Effects of long-term epilepsy and of temporal lobe resection on cognitive aging

2013 ◽  
Vol 28 (2) ◽  
pp. 308-309
Author(s):  
M. Jones-Gotman ◽  
S.J. Banks
Neurology ◽  
1997 ◽  
Vol 48 (3) ◽  
pp. 621-626 ◽  
Author(s):  
S. D. Eliashiv ◽  
S. Dewar ◽  
I. Wainwright ◽  
J. Engel ◽  
I. Fried

Neurology ◽  
1997 ◽  
Vol 48 (5) ◽  
pp. 1383-1388 ◽  
Author(s):  
S. D. Eliashiv ◽  
S. Dewar ◽  
I. Wainwright ◽  
J. Engel ◽  
I. Fried

2016 ◽  
Vol 64 (2) ◽  

Strategies to improve cognitive aging are highly needed. Among those, promotion of exercise and physical activity appears as one of the most attractive and beneficial intervention. Indeed, results from basic and clinical studies suggest that exercise and physical activity have positive effects on cognition in older persons without cognitive impairment, as well as in those with dementia. Despite inconsistent results, aerobic exercise appears to have the strongest potential to enhance cognition. However, even limited periods of walking (45 minutes, three times a week, over a 6-month period) have also been shown to enhance cognition, particularly executive functions. Changing long-term lifestyle habits in these older persons remains a critical challenge and attractive programs susceptible to gain adherence are needed to succeed in achieving improved cognitive aging.


Epilepsia ◽  
1996 ◽  
Vol 37 (7) ◽  
pp. 651-656 ◽  
Author(s):  
Gregory D. Cascino ◽  
Max R. Trenerry ◽  
Elson L. So ◽  
Frank W. Sharbrough ◽  
Cheolsu Shin ◽  
...  

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2016 ◽  
Vol 57 (11) ◽  
pp. 1789-1797 ◽  
Author(s):  
Thomas Sauvigny ◽  
Katja Brückner ◽  
Lasse Dührsen ◽  
Oliver Heese ◽  
Manfred Westphal ◽  
...  

Cancer ◽  
2009 ◽  
Vol 115 (24) ◽  
pp. 5771-5779 ◽  
Author(s):  
Ji Hoon Phi ◽  
Seung-Ki Kim ◽  
Byung-Kyu Cho ◽  
Seo Young Lee ◽  
Su Yeon Park ◽  
...  

2011 ◽  
Vol 26 (8) ◽  
pp. 739-745 ◽  
Author(s):  
R. M. Busch ◽  
M. F. Dulay ◽  
K. H. Kim ◽  
J. S. Chapin ◽  
L. Jehi ◽  
...  

2021 ◽  
pp. 1-11
Author(s):  
Chifaou Abdallah ◽  
Hélène Brissart ◽  
Sophie Colnat-Coulbois ◽  
Ludovic Pierson ◽  
Olivier Aron ◽  
...  

OBJECTIVEIn drug-resistant temporal lobe epilepsy (TLE) patients, the authors evaluated early and late outcomes for decline in visual object naming after dominant temporal lobe resection (TLR) according to the resection status of the basal temporal language area (BTLA) identified by cortical stimulation during stereoelectroencephalography (SEEG).METHODSTwenty patients who underwent SEEG for drug-resistant TLE met the inclusion criteria. During language mapping, a site was considered positive when stimulation of two contiguous contacts elicited at least one naming impairment during two remote sessions. After TLR ipsilateral to their BTLA, patients were classified as BTLA+ when at least one positive language site was resected and as BTLA− when all positive language sites were preserved. Outcomes in naming and verbal fluency tests were assessed using pre- and postoperative (means of 7 and 25 months after surgery) scores at the group level and reliable change indices (RCIs) for clinically meaningful changes at the individual level.RESULTSBTLA+ patients (n = 7) had significantly worse naming scores than BTLA− patients (n = 13) within 1 year after surgery but not at the long-term evaluation. No difference in verbal fluency tests was observed. When RCIs were used, 5 of 18 patients (28%) had naming decline within 1 year postoperatively (corresponding to 57% of BTLA+ and 9% of BTLA− patients). A significant correlation was found between BTLA resection and naming decline.CONCLUSIONSBTLA resection is associated with a specific and early naming decline. Even if this decline is transient, naming scores in BTLA+ patients tend to remain lower compared to their baseline. SEEG mapping helps to predict postoperative language outcome after dominant TLR.


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