Inhibitory effects of recombinant porcine interferon-α on porcine transmissible gastroenteritis virus infections in TGEV-seronegative piglets

2021 ◽  
Vol 252 ◽  
pp. 108930
Author(s):  
Dong-Mei Gao ◽  
Hai-Yang Yu ◽  
Wei Zhou ◽  
Bing-Bing Xia ◽  
Hong-Zhang Li ◽  
...  
Keyword(s):  
Transmissible Gastroenteritis Virus ◽  
Interferon Α ◽  
Virus Infections ◽  
Inhibitory Effects ◽  
Gastroenteritis Virus ◽  
Porcine Transmissible Gastroenteritis Virus ◽  
Transmissible Gastroenteritis

scholarly journals Recombinant Canine Coronaviruses Related to Transmissible Gastroenteritis Virus of Swine Are Circulating in Dogs

2008 ◽  
Vol 83 (3) ◽  
pp. 1532-1537 ◽  
Author(s):  
Nicola Decaro ◽  
Viviana Mari ◽  
Marco Campolo ◽  
Alessio Lorusso ◽  
Michele Camero ◽  
...  
Keyword(s):  
Genetic Relatedness ◽  
The Other ◽  
Spike Protein ◽  
Transmissible Gastroenteritis Virus ◽  
Type Ii ◽  
Internal Organs ◽  
Systemic Involvement ◽  
Gastroenteritis Virus ◽  
Porcine Transmissible Gastroenteritis Virus ◽  
Transmissible Gastroenteritis

ABSTRACT Four canine coronavirus type II (CCoV-II) strains were identified in the guts and internal organs of pups which had died of acute gastroenteritis. The CCoV-II strains were strictly related to porcine transmissible gastroenteritis virus (TGEV) in the N-terminal domain of the spike protein, whereas in the other parts of the genome, a higher genetic relatedness to recent CCoV-II isolates was observed. Experimental infection of dogs with a TGEV-like isolate induced mild gastroenteritis without any systemic involvement. By virus neutralization tests, antigenic differences between reference and TGEV-like CCoVs were found. Our data support the potential recombinant origin of the TGEV-like CCoVs.

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