Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers

Molecular Therapy ◽

10.1016/j.ymthe.2017.08.010 ◽

2017 ◽

Vol 25 (12) ◽

pp. 2607-2619 ◽

Author(s):

Elizabeth L. Siegler ◽

Yu Jeong Kim ◽

Xianhui Chen ◽

Natnaree Siriwon ◽

John Mac ◽

...

Keyword(s):

Natural Killer Cells ◽

Cancer Therapy ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Drug Carriers ◽

Killer Cells ◽

Combination Cancer Therapy

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Chimeric antigen receptor-engineered natural killer cells: a promising cancer immunotherapy

Expert Review of Clinical Immunology ◽

10.1080/1744666x.2021.1911648 ◽

2021 ◽

Author(s):

Kajal Chaudhry ◽

Ehsan Dowlati ◽

Catherine M. Bollard

Keyword(s):

Natural Killer Cells ◽

Cancer Immunotherapy ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

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High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia

Frontiers in Immunology ◽

10.3389/fimmu.2019.03123 ◽

2020 ◽

Vol 10 ◽

Author(s):

Stephan Müller ◽

Tobias Bexte ◽

Veronika Gebel ◽

Franziska Kalensee ◽

Eva Stolzenberg ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Natural Killer Cells ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Lymphoblastic Leukemia ◽

Antigen Receptor ◽

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2B4 costimulatory domain enhancing cytotoxic ability of anti-CD5 chimeric antigen receptor engineered natural killer cells against T cell malignancies

Journal of Hematology & Oncology ◽

10.1186/s13045-019-0732-7 ◽

2019 ◽

Vol 12 (1) ◽

Author(s):

Yingxi Xu ◽

Qian Liu ◽

Mengjun Zhong ◽

Zhenzhen Wang ◽

Zhaoqi Chen ◽

...

Keyword(s):

T Cell ◽

Natural Killer Cells ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Killer Cells ◽

T Cell Malignancies

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Therapeutic Effects of ALT-803, an IL-15 Superagonist, in Combination with Anti-CD20 Chimeric Antigen Receptor Modified Expanded Natural Killer Cells Against Burkitt Lymphoma (BL)

Cytotherapy ◽

10.1016/j.jcyt.2016.03.194 ◽

2016 ◽

Vol 18 (6) ◽

pp. S96

Author(s):

Y. Chu ◽

F. Lee ◽

J. Ayello ◽

B. Hang ◽

M. Zhang ◽

...

Keyword(s):

Natural Killer Cells ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Burkitt Lymphoma ◽

Antigen Receptor ◽

Therapeutic Effects ◽

Killer Cells ◽

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Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer

Frontiers in Immunology ◽

10.3389/fimmu.2018.00283 ◽

2018 ◽

Vol 9 ◽

Author(s):

Rohtesh S. Mehta ◽

Katayoun Rezvani

Keyword(s):

Natural Killer Cells ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Killer Cells ◽

Immunotherapy Of Cancer

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Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival

OncoImmunology ◽

10.1080/2162402x.2015.1119354 ◽

2015 ◽

Vol 5 (4) ◽

pp. e1119354 ◽

Author(s):

Sabrina Genßler ◽

Michael C. Burger ◽

Congcong Zhang ◽

Sarah Oelsner ◽

Iris Mildenberger ◽

...

Keyword(s):

Natural Killer Cells ◽

Antitumor Activity ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Antigen Expression ◽

Target Antigen ◽

Killer Cells ◽

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Development of GPC3-Specific Chimeric Antigen Receptor-Engineered Natural Killer Cells for the Treatment of Hepatocellular Carcinoma

Molecular Therapy ◽

10.1016/j.ymthe.2017.12.012 ◽

2018 ◽

Vol 26 (2) ◽

pp. 366-378 ◽

Author(s):

Min Yu ◽

Hong Luo ◽

Mingliang Fan ◽

Xiuqi Wu ◽

Bizhi Shi ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Natural Killer Cells ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

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Therapeutic Targeting of Follicular Helper T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells

SSRN Electronic Journal ◽

10.2139/ssrn.3335775 ◽

2019 ◽

Author(s):

Seth D. Reighard ◽

Stacey A. Cranert ◽

Kelly M. Rangel ◽

Ayad Ali ◽

Arthur T. de la Cruz-Lynch ◽

...

Keyword(s):

T Cells ◽

Natural Killer Cells ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Helper T Cells ◽

Follicular Helper T Cells ◽

Therapeutic Targeting ◽

Killer Cells ◽

Follicular Helper

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Abstract A59: Expression of membrane-bound IL-15/IL-15Rα complex in chimeric antigen receptor-engineered natural killer cells for enhanced efficacy against solid tumors

10.1158/2326-6074.tumimm17-a59 ◽

2018 ◽

Author(s):

Elizabeth L. Siegler ◽

Pin Wang

Keyword(s):

Natural Killer Cells ◽

Natural Killer ◽

Solid Tumors ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Killer Cells ◽

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Development of c‑MET‑specific chimeric antigen receptor‑engineered natural killer cells with cytotoxic effects on human liver cancer HepG2 cells

Molecular Medicine Reports ◽

10.3892/mmr.2019.10529 ◽

2019 ◽

Author(s):

Bing Liu ◽

Zheng‑Zhi Liu ◽

Mei‑Ling Zhou ◽

Jian‑Wei Lin ◽

Xue‑Mei Chen ◽

...

Keyword(s):

Natural Killer Cells ◽

Liver Cancer ◽

Natural Killer ◽

Chimeric Antigen Receptor ◽

Hepg2 Cells ◽

Human Liver ◽

Antigen Receptor ◽

Cytotoxic Effects ◽

Killer Cells ◽

Human Liver Cancer

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