Executive dysfunction in children and adolescents with temporal lobe epilepsy: Is the Wisconsin Card Sorting Test enough?

2009 ◽  
Vol 15 (3) ◽  
pp. 376-381 ◽  
Author(s):  
Patricia Rzezak ◽  
Daniel Fuentes ◽  
Catarina A. Guimarães ◽  
Sigride Thome-Souza ◽  
Evelyn Kuczynski ◽  
...  
2010 ◽  
Vol 17 (1) ◽  
pp. 39-45 ◽  
Author(s):  
Arlety Garcia Espinosa ◽  
René Andrade Machado ◽  
Susana Borges González ◽  
María Eugenia García González ◽  
Ariadna Pérez Montoto ◽  
...  

1996 ◽  
Vol 18 (2) ◽  
pp. 310-313 ◽  
Author(s):  
Michael David Horner ◽  
Laura A. Flashman ◽  
David Freides ◽  
Charles M. Epstein ◽  
Roy A. E. Bakay

2007 ◽  
Vol 1 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Luciana Tisser ◽  
Andre Palmini ◽  
Eliseu Paglioli ◽  
Mirna Portuguez ◽  
Ney Azambuja ◽  
...  

Abstract Patients with temporal lobe epilepsy due to hippocampal sclerosis (TLE/HS) have a distinct neuropsychological profile, but there is still debate on whether executive dysfunction is part of this profile and also whether temporal lobe surgery can modify this dysfunction. Objective: To study the presence and reversibility of executive dysfunction in patients with unilateral TLE/HS. Methods: Twenty-five patients with refractory seizures due to TLE/HS underwent presurgical evaluation which included the application of the Wiconsin Card Sorting Test (WCST). Nineteen were re-evaluated in follow up, at least 6 months after selective amygdalo-hippocampectomy (SAH). Twenty-two control subjects matched for age and education also performed the WCST. Results: Sixteen of the 25 patients (64%) completed fewer than four categories in the WCST whereas only 4 of the 22 controls (18%) did not complete at least four categories (p<0.005). In addition, the performance of the patients involved significantly more perseverative responses and errors compared to controls. The patient group demonstrated significant post-operative improvement in many measures of the WCST following SAH. Conclusions: These findings support the presence of executive dysfunction in patients with TLE/HS and suggest that such dysfunction can be partially reversed by selective resection of epileptogenic mesial temporal structures.


2002 ◽  
Vol 24 (3) ◽  
pp. 174-178 ◽  
Author(s):  
Kazue Igarashi ◽  
Hirokazu Oguni ◽  
Makiko Osawa ◽  
Yutaka Awaya ◽  
Motoichiro Kato ◽  
...  

2014 ◽  
Vol 17 ◽  
Author(s):  
Tânia Silva ◽  
Luís Monteiro ◽  
Emanuela Lopes

AbstractAlthough several brief sensitive screening tools are available to detect executive dysfunction, few have been developed to quickly assess executive functioning. The INECO Frontal Screening (IFS) is a brief tool which has proved be useful for the assessment of the executive functions in patients with dementia. The aim of this study was to explore whether the IFS is as sensitive and specific as the BADS, a battery designed to assess the dysexecutive syndrome, in schizophrenia. Our sample comprised a group of 34 schizophrenic patients (Mean age = 39.59, DP = 10.697) and 31 healthy controls (Mean age = 35.52, DP = 10.211). To all groups were administered the BADS, Wisconsin Card Sorting Test and IFS. The results suggest that schizophrenic patients performed significantly worse than the control group in all tests (p < .05). The IFS total score was 13.29 for the experimental group and 26.21 for the control group (p < .001). Considering a cut-off of 14 points, the IFS sensitivity was 100% and specificity 56% in detection of executive dysfunction in schizophrenia, compared with the BADS, that if we consider a cut-off of 11 points, was a sensitivity of 100% and a specificity of 50%. Thus, IFS is a brief, sensitive and specific tool for the detection of executive dysfunction in schizophrenia.


2001 ◽  
Vol 7 (3) ◽  
pp. 344-352 ◽  
Author(s):  
WILLIAM PERRY ◽  
ERIC G. POTTERAT ◽  
DAVID L. BRAFF

Patients with schizophrenia have Wisconsin Card Sorting Test (WCST) deficits, which are commonly interpreted as reflecting frontal cortex-based executive dysfunction. One means of assessing the refractoriness of frontal-executive impairment is to utilize a training or modification strategy to improve WCST performance. In this study, 73 patients with schizophrenia were assigned to 1 of 2 groups. Group 1 received the standard WCST instructions for 64 cards (Condition 1). For the second 64-card deck, the patients were asked to verbalize the reason that they placed the card where they did after each sort (Condition 2). Group 2 received this modified instruction 1st (Condition 1) and then the standard instructions for the second deck (Condition 2). A group of normal comparison participants was also tested using standard instructions alone. Group 2 committed significantly fewer perseverative responses than did Group 1. Furthermore, there was no significant difference between Group 2 (Condition 1) and the normal participants. Group 1's performance improved when patients were exposed to the modified instructions (Condition 2). Additionally, poor premorbid factors and disorganized symptoms were associated with decreased benefit from the modified instructions across both groups. Cumulatively, these data suggest that a simple instruction may enhance executive function and impact WCST performance in patients with schizophrenia. (JINS, 2001, 7, 344–352.)


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