds with bTB in New Zealand and annual costs of TB control, namely disease control in livestock, in wildlife or in a combination of the two. There was more support for curved (concave up) than linear models which related the proportion of cattle and farmed deer herds with bTB to the annual control costs. The curved, concave-up, best-fitting relationships showed diminishing returns with no positive asymptote and implied TB eradication is feasible in New Zealand.


2013 ◽  
Vol 20 (12) ◽  
pp. 1827-1835 ◽  
Author(s):  
K. E. Bass ◽  
B. J. Nonnecke ◽  
M. V. Palmer ◽  
T. C. Thacker ◽  
R. Hardegger ◽  
...  

ABSTRACTCurrently, the Bovigam assay is used as an official supplemental test within bovine tuberculosis control programs. The objectives of the present study were to evaluate twoMycobacterium bovis-specific peptide cocktails and purified protein derivatives (PPDs) from two sources, liquid and lyophilized antigen preparations. PPDs and peptide cocktails were also used for comparison of a second-generation gamma interferon (IFN-γ) release assay kit with the currently licensed first-generation kit (Bovigam; Prionics AG). Three strains ofM. boviswere used for experimental challenge:M. bovis95-1315,M. bovisRavenel, andM. bovis10-7428. Additionally, samples from a tuberculosis-affected herd (i.e., naturally infected) were evaluated. Robust responses to both peptide cocktails, HP (PC-HP) and ESAT-6/CFP10 (PC-EC), and the PPDs were elicited as early as 3 weeks after challenge. Only minor differences in responses to Commonwealth Serum Laboratories (CSL) and Lelystad PPDs were detected with samples from experimentally infected animals. For instance, responses to LelystadM. avium-derived PPD (PPDa) exceeded the respective responses to the CSL PPDa inM. bovisRavenel-infected and control animals. However, a 1:4 dilution of stimulated plasma demonstrated greater separation of PPDb from PPDa responses (i.e., PPDb minus PPDa) with the use of Lelystad PPDs, suggesting that Lelystad PPDs provide greater diagnostic sensitivity than CSL PPDs. The responses to lyophilized and liquid antigen preparations did not differ. Responses detected with first- and second-generation IFN-γ release assay kits (Bovigam) did not differ throughout the study. In conclusion, antigens may be stored in a lyophilized state without loss in potency, PC-HP and PC-EC are dependable biomarkers for aiding in the detection of bovine tuberculosis, and second-generation Bovigam kits are comparable to currently used kits.


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